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20 Cards in this Set
- Front
- Back
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What drives glomerular filtration?
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starling forces
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Is filtration in glomerular capillaries much (higher OR lower) than systemic?
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Higher
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What does the Starling equation illustrates?
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the role of hydrostatic and oncotic forces (the so-called Starling forces) in the movement of fluid across capillary membranes.
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What is the solution of the starling equation?
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net filtration OR net fluid movement
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If positive net filtration, fluid will tend to (leave OR enter) the capillary (filtration OR absorption).
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leave; filtration
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If negative net filtration, fluid will tend to (enter or leave) the capillary (filtration OR absorption).
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enter; absorption
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What's GFR?
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Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney
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Renal blood flow
determines Starling Forces and therefore (directly OR indirectly) determines GFR |
indirectly
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Between what range of pressure are the GFR and RBF (renal blood flow) autoregulated?
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90 – 180 mmHg systemic pressure
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The renal artery branches to form what arterioles which supply the glomerulus?
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afferent and then efferent arterioles
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T OR F: Changes in renal artery pressure have a larger
affect on efferent arteriolar resistance. |
False. (afferent)
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Autoregulation via the myogenic mechanism
depends on what channels in smooth muscle? |
Stretch-Activated Calcium channels
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What's the final outcome of the myogenic mechanism of autoregulation?
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Reduces RBF (renal blood flow) and GFR (glomerular flow rate)
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What does the tubuloglomerular feedback (TGF) control?
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regulates glomerular filtration rate (GFR)
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Changes in GFR are detected by?
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renal tubule
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Starling equation for net firltration: (PGC –
PBS) – σ(πGC - πBS) What is PGC? |
hydrostatic (blood) pressure in capillaries
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Starling equation for net firltration: (PGC –
PBS) – σ(πGC - πBS) What is PBS? |
pressure in Bowman's space
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Starling equation for net firltration: (PGC –
PBS) – σ(πGC - πBS) What is π? |
osmotic pressure due to protein in either GC or BS
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Starling equation for net firltration: (PGC –
PBS) – σ(πGC - πBS) What is σ? |
reflection coefficient, but it almost always = 1 b/c protein don't leave the glomerulus
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Starling equation for net firltration: (PGC –
PBS) – σ(πGC - πBS) What is the value of πBS usually? |
0
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