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49 Cards in this Set

  • Front
  • Back
4 major functions of the circulatory system
1. Transportation
2. Temp Regulation
3. Wound Care
4. Immune Function
Divides heart top from bottom, both sides dont contract simultaneously
Fibrous Skeleton
outer layer, tough connective tissue not connected to the heart
Pericardium
Actual heart wall
connective tissue, fat, blood vessels
Epicardium
Muscle layer of heart with slow-twitch fibers, middle
Myocardium
innermost layer of the heart
Endocardium
Cardiac muscle structure and function
branching structure to prevent damage, gap junctions for direct communication between fibers, function: generate pressure
electrically unstable, generates spontaneous AP, initiates heartbeat, pacemaker
SA node
What is the primary modifier of heart rate?
Autonomic innervation of the SA node
slower than normal heart rate at rest
least dangerous
bradycardia
fast heart rate at rest
tachycardia
no coordination, random contraction
most dangerous
fibrillation
Volume at the end of contraction (in the ventricle)
End Systolic Volume
Volume at the end of relaxation before contraction, (max blood in ventricle)
End Diastolic Volume
Blood amount pumped out of the heart (ventricle) in a single beat
(EDV-ESV)
Stroke Volume
Pressure Volume Loop
-min pressure and volume (ESV)
A
Pressure Volume Loop
-max volume (EDV)
-min pressure change
B
Pressure Volume Loop
-exceed aortic pressure
-open semilunar valve
C
Pressure Volume Loop
-semilunar valve closes
D
Ventricular "ejection fraction"
SV/EDV
Amount of blood pumped out of a ventricle in a minute
Cardiac output
Cardiac output
SV x HR

avg: 5.5 so takes one min to travel though body in blood
three factors that determine Stroke Volume
1. End Diastolic Volume ^
2. Total Peripheral ResistanceV
3. Contractility
Sum of resistance outside the heart
resistance to blood flow
Total peripheral resistance
Is peripheral resistance higher in systemic or pulmonary circulation?
Systemic- higher
Close/open capillary beds
in arterioles
precapillary sphincters
Type of capillary
-majority with tight juntions
Continuous
Type of capillary
-300x more leaky, windows
Fenestrated
Type of capillary
-gaps between cells, move large elements
-in bone marrow, liver
Discontinuous
High point pressure of arteries during contraction
Systolic pressure

normal:120
Lowest pressure at the end of relaxation
Diastolic pressure

normal: 80
Pulse Pressure
systolic BP- diastolic BP
Mean Arterial Pressure
1/3 PP + diastolic BP
three main factors that determine Arterial BP
1. Cardiac output
2. Total Blood Volume
3. Total Peripheral Resistance
Sensory receptors that measure pressure changes, communicate with CNS
Baroreceptors
Regulate blood volume, long term control
Hormones
-control BP
-ADH Aldosterone
thincker L ventricle wall, muscle grows inward, decreasing volume
can be caused by hypertension
Pathological Hypertrophy
-clot formation
-cause vasoconstriction
Platelets
the formation of blood cells from stem cells is bone marrow and lymph nodes
Hematopoiesis
formation of RBCs (bone marrow, fast rate)
Erythropoesis
formation of WBCs
Leukopoesis
=cessation of bleeding
1. vasoconstriction
2. formation of platelet plug
3. Fibrin web
Hemostasis
movement of fluid from capillary plasma to ISF
Filtration
movement of fluid from ISF to capillary plasma
Absorption
sum of pressure driving OUT
hydrostatic pressure in capillary
oncotic pressure of ISF
Sum of pressure driving IN
hydrostatic pressure of ISF
oncotic pressure of blood plasma
Net Fluid Movement
OUT (filtration) - IN (absorption)
stronger of the two forces?
filtration/absorption
Filtration
-blood entering veins is more dehydrated
Lymphatic System 3 main functions
1. pick up excess fluid in capillary beds, return to veins
2. trans absorbed fat from small intest--blood
3. immunological defense