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29 Cards in this Set

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What is the overall organization of epithelial cells?
Form sheets, unlike CT
Can be single layered or multilayered
Can you see intercellular matrix or fibers in LM?
No
In what (EM or LM) can you see the specialized junctions between epithelial cells?
EM
Function of junctions
1. Provide mechanical support
2. Establish functional difference between apical and basal compartments of the sheet and the individual cells.
Polarized epithelial cells means?
There is an apical and basal portion of the cell
Apical portion of cell
The interior of the lumen it lines or the outer surface it covers
Basal portion of the cell
The basement membrane which it rests
Separates the epithelium from other tissues
How are epithelia classified?
The shapes of their cells and the number of cell layers within the epithelial sheet

The shape & position of nucleus
Glands
-Type of secretions: Serous or mucous
-Arrangment of cells: tubular or acinar
-Degree of complexity: simple or branched
-Presence of absence of specialized ducts.
Occluding junctions (zonula occludens and tight junctions)
-small intercellular space
-always the most apical
-fuse at "kisses"
Zonula adherens
-located under occluding jxns
-"belt-like"
Desmosome or macula adherens
-located under zonula adherens
Hemidesmosome
-links epithelium to basal lamina
Junctional complexes
The ensemble of junctions common in epithelial sheets
Microvilli
-geared toward increased surface area & motility
Cilia
Motility, help move materials in airway or lumen
Basolateral folds
-includes: intercellular contact between epithelial cells, intercellular junctions, basal junctions between epithelium and basal lamina
-large surface area
-many mitochondira
Simple squamous
-flat
-1 layer
-found in areas of high rate transport
-Endothelium: lining of blood & lymph vessels
Simple cuboidal
-cube-shaped with round, central nucleus
-secretory or absorptive
Simple columnar
-cells are taller than wide
-round nucleus in basal compartment
-secretory or absorptive
Psuedostratified columnar
-multiple cell types
-different heights
-nuclei with different placement
-may look layered, but still a single layer
-all cells attached to basal lamina, but may not reach apical surface
-In trachea, bronchii, male repro. tract
Simple stratified
-stem cells located in basal layer
Stratified squamous, non-keratinized
-impermeable barrier
-vagine & esophagus
Stratified squamous, keratinized
epidermis
Stratified cuboidal/coumnar
-line ducts
-not very permeable, involved in structural support
Transitional
-multiple layers of round or polygon cells
-cells can be binucleate
Metaplasia
-transformation of epithelium type due to changes in environment
Endocrine
discharge product to underlying CT
Exocrine
discharge product to outside the lumen or to a duct that empties into a lumen