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25 Cards in this Set
- Front
- Back
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Where can you gain water the most?
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in fluid 1200 mL/day
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Where can you loose water in your body the most?
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Urine 1500 mL/day
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What is regulated in our body?
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unlike water, sweating, defecation, evaporation, renal water loss is regulated
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If intake exceeds losses, water balance is positive or negative?
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POSITIVE
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If Intake is less than losses, whater balance is Negative or Positive?
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NEGATIVE
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What is called: removal of access water by the kidney
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water diuresis
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How is water diuresis achieved?
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minimal alteration and solute excretion
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What does the proximal tubule reabsorb the most?
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Large quanit of solutes and water
* follows by mosmosis leaving osmolarity unchanged. |
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Which part of the tubule is HIGHLY permeable to water?
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thin descending tuble of the loop of henle.
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Which reabsorbs solute the most in the tubule?
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Ascending limp of loop, esp thick segment, and early distal tubule actively reabsorbs solute but is impermeable to water.
Osmolarity drops to 100 mOsm/L. |
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Which section of the tuble is water permeability is hormonally controlled and in most extreme diuresis highly limited yielding urine osmolarity of 50 mOsm/L.?
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Late distal tubule, collecting tuble and collecting duct
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What is Anti Diuresis?
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concentrated urine. Under negative water balance, water is conserved by renal reabsorption
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In Anti Diuresis, Which tubule section is permeable to water?
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dital tubule, collecting tubule, and collecting duct.
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Depending on the level od permeability, the urine is concentrated up to what level?
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1200 mOsm/L
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What is the cause of Diabetes Insipidus?
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neurogenic ADH deficiency (plasma osmolarity go down) d/t head trauma, surgery, neoplastic lesion
nephrogenic insensitivity to vasopressin |
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What are the symptoms of Diabetes Insipidus?
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Polyuria (lots of urine production)
Polydipsia (thirsty) |
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What is the treatment of Diabetes Insipidus?
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Vasopressin or Desmopressin-- neurogenic form
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How would you differentiate neurogenic vs. nephrogenic?
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If neurogenic, plasma osmolarity will GO DOWN. If nephrogenic, it will NOT!
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What is Syndrome of Inappropriate ADH Secretion? (SIADH)
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retain water, body fluids become hypoosmotic, urine very concentrated
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What lab results will you see in a Syndrome of Inappropriate ADH Secretion? (SIADH) pt?
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Elevated plasma ADH levels
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What are the causes of Syndrome of Inappropriate ADH Secretion? (SIADH)?
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infections and neoplasms of brain, drugs, pulmonary disease and some carcinomas
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Tubule Reabsorption Characteristics of thin Descending limb
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permeable to water but NOT solute
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Tubule Reabsorption Characteristics of thin Ascending limb
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permeable to solute NOT WATER
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Tubule Reabsorption Characteristics of thick ascending limb
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permeable to solute but not water
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For counter current multiplier, extracellular osmolarity gradient is established by what type of transport system?
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Active and Passive transport of solutes out of teh tubule and the equilbration of filtrate osmolarity.
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