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7 Cards in this Set

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Body fluid compartment measurement with dye-dilution
[A1] (mg/ml) x Vol1 (ml) = amount of A (mg) = [A2] x Vol2

A1 = known concentration of substance
Vol1= known volume of substance

A2 = concentration of distributed subtance in body compartment
Vol 2 is volume of body compartment
He dilution
- FRC = V1(C1-C2)/C2
- C1 = initial [He]
- C2 = final [He]
- V1 initial volume of system
- boyle's law to find FRC
- airtight box of known V
- P measured in box and at airway during inspiration effort at closed airway
- V1 = volume in box
- V2 = volume after inspiration
- change in volume = volume of thorax
- P3 and p4 are pressure in airway before and after inspiration P3v3 = p4(V3+ change in V)
- V3 = FRC

FRC = P4 (change in V/ change in P)
Folwer method
- measures deadspace
- 100% O2 in, V and [N] measured on exhalation
- no increase in N initially, but incrases to an S curve gradually before a plateau
- horizontal line from plateau, vertical tangent to it, through S curve
- alveolar gas = plateau
- value at which perpendicular intersects Volume axis is anatomic dead space
Bohr Method
- physiological and anatomical dead space
- yield same as Fowlers
- when high physiologic deadspace bohr --> large value
- Vd/Vt =
- (PaCO2 - PECO2)/ PaCO2
PaCO2 = partial pressure of CO2 in arterial blood
PECO2 = partial pressure of CO2 in expired air
- normal is .2 - .4
Flow rate
V = ΔP/R
P = driving force
R = resistance
V= flowrate (with a dot over it)
Poiseuille's Law
R = 8nl/pi r^4

flowrate and pressure under laminar flow
- R = resistance
- n = viscosity of gas
- l = length of tube