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26 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What does rouleaux formation indicate?
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This is the histological equivalent of increased ESR
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Can a patient with MGUS have a Bence-Jones protein?
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No, this suggests leukemia
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Which immunoglobulin is produced in Waldenstrom's macroglobulinemia?
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IgM
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W = upside down M
Also, it is a MACROglobulinemia. Which Ig is the biggest one? |
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Where in the colon are the polyps found in a patient with HNPCC?
-Proximal or distal? -Ascending or descending? |
Proximal = Asceding = R-sided
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Patient presents with severe postoperative bleeding. On peripheral smear, he has abmormally large platelets. Assays reveal that these platelets that cannot bind vWF. Dx?
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Bernard-Soulier syndrome
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Pt has signs of both platelet dysfunction and hemophilia. Dx?
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von Willebrand disease
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What is the most common form of von Willebrand disease?
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Type I (heterozygote)
Type III is less common and is the homozygote. |
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What is the treatment for Type I and Type IIa vWD?
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Desmopressin -> stimulates release of vWF stores.
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Patient develop cataracts and DVTs following treatment for breast cancer. What caused this?
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Tamoxifen side effects. Also causes menopause.
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What two valvular heart diseases can be caused by carcinoid syndrome?
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Tricuspid regurge
Pulmonic stenosis |
Both cause elevated JVP
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Sickle cell patient has LUQ pain and anemia. Dx?
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Splenic sequestration syndrome
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Red blood cells have basophilic stippling. Dx?
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Lead poisoning
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Causes of microcytic hypchromic anemia?
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T halassemia
I ron Deficiency C hronic Disease S ideroblstic Anemia |
Mnemonic: TICS
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Patient with sickle cell disease develops a syndrome similar to lobar pneumonia. What is this called?
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Acute Chest Syndrome (Infarction)
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Caused y infarction
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Which virus can cause an aplastic anemia in a person with sickle cell disease?
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B19 virus
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A Greek patient develops jaundice whenever he eats fava beans. Dx? Inheritance?
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GPD deficiency (favism)
X-linked, but females are still affected due to lyonization. |
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Patient develops petechiae. Lab reveals extremely low platelet count. Dx?
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ITP (Autoimmune platelet destruction)
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Patient develops autoimmune hemolytic anemia and ITP. Eponym?
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Evan's syndrome
Could also be TTP |
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Patient develops thrombocytopenic thrombotic purpura. What symptoms might he display? (5)
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F ever
A utoimmune Hemolytic Anemia T hrombocytopenia R enal dysfunction N euro lesions (infarcts) |
Mnemonic: FAT RN
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Patient has permanent left-shift, even in the absence of inflammation. Dx?
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Pelger-Huet anomaly
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How specific is LDH for Hodgkin's lymphoma?
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Not very. It is more of a product of tissue turnover than anything else.
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What cancers are associated with CEA? (2)
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Colon cancer
Breast cancer |
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What cancer is associated with CA-125?
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ovarian cancer
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What is a tumor marker for multiple myeloma?
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B2-microglobulin
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Pt has recurrent venous thromboses and hemolysis. UA reveals hemosiderinuria. Dx?
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Paroxysmal noctural hemoglobinuria
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What are the two main lab tests for PNH?
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Acid hemolysis test
Sugar-water test |
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