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75 Cards in this Set

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The gradient recalled Echo GRE initially uses _____ to excite the protons

Flip angle less than 90°

The GRE sequence uses a gradient ___ pulse to rephase the protons

Instead of a 180°RF

GRE uses any flip angle (variable) or partial flip

Smaller angle=smaller signal


Can: dephrase and rephrase proton spins

Timing is everything!



if gradient is turned on when protons are in-phase



Gradient on= ____

GRE dephasing

If a gradient is applied to incoherent protons, they will become in-phase



Gradient on= _______

GRE rephrasing

A spolier pulse may be applied to destroy residual transverse magnetization prior to the next pulse



Can be RF or gradient spoiler pulse



What is this called?

Incoherent or "spoiled" gradient echo

A gradient can continually rephrase the protons, keeping them in a "steady state"

Incoherent or "steady state"

What is the difference between incoherent and coherent gradient echo?

Incoherent is "spoiled" and coherent is "steady state"



Incoherent or spoiled gradient echo can be RF or gradient spoiler pulse. A spoiler pulse may be applied to destroy residual transverse magnetization prior to the next pulse.



Coherent or steady state gradient echo is a gradient that can continually rephrase the protons, keeping them in a steady state

Gradients that rephrase are called _____

Spoilers. Spoiler squashes the signal

What is the difference of SE vs. Gradient echo

Spin echo


-initial 90° pulse


-180° pulse used to refocus Mxy and create echo (transverse magnetization)


-produces pure T2 contrast



Gradient echo


-uses a gradient reversal to refocus Mxy (transverse magnetization)


-ONLY can produce T2* contrast, not T2. T1 and PD


-Spoilers RF pulse or gradient (spoiled GRE)

What is this called?


-Initial 90°pulse -180° pulse used to refocus Mxy and create echo (transverse magnetization)-produces pure T2 contrast

Spin echo

What is this called?


-initial low flip angle <90°


-uses a gradient reversal to refocus Mxy


-ONLY can produce T2* contrast, not T2. T1 and PD.


-Spoiler RF pulse or gradient (spoiled GRE)


-shorter TR, shorter TE

Gradient echo

Long TR


Short TE

Spin echo

No 180° pulse!


Faster sequence

Gradient echo

A gradient echo has + shorter TEs and no ____?

180° RF pulse

Gradient echo has shorter TRs and smaller ___?

Flip angles

Gradient echos are shorter overall ____?

Scan time

Gradient echos don't compensate for ___?

Inhomogeneities

What is the difference CSE and GRE?

A CSE (conventional spin echo) parameter

A gradient recall echo parameter

Dephasing is caused by 4 mechanism

1. Spin-spin interactions


2.magnetic field inhomogeneities


3. Magnetic susceptibility


4. Chemical shift

These four mechanisms are caused by ____?


1. Spin-spin interactions 2.magnetic field inhomogeneities 3. Magnetic susceptibility 4. Chemical shift

Dephasing

What are the spin-spin interactions?

What are the magnetic field inhomogeneities?

Magnetic susceptibility

Chemical shift

When a gradient is applied, phase accumulated. This is the principle of _____?

The Phase Encoding Gradient

Balancing gradients foe phase.


-If an equal and opposite gradient is applied, protons rephrase which equals

NO NET PHASE SHIFT

Balancing gradients for phase.


-this is an important part of gradient echo sequences

We must balance the slice select gradient and the frequency encoding gradient for phase so that the ONLY phase difference is from phase encoding!!

How are gradients balanced for phase?

-When a gradient is applied, phase accumulates (principle of phase encoding gradient)


-if an equal and opposite gradient is applied, protons rephrase=no net phase shift


-balance the slice select gradient and the frequency encoding gradient for phase so that the ONLY phase difference is from phase encoding

How are gradients dephased?

-in a GRE sequence, the gradient is applied in one orientation to help the protons dephase faster so that they can be rephased faster

-in a GRE sequence, the gradient is applied in one orientation to help the protons dephase faster so that they can be rephased faster. Why does this work?

Different field strength = different precessional frequency



-the slower protons get behind

How do gradients rephase?

When the gradient orientation is reversed, the slower protons now speed up and the faster ones slow down



-they eventually catch up and all are in phase again

Important points on how gradients rephase

A gradient cannot selectively rephase- ALL types of T2 and T2* dephasing are rephased!

Another important point to how gradients rephase

A GEE sequence can ONLY have T2* weighting!!! And no T2 is produced

Remember...

The 180°RF pulse in a r


Spin echo in a spin Echo sequence rephases everything except the true T2 dephasing

What are the advantages of GEE sequences?

1. Much faster sequences. Less RF energy deposited than spin Echo due to no 180° RF pulse


2. Lower SAR due to no 180° RF pulse.


3. Can be used for breath-hold sequences due to fast times.


4. Sensitive to flow, so can be used to create angio-type images.


Balancing gradients for phase

What are GRE disadvantages?

Fast Gradient Echo is also known as

Prepared rapid gradient echo sequence

Fast Gradient Echo is fast or slow for breath hold exams?

Very fast foe breath hold exams

Fast Gradient Echo sequence uses ___?

T1 or T2 contrast

Fast Gradient Echo uses 90° and/or 180° pulse combinations to ___?

To prepare the contrast before the pulse sequence begins


(Similar to invasion recovery)

What does it mean when ALL echos are collected?

It means that contrast is changing as echoes are taken

Fast Gradient Echo sequences uses echo reordering in ___space to obtain desired contrast

K-SPACE

Single shot EPI uses single excitation pulse to ____?

To acquire an entire image

Single shot EPI


-readout gradient is switched in ___ fashion?

Bipolar

Single shot EPI


Within the FID it generate an entire echo train of ____ and ____ gradient echoes

Ascending and descending

Single shot EPI


The number of gradient echoes is the ___?

EPI factor

Single shot EPI must be fast due to T2* ____?

Decay (100ms)

Single shot EPI


Readout is limited to between ___ and ___ echoes

64 and 128 echoes

Single shot EPI


The effective echo time TEeff coincides with the ___ signal

Maximum

Single shot EPI


Think about it--128 echoes at 100 ms=128000 ms or just ___?

12.8 seconds

What is this called. Multiple phase encoding during multiple gradient recalled echoes

Echoplanar imaging

What are the pros of echoplanar imaging

1. EPI is a phase encoding scheme and can be combined with many spin preparation methods


2. Very fast with new technology (Single image in 50ms)

What are the cons of echoplanar imaging?

1. Expensive technology


2. Requires fancy reconstruction schemes to correct artifacts


3.intrincially T2* weighted due to the use of gradients to rephase


4. Rapidly switching gradients introduce another safety concern- direct neural stimulation (TVMF, peripheral nerve stimulation, magnetophosephenes

What is saturation?

Anytime the NMV is pushes beyond 90° the tissue is said to be partially saturated


-partial saturation leads to decreased signal

What is Saturation if the NMV Flip all the way to 180°

It is fully saturated


-full saturation leads to zero signal


-this can occur after repeated excitation of any tissue=signal fall off over time

Why is Saturation useful?

Because of the spatial (A portion of the anatomy you don't want to see) and chemical shift (specific tissue)

What are the two main types of saturation pulses?

1. Spatial saturation= selectively excites protons due to their location


2. Chemical saturation= selectively excites protons due to their unique frequencies

What is spatial saturation?

selectively excites protons due to their location

What is chemical saturation?

selectively excites protons due to their unique frequencies

What is an advantage of spatial saturation pulses?

Nulls signal from unwanted or moving anatonomy

What are the disadvantages of spatial saturation pulses?

-additional 90°RF pulses increase time


-increased use of RF energy increases SAR

Unwanted anatomy Spatial saturation pulses. Let's say you want to decrease the signal coming from the throat during as sagital c-spine. Place a ___?

Saturation pulse, Sat band on the anterior neck



-this applies a 90° pulse selectively to that region by using the gradients (just like in slice selection)


-the next 90° pulse is the normal excitation pulse for the rest of the tissue, but for the pre-excited tissue it is now thrown into 180° saturation

What are the 4 chemical saturation pulses for fat suppression?



Fat suppression short TI inversion recovery

What are the two methods for fat suppression?

1. Fat saturation


2. STIR

What are the 3 main points for fat saturation? (Fat suppression method 1)

Frequency difference between fat and water

1T=147 HZ


1.5T =220 HZ


3T=440 HZ

Fat saturation image

What are the advantages of fat saturation?

1. Increased appearance of fluid on T2 weighted image (widens dynamic range)


2. Addresses TSE fat-fluid isointensity problem


3. Post gadolinium t1-weighted fat SAT (negating fat signal shows contrast enhancement better)


4. Reduced respiratory motion artifact


Fat saturation disadvantages

1. Fewer slices per TR (adding a saturation pulse prolongs effective interval)


2. Higher SAR due to more RF energy being applied


3. Requires homogeneous magnet (shimming takes time)


4. Requires uniformly shaped body part ( doesn't work well at base of neck, crook of ankle,etc.)


5. Not recommended with field of view higher than 30 centimeters (unreliable) ( edges of anatomy less well saturated due to distance from ISO Center)


6. Works poorly at lower Fields due to less difference in fat frequency


7. SNR drops

What are 4 main points for fat suppression method 2: STIR