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120 Cards in this Set

  • Front
  • Back
Neuraxis
an imaginary line drawn through the centre of the length of the CNS from the bottom of the spinal cord to the front of the forehead
Anterior
with respect to CNS, located near or toward the head
Posterior
with respect to CNS, located near or toward the tail
Rostral
REMEMBER "ROSTRUM" MEANS ROOSTER'S BEAK IN LATIN***
“toward the beak”; with respect to CNS, in a direction along the neuraxis toward the front of the face
Caudal
“toward the tail”; with respect to CNS, in a direction along neuraxis away from face
Dorsal
“toward the back”, with respect to CNS, in a direction perpendicular to neuraxis toward top of head or back
Ventral
“toward the belly”, with respect to CNS, in a direction perpendicular to neuraxis towards bottom of skull or front surface of body
Lateral
Toward the side
Medial
Toward the middle
Ipsilateral
located on same side of
Contralateral
located on the opposite side of the body
Cross sections:
with respect to CNS, a slice taken at right angles with neuraxis (like a “salami” we cut)
Frontal sections
a slice through the brain parallel to the forehead
Horizontal sections:
a slice through the brain parallel to the ground
Sagittal sections
a slice through the brain parallel to the neuraxis and perpendicular to the ground
Midsagittal plane
the plane through the neuraxis perpendicular to the ground; divides the brain into 2 symmetical halves
Meninges
the three layers of tissue that encase the CNS: dura mater, arachnoid mater, pia mater
Dura mater:
"tough mother" the outermost of the meninges, tough and flexible
Arachnoid membrane
the middle later of meninges, located b/n dura and pia mater, soft and spongy
Pia mater
the layer of meninges that clings to the surface of the brain; thin and delicate
Ventricle
“little belly” – one of the hollow spaces w/in the brain filled with cerebrospinal fluid
Lateral ventricles
one of the 2 ventricles located in the centre of the telencephalon (on the side of head)
Third ventricle
the ventricle located in the centre of the diencephalon (located at midline of brain; divide into symmetrical halves)
Cerebral aqueduct
a narrow tube interconnecting the 3rd ventricle and 4th ventricles of the brain, located in the centre of the mesencephalon
Fourth ventricle
the ventricle located b/n the cerebellum and the dorsal pons, in the center of the metencephalon
Chroid plexus
MAKES CSF
the highly vascular tissue that protrudes into the ventricles and produces CSF
Arachnoid granulations
small projections of the arachnoid membrane through the dura mater into the superior sagittal sinus; CSF flows through them to be reabsorbed into the blood stream
Superior sagittal sinus
a venous sinus located in the midline just dorsal to the corpus callosum, between the two cerebral hemispheres
Obstructive hydrocephalus
a condition in which all or some of the brain’s ventricles are enlarged; caused by an obstruction that impedes the normal flow of CSF (enlargement of ventricles & brain damage)
Neural tube
a hollow tube, closed at the rostral end, that forms from ectodermal tissue early in embryonic dev; serves as origin of CNS
What are the major divisions of the brain?
1. Forebrain
2. Midbrain
3. Hindbrain
What are the subdivisions of the brain?
1. Telencephalon ("end brain")
2. Diencephalon ("interbrain")
3. Mesencephalon
4. Metencephalon ("after brain")
5. myelencephalon ("marrowbrain")
Cerebral cortex
the outermost layer of gray matter of the cerebral hemispheres.
Progenitor cells
"parent cells"
cells of the ventricular zone that divide and give rise to cells of the CNS
Ventricular zone
a layer of cells that line the inside of the neural tube; contains progenitor cells that divde and give rise to cells of the CNS
Subventricular zone
a layer of progenitor cells located just inside the ventricular zone; thicker in mammals with large brains
symmetrical division
division of progenitor cell that gives rise to two identical progenitor cells’ increases the size of ventricular zone and the brain that develops from it
Asymmetrical division
(next phase in progenitor cells...)
division of a progenitor cell that gives rise to another progenitor cell AND a neuron, which migrates away from VZ to its final resting place in the brain
Radial glia
special glia with fibers that grow radially outward from the VZ to the surface of the cortex; provide guidance for neurons migrating outwards dur brain dev
Apoptosis
death of a cell caused by chemical signal that activates a genetic mechanism inside the cell
Neurogenesis
production of new neurons through the division of neural stem cells; CAN occur in the hippocampus and the olfactory bulb and appears to play a role in learning
Forebrain
the most rostral of the three major divisions of the brain; includes the telencephalon and diencephalon
Cerebral hemisphere
one of two major portions of the forebrain, covered by the cerebral cortex
Subcortical region
the region located within the brain, beneath the cortical surface
Sulcus
a groove in the surface of the cerebral hemisphere, smaller than a fissure
Fissure
a major groove in the surface of the cere. Hemisphere, larger than sulcus
Gyrus
A convolution of the cortex of the cereb. Hemisphere, separate by sulci or fissures
Why is grey matter grey and white matter white?
Gray matter: cell bodies give gray look
White matter: myelin gives white look
Primary visual cortex
the region of the posterior occipital lobe whose primary input is the visual system
Primary auditory cortex
the region of the superior temporal lobe whose primary input is the auditory system
Lateral fissure
the fissure that separates the temporal lobe from the overlying frontal and parietal lobes
Primary somatosensory cortex
the region of the anterior parietal lobe whose primary input is from the somatosensory system
Central sulcus
a sulcus that separates frontal lobe from parietal lobe
Primary motor cortex
the region of the posterior frontal lobe that contains neurons that control movements of skeletal muscles
Frontal lobe
the anterior portion of the cerebral cortex, rostral (towards face) to the parietal lobe and dorsal to the temporal lobe
Parietal lobe:
the region of the cerebral cortex caudal to the frontal lobe and dorsal (towards top of head) to the temporal lobe
Temporal lobe
the region of c.c. rostral to occipital lobe and ventral (towards bottom of skull) to the parietal and frontal lobes
Occipital lobe
the region of the cc. caudal (away from face) to parietal and temporal lobes
Sensory association cortex
those regions of the cerebral cortex that receive information from the regions of the primary sensory cortex
Motor association cortex
the region of the frontal lobe rostral (towards face) to primary motor cortex, also known as PREMOTOR CORTEX
Prefrontal cortex
less involved with movement and more with formulating plans; region of brain rostral to motor association cortex
Corpus callosum
a large bundle of axons that interconnects corresponding regions of the association cortex on each side of the brain
Neocortex
(frontal, parietal, occipital, temporal) “new” phylogenetically newest cortex, including the primary sensory corted, primary motor cortex and association cortex
Limbic cortex
“limbus means border” – located around eges phylogenetically oldest cortex, located on medial edge of cerebral hemispheres; part of limbic system
Cingulate gyrus
a strip of limbic cortex lying along the lateral walls of the groove separating the cerebral hemispheres – just above the corpus callosum
Limbic system
a group of brain regions including the anterior thalamic nuclei, amygdala, hippocampus, limbic cortex, and part of the hypothalamus, as well as their interconnecting fiber bundles
Amygdala “almond”:
a structure in the interior of the rostral temporal lobe, containing a set of nuclei; part of the limbic system EMOTION
Hippocampus “sea horse”:
a forebrain structure of the temporal lobe, constituting an important part of the limbic system, includes the hippocampus proper (Ammon’s horn), dentate gyrus and subiculum MEMORY
Fornix “arch”:
a fiber bundle that connects the hippocampus with the other parts of the brain, including the mammillary bodies of the hypothalamus; part of the limbic system
Mammillary “breast shaped” bodies
protrusions of the bottom of the brain at the posterior end of the hypothalamus, containg some hypothalamic nuclei; part of the limbic system
Basal ganglia
a group of subcortical nuclei in the telencephalon, the caudate nucleus, the globus pallidus, and the putamen, important parts of the motor system
Nucleus
an identifiable group of neural cell bodies in the central nervous system
Diencephalon
a region of the forebrain surrounding the third ventricle, includes the thalamus and hypothalamus
Thalamus
“inner chamber”; the largest portion of the diencephalon, located above the hypothalamus; contain nuclei that project info to the specific regions of the cerebral cortex and receive info from it
Projection fiber
axon of a neuron in one region of the brain whose terminals form synapses with neurons in another region
Thalamus
receive info from sensory and then send it to specific sensory projection areas of cerebral cortex
Lateral geniculate nucleus
a group of cell bodies within the lateral geniculate body of the thalamus that receives fibers from the retina and projects fibers to the primary visual cortex
Medial geniculate nucleus
a group of cell bodies within the medial geniculate body of the thalamus; receives fibers from the auditory system and projects fibers to the primary auditory cortex
Ventrolateral nucleus
a nucleus of the thalamus that receives inputs from the cerebellum and sends axons to the primary motor cortex
Hypothalamus
- the group of nuclei of the diencephalon situated beneath the thalamus; involved in the regulation of the autonomic nervous system, anterior/pituitary glands and species typical behaviour
- organizes FOUR “F” BEHAVIOURS: fighting, feeding, fleeing and mating
Optic chiasm
an X shaped connection between optic nerves, located below the base of the brain, just anterior to the pituitary gland
Anterior pituitary gland
the anterior part of the pituitary gland; an endocrine gland whose secretions are controlled by the hypothalamic hormones
HORMONES!!!
Neurosecretory cells:
a posterior part of the pituitary gland; an endocrine gland that contains hormone-secreting terminal buttons of axons whose cell bodies lie within the hypothalamus
- control oxytocin = contractions/milk
- vasopressin = urine output kidneys
Midbrain
the mesencephalon; the central of the three major divisions of the brain
Tectum
“roof” the dorsal part of the midbrain; includes superior and inferior colliculi
Superior colliculi
protrusions on the top of the midbrain; part of VISUAL system
Inferior colliculi
protrusions on top of the midbrain; part of the AUDITORY system
Brain stem
the “Stem” of the brain, from the medulla to the midbrain, excluding the cerebellum
Tegentum
“covering” the ventral part of the midbrain; includes the periaqueductal gray matter, reticular formation, red nucleus and the substantianigra
Reticular formation
“little net” a large network of neural tissue located in the central region of the brain stem, from medulla to diencephalon
Periqueductal gray matter
the region of the midbrain surrounding the cerebral aqueduct; contains neural circuitis involved in species typical behaviour
- control sequences of movements e.g. fighting and mating
Red nucleus
a large nucleus of the midbrain that receives inputs from the cerebellum and motor cortex and sens axons to motor neurons of the spinal cords MOTOR SYSTEM
Substantia nigra: “Black substance”
a darkly stained region of the tementum that contains neurons that communicate with the caudate nucleus and the putamen of the basal ganglia
- degeneration of these neurons = Parkinson’s
Cerebellum
a major part of the brain located dorsal to the pons, containing two cerebellar hemispheres, covered with cerebellar cortex, an important component of MOTOR system
Cerebellar cortex
cortex covers surface of cerebellum
Deep cerebellar nuclei
nuclei located within the cerebellar hemispheres; receive projections from the cerebellar cortex and send projections out of the cerebellum to other parts of the brain
Cerebellar peduncle
one of three bundles of axons that attach each hemisphere to the dorsal pons
- damage to cerebellum= motor problems
Medulla oblongata:
the most caudal portion of the brain; located in the myencephalon; immediately roxtral to the spinal cord
Spinal cord
the cord of the nervous tissue that extends caudally from the medulla
- distribute motor fibers and collect somatosensory info and bring to brain
- consists of white and gray matter (white matter outside, gray matter inside, unlike the brain)
Spinal root
a bundle of axons surrounded by connective tissue that occurs in pair, which fuse and form a spinal nerve
Cauda equina
a bundle of spinal roots located caudal to the end of the spinal cord
Caudal block
the anesthesia and paralysis of the lower part of the body produced by injection of a local anesthetic into the cerebrospinal fluid surrounding the cauda equine
Dorsal root
the spinal root that contains incoming (afferent) sensory fibers
Ventral root
the spinal root that contain outgoing (efferent) motor fibers
Spinal nerves
a peripheral nerve attached ot spinal cord
- leave veterbral column and branch out as they go
Afferent axons
an axon directed toward the CNS, conveying sensory info
- retina of eye actually part of brain and relays info (exception that others are all OUTSIDE OF brain)
Dorsal root ganglia
a nodule of a dorsal root that contains cell bodies of afferent spinal nerve nodules
Efferent axon
an axon directed AWAY from the CNS, conveying motor commands to muscles and glands
Cranial nerves
a peripheral nerve attached directly to the brain
vagus nerve:
largest of cranial nerves, conveying efferent fibers of the parasympathetic division of the autonomic nervous system to organ of the thoracic and abdominal cavities
- "vagus” from vagabond because wanders through abdominal cavities
olfactory bulbs
(protrusion at end of olfactory nerve; receives input from olfactory receptors)
Somatic nervous system
the part of PNS controls movement of skeletal muscles and transmits somatosensory info to cNS
Autonomic nervous system:
portion of PNS that control body’s vegetative functions
- splits into sympathetic and parasympathetic
- relies on both for different functions
- e.g. symp. Increases heart rate; parasymp. Slows it
Sympathetic division
portion of ANS that controls functions accompany arousal and expenditure of energy
Sympathetic ganglia
nodules that contain synapses between preganglionic and postganglionic neurons of the sympathetic nervous system
Sympathetic ganglion chain
one of a pair of groups of sympathetic ganglia that lie ventrolateral to the veterebral column
Preganglionic neurons
the efferent neuron of the ANS whose cell body in cranial nerve nucleus or in the intermediate horn of the spinal gray matter and whose terminal buttons synapse upon postganglionic neurons in autonomic ganglia
Postganglionic neurons:
neurons of ANS form synapses directly with target organ
Adrenal medulla
inner portion of adrenal gland, located atop kidneys, controlled by symp, secrete epinephrine and norepinephrine
Parasympathetic division
portion of ANS that controls rest state of organism
- Increase body’s supply of stored energy