Phys Test3

Front 1

Stimuli (3) that cause endothelial cells to produce endothelial derive relaxing factor aka

Back 1

1. Bradykinin, stretch, acetylcholine
2. NO

Front 2

NO causes and is derived from

Back 2

vasodilation
endothelial cells

Front 3

Prostacyclin is produced and causes

Back 3

endothelial cells
(inhibits platelet aggregation) and promotes vasodilation

Front 4

Endothelin1 cayses and is produced

Back 4

most potent vasoconstrictor agent known
produced and secreted by endothelium
constricts vascular smooth muscle (intense vasoconstriction of coronary arteries)

Front 5

Thromboxane causes and is produced

Back 5

platelet aggregation and vasoconstriction
produced in platelets

Front 6

Histamine causes and is produced

Back 6

Ateriolar dilation, increased capillary permeability, tissue edema (decrease venous return), contraction of visceral smooth muscle
Stored in granules

Front 7

NE is produced and causes

Back 7

stored in granules in presynaptic terminals of chromaffin cells in the adrenal medulla
causes stimulation of alpha 1 receptors in arterioles (vasoconstriction)

Front 8

EPI is produced and causes

Back 8

Is produced and stored in chromaffin cells in the adrenal medulla
it causes stimulation of alpha1 receptors to cause vasoconstriction

Front 9

Angiotensis II is produced and causes

Back 9

produced by activation of RRAS
it is an extremely potent vasconstricting agent of arterioles & acts on them to increase TPR

Front 10

Vasopressin is produced and casuses

Back 10

stored in vesicles at nerve endings
Extremely (2nd most) potent endogneous vasoconstrictor
-during hemmorhage it restores Pa to normal

Front 11

Bradykinin is formed and causes

Back 11

formed in circulation
-causes arteriolar dilation, increased capillary permeability, contraction of visceral smooth muscle.

Front 12

Stimulators of endothelin1 secretion

Back 12

Angiotensin II
Catecholamines
Hypoxia
Shear Stress

Front 13

Inhibitors of endothelin1 secretion

Back 13

NO
Prostacyclin