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13 Cards in this Set
- Front
- Back
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Hexamethonium
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Ganglionic Blocking Drug
Block impulse transmission from the autonomic preganglionic neurons to the postganglionic neurons |
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Drugs that cause autonomic effects by stimulating postganglionic neurons.
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Nicotinic drugs
Nicotine excites both S & PS postganglionic neurons at the same time |
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Atropine, and homatropine
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Antimuscarinic Drugs
Drugs that block cholinergic activity at effector organs by blocking the action of ACh on muscarinic receptors |
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Pilocarpine and Methacholine
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Direct parasympathomimetics act directly on muscarinic receptors
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Neostigmine, and Pyridostigmine
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Indirect parasympathomimetics act by potentiating the effects of naturally secreted ACh at the PS endings
They act by inhibiting acetylcholinesterase |
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reserpine
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Sympatholytics (Adrenergic activity are blocked)
Synthesis and storage of NE in S nerve endings are prevented. |
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guanethidine
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Sympatholytics (Adrenergic activity are blocked)
Release of NE from S nerve endings can be blocked |
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propranolol
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Sympatholytics (Adrenergic activity are blocked)
Sympathetic beta receptors can be blocked |
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phenoxybenzamine
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Sympatholytics (Adrenergic activity are blocked)
Sympathetic alpha receptors can be blocked. |
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Epinephrine and norepinephrine
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direct sympathomimetic drugs
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Ephedrine, tyramine, amphetamine
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indirect sympathomimetic
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physostigmine
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Cholinesterase inhibitors - inhibit acetylcholinesterase
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Action of Curariform drugs
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compete with acetylcholine for binding sites, but have no intrinsic activity
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