Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
120 Cards in this Set
- Front
- Back
Neuraxis
|
an imaginary line drawn through the centre of the length of the CNS from the bottom of the spinal cord to the front of the forehead
|
|
Anterior
|
with respect to CNS, located near or toward the head
|
|
Posterior
|
with respect to CNS, located near or toward the tail
|
|
Rostral
|
REMEMBER "ROSTRUM" MEANS ROOSTER'S BEAK IN LATIN***
“toward the beak”; with respect to CNS, in a direction along the neuraxis toward the front of the face |
|
Caudal
|
“toward the tail”; with respect to CNS, in a direction along neuraxis away from face
|
|
Dorsal
|
“toward the back”, with respect to CNS, in a direction perpendicular to neuraxis toward top of head or back
|
|
Ventral
|
“toward the belly”, with respect to CNS, in a direction perpendicular to neuraxis towards bottom of skull or front surface of body
|
|
Lateral
|
Toward the side
|
|
Medial
|
Toward the middle
|
|
Ipsilateral
|
located on same side of
|
|
Contralateral
|
located on the opposite side of the body
|
|
Cross sections:
|
with respect to CNS, a slice taken at right angles with neuraxis (like a “salami” we cut)
|
|
Frontal sections
|
a slice through the brain parallel to the forehead
|
|
Horizontal sections:
|
a slice through the brain parallel to the ground
|
|
Sagittal sections
|
a slice through the brain parallel to the neuraxis and perpendicular to the ground
|
|
Midsagittal plane
|
the plane through the neuraxis perpendicular to the ground; divides the brain into 2 symmetical halves
|
|
Meninges
|
the three layers of tissue that encase the CNS: dura mater, arachnoid mater, pia mater
|
|
Dura mater:
|
"tough mother" the outermost of the meninges, tough and flexible
|
|
Arachnoid membrane
|
the middle later of meninges, located b/n dura and pia mater, soft and spongy
|
|
Pia mater
|
the layer of meninges that clings to the surface of the brain; thin and delicate
|
|
Ventricle
|
“little belly” – one of the hollow spaces w/in the brain filled with cerebrospinal fluid
|
|
Lateral ventricles
|
one of the 2 ventricles located in the centre of the telencephalon (on the side of head)
|
|
Third ventricle
|
the ventricle located in the centre of the diencephalon (located at midline of brain; divide into symmetrical halves)
|
|
Cerebral aqueduct
|
a narrow tube interconnecting the 3rd ventricle and 4th ventricles of the brain, located in the centre of the mesencephalon
|
|
Fourth ventricle
|
the ventricle located b/n the cerebellum and the dorsal pons, in the center of the metencephalon
|
|
Chroid plexus
|
MAKES CSF
the highly vascular tissue that protrudes into the ventricles and produces CSF |
|
Arachnoid granulations
|
small projections of the arachnoid membrane through the dura mater into the superior sagittal sinus; CSF flows through them to be reabsorbed into the blood stream
|
|
Superior sagittal sinus
|
a venous sinus located in the midline just dorsal to the corpus callosum, between the two cerebral hemispheres
|
|
Obstructive hydrocephalus
|
a condition in which all or some of the brain’s ventricles are enlarged; caused by an obstruction that impedes the normal flow of CSF (enlargement of ventricles & brain damage)
|
|
Neural tube
|
a hollow tube, closed at the rostral end, that forms from ectodermal tissue early in embryonic dev; serves as origin of CNS
|
|
What are the major divisions of the brain?
|
1. Forebrain
2. Midbrain 3. Hindbrain |
|
What are the subdivisions of the brain?
|
1. Telencephalon ("end brain")
2. Diencephalon ("interbrain") 3. Mesencephalon 4. Metencephalon ("after brain") 5. myelencephalon ("marrowbrain") |
|
Cerebral cortex
|
the outermost layer of gray matter of the cerebral hemispheres.
|
|
Progenitor cells
|
"parent cells"
cells of the ventricular zone that divide and give rise to cells of the CNS |
|
Ventricular zone
|
a layer of cells that line the inside of the neural tube; contains progenitor cells that divde and give rise to cells of the CNS
|
|
Subventricular zone
|
a layer of progenitor cells located just inside the ventricular zone; thicker in mammals with large brains
|
|
symmetrical division
|
division of progenitor cell that gives rise to two identical progenitor cells’ increases the size of ventricular zone and the brain that develops from it
|
|
Asymmetrical division
|
(next phase in progenitor cells...)
division of a progenitor cell that gives rise to another progenitor cell AND a neuron, which migrates away from VZ to its final resting place in the brain |
|
Radial glia
|
special glia with fibers that grow radially outward from the VZ to the surface of the cortex; provide guidance for neurons migrating outwards dur brain dev
|
|
Apoptosis
|
death of a cell caused by chemical signal that activates a genetic mechanism inside the cell
|
|
Neurogenesis
|
production of new neurons through the division of neural stem cells; CAN occur in the hippocampus and the olfactory bulb and appears to play a role in learning
|
|
Forebrain
|
the most rostral of the three major divisions of the brain; includes the telencephalon and diencephalon
|
|
Cerebral hemisphere
|
one of two major portions of the forebrain, covered by the cerebral cortex
|
|
Subcortical region
|
the region located within the brain, beneath the cortical surface
|
|
Sulcus
|
a groove in the surface of the cerebral hemisphere, smaller than a fissure
|
|
Fissure
|
a major groove in the surface of the cere. Hemisphere, larger than sulcus
|
|
Gyrus
|
A convolution of the cortex of the cereb. Hemisphere, separate by sulci or fissures
|
|
Why is grey matter grey and white matter white?
|
Gray matter: cell bodies give gray look
White matter: myelin gives white look |
|
Primary visual cortex
|
the region of the posterior occipital lobe whose primary input is the visual system
|
|
Primary auditory cortex
|
the region of the superior temporal lobe whose primary input is the auditory system
|
|
Lateral fissure
|
the fissure that separates the temporal lobe from the overlying frontal and parietal lobes
|
|
Primary somatosensory cortex
|
the region of the anterior parietal lobe whose primary input is from the somatosensory system
|
|
Central sulcus
|
a sulcus that separates frontal lobe from parietal lobe
|
|
Primary motor cortex
|
the region of the posterior frontal lobe that contains neurons that control movements of skeletal muscles
|
|
Frontal lobe
|
the anterior portion of the cerebral cortex, rostral (towards face) to the parietal lobe and dorsal to the temporal lobe
|
|
Parietal lobe:
|
the region of the cerebral cortex caudal to the frontal lobe and dorsal (towards top of head) to the temporal lobe
|
|
Temporal lobe
|
the region of c.c. rostral to occipital lobe and ventral (towards bottom of skull) to the parietal and frontal lobes
|
|
Occipital lobe
|
the region of the cc. caudal (away from face) to parietal and temporal lobes
|
|
Sensory association cortex
|
those regions of the cerebral cortex that receive information from the regions of the primary sensory cortex
|
|
Motor association cortex
|
the region of the frontal lobe rostral (towards face) to primary motor cortex, also known as PREMOTOR CORTEX
|
|
Prefrontal cortex
|
less involved with movement and more with formulating plans; region of brain rostral to motor association cortex
|
|
Corpus callosum
|
a large bundle of axons that interconnects corresponding regions of the association cortex on each side of the brain
|
|
Neocortex
|
(frontal, parietal, occipital, temporal) “new” phylogenetically newest cortex, including the primary sensory corted, primary motor cortex and association cortex
|
|
Limbic cortex
|
“limbus means border” – located around eges phylogenetically oldest cortex, located on medial edge of cerebral hemispheres; part of limbic system
|
|
Cingulate gyrus
|
a strip of limbic cortex lying along the lateral walls of the groove separating the cerebral hemispheres – just above the corpus callosum
|
|
Limbic system
|
a group of brain regions including the anterior thalamic nuclei, amygdala, hippocampus, limbic cortex, and part of the hypothalamus, as well as their interconnecting fiber bundles
|
|
Amygdala “almond”:
|
a structure in the interior of the rostral temporal lobe, containing a set of nuclei; part of the limbic system EMOTION
|
|
Hippocampus “sea horse”:
|
a forebrain structure of the temporal lobe, constituting an important part of the limbic system, includes the hippocampus proper (Ammon’s horn), dentate gyrus and subiculum MEMORY
|
|
Fornix “arch”:
|
a fiber bundle that connects the hippocampus with the other parts of the brain, including the mammillary bodies of the hypothalamus; part of the limbic system
|
|
Mammillary “breast shaped” bodies
|
protrusions of the bottom of the brain at the posterior end of the hypothalamus, containg some hypothalamic nuclei; part of the limbic system
|
|
Basal ganglia
|
a group of subcortical nuclei in the telencephalon, the caudate nucleus, the globus pallidus, and the putamen, important parts of the motor system
|
|
Nucleus
|
an identifiable group of neural cell bodies in the central nervous system
|
|
Diencephalon
|
a region of the forebrain surrounding the third ventricle, includes the thalamus and hypothalamus
|
|
Thalamus
|
“inner chamber”; the largest portion of the diencephalon, located above the hypothalamus; contain nuclei that project info to the specific regions of the cerebral cortex and receive info from it
|
|
Projection fiber
|
axon of a neuron in one region of the brain whose terminals form synapses with neurons in another region
|
|
Thalamus
|
receive info from sensory and then send it to specific sensory projection areas of cerebral cortex
|
|
Lateral geniculate nucleus
|
a group of cell bodies within the lateral geniculate body of the thalamus that receives fibers from the retina and projects fibers to the primary visual cortex
|
|
Medial geniculate nucleus
|
a group of cell bodies within the medial geniculate body of the thalamus; receives fibers from the auditory system and projects fibers to the primary auditory cortex
|
|
Ventrolateral nucleus
|
a nucleus of the thalamus that receives inputs from the cerebellum and sends axons to the primary motor cortex
|
|
Hypothalamus
|
- the group of nuclei of the diencephalon situated beneath the thalamus; involved in the regulation of the autonomic nervous system, anterior/pituitary glands and species typical behaviour
- organizes FOUR “F” BEHAVIOURS: fighting, feeding, fleeing and mating |
|
Optic chiasm
|
an X shaped connection between optic nerves, located below the base of the brain, just anterior to the pituitary gland
|
|
Anterior pituitary gland
|
the anterior part of the pituitary gland; an endocrine gland whose secretions are controlled by the hypothalamic hormones
HORMONES!!! |
|
Neurosecretory cells:
|
a posterior part of the pituitary gland; an endocrine gland that contains hormone-secreting terminal buttons of axons whose cell bodies lie within the hypothalamus
- control oxytocin = contractions/milk - vasopressin = urine output kidneys |
|
Midbrain
|
the mesencephalon; the central of the three major divisions of the brain
|
|
Tectum
|
“roof” the dorsal part of the midbrain; includes superior and inferior colliculi
|
|
Superior colliculi
|
protrusions on the top of the midbrain; part of VISUAL system
|
|
Inferior colliculi
|
protrusions on top of the midbrain; part of the AUDITORY system
|
|
Brain stem
|
the “Stem” of the brain, from the medulla to the midbrain, excluding the cerebellum
|
|
Tegentum
|
“covering” the ventral part of the midbrain; includes the periaqueductal gray matter, reticular formation, red nucleus and the substantianigra
|
|
Reticular formation
|
“little net” a large network of neural tissue located in the central region of the brain stem, from medulla to diencephalon
|
|
Periqueductal gray matter
|
the region of the midbrain surrounding the cerebral aqueduct; contains neural circuitis involved in species typical behaviour
- control sequences of movements e.g. fighting and mating |
|
Red nucleus
|
a large nucleus of the midbrain that receives inputs from the cerebellum and motor cortex and sens axons to motor neurons of the spinal cords MOTOR SYSTEM
|
|
Substantia nigra: “Black substance”
|
a darkly stained region of the tementum that contains neurons that communicate with the caudate nucleus and the putamen of the basal ganglia
- degeneration of these neurons = Parkinson’s |
|
Cerebellum
|
a major part of the brain located dorsal to the pons, containing two cerebellar hemispheres, covered with cerebellar cortex, an important component of MOTOR system
|
|
Cerebellar cortex
|
cortex covers surface of cerebellum
|
|
Deep cerebellar nuclei
|
nuclei located within the cerebellar hemispheres; receive projections from the cerebellar cortex and send projections out of the cerebellum to other parts of the brain
|
|
Cerebellar peduncle
|
one of three bundles of axons that attach each hemisphere to the dorsal pons
- damage to cerebellum= motor problems |
|
Medulla oblongata:
|
the most caudal portion of the brain; located in the myencephalon; immediately roxtral to the spinal cord
|
|
Spinal cord
|
the cord of the nervous tissue that extends caudally from the medulla
- distribute motor fibers and collect somatosensory info and bring to brain - consists of white and gray matter (white matter outside, gray matter inside, unlike the brain) |
|
Spinal root
|
a bundle of axons surrounded by connective tissue that occurs in pair, which fuse and form a spinal nerve
|
|
Cauda equina
|
a bundle of spinal roots located caudal to the end of the spinal cord
|
|
Caudal block
|
the anesthesia and paralysis of the lower part of the body produced by injection of a local anesthetic into the cerebrospinal fluid surrounding the cauda equine
|
|
Dorsal root
|
the spinal root that contains incoming (afferent) sensory fibers
|
|
Ventral root
|
the spinal root that contain outgoing (efferent) motor fibers
|
|
Spinal nerves
|
a peripheral nerve attached ot spinal cord
- leave veterbral column and branch out as they go |
|
Afferent axons
|
an axon directed toward the CNS, conveying sensory info
- retina of eye actually part of brain and relays info (exception that others are all OUTSIDE OF brain) |
|
Dorsal root ganglia
|
a nodule of a dorsal root that contains cell bodies of afferent spinal nerve nodules
|
|
Efferent axon
|
an axon directed AWAY from the CNS, conveying motor commands to muscles and glands
|
|
Cranial nerves
|
a peripheral nerve attached directly to the brain
|
|
vagus nerve:
|
largest of cranial nerves, conveying efferent fibers of the parasympathetic division of the autonomic nervous system to organ of the thoracic and abdominal cavities
- "vagus” from vagabond because wanders through abdominal cavities |
|
olfactory bulbs
|
(protrusion at end of olfactory nerve; receives input from olfactory receptors)
|
|
Somatic nervous system
|
the part of PNS controls movement of skeletal muscles and transmits somatosensory info to cNS
|
|
Autonomic nervous system:
|
portion of PNS that control body’s vegetative functions
- splits into sympathetic and parasympathetic - relies on both for different functions - e.g. symp. Increases heart rate; parasymp. Slows it |
|
Sympathetic division
|
portion of ANS that controls functions accompany arousal and expenditure of energy
|
|
Sympathetic ganglia
|
nodules that contain synapses between preganglionic and postganglionic neurons of the sympathetic nervous system
|
|
Sympathetic ganglion chain
|
one of a pair of groups of sympathetic ganglia that lie ventrolateral to the veterebral column
|
|
Preganglionic neurons
|
the efferent neuron of the ANS whose cell body in cranial nerve nucleus or in the intermediate horn of the spinal gray matter and whose terminal buttons synapse upon postganglionic neurons in autonomic ganglia
|
|
Postganglionic neurons:
|
neurons of ANS form synapses directly with target organ
|
|
Adrenal medulla
|
inner portion of adrenal gland, located atop kidneys, controlled by symp, secrete epinephrine and norepinephrine
|
|
Parasympathetic division
|
portion of ANS that controls rest state of organism
- Increase body’s supply of stored energy |