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32 Cards in this Set

  • Front
  • Back

- What is Osteoarthritis (OA) also known as?


- Is it a primary or secondary disease? (What is the difference between the two?


- How many area affected?



- degenerative joint disease


- Can be both (Primary = no cause is known, secondary = a cause is known (ex: trauma, infection)


- 27 million, most common rheumatic disease

- What are common risk factors? (6)


- What two groups are most at risk?


- Does it typically affect individual joints, or groups of joints?


- Is it inflammatory?

- heredity, obesity, anatomic joint abnormality, injury, reduced muscle strength, work/leisure leading to overuse of joints


- Those over the age of 65 and females


- Individual joints, typically on dominant side (ex: you can have it in one knee and not the other)


- OA itself is non-inflammatory, though inflammation caused by joint damage is common

- What is the process leading to OA

Two Steps:


1) Breakdown of articular cartilage in joints, causing softening and stiffening; then cartilage wears away causing bone on bone contact (painful, causes crepitus)


2) Reactive bone formation of osteophytes (bone spurs) where ligaments and capsule attach to bone (bone thickens); bone loses its normal shape; cysts form

What are symptoms of Osteoarthritis

- Morning stiffness (less than 30 min)


- Crepitus: audible/palpable crunching or popping in joint caused by irregular cartilage surfaces


- Joint pain


- Gelling: stiffness after periods of inactivity


- Joint enlargement and/or deformity


- Clinical symptoms: pain with barometric pressure changes, "i can tell it's going to rain today"



- Osteoarthritis diagnosis (3 ways)


- What criteria for diagnosis do some doctors adhere to?

-1 Patients history is taken and physical exam is done by physician
- 2 X-ray to confirm clinical diagnosis. Will show osteocyte formation at the joint margin, joint narrowing, subchondral bone sclerosis
- 3 MRI can provide closer look at joint da...

-1 Patients history is taken and physical exam is done by physician


- 2 X-ray to confirm clinical diagnosis. Will show osteocyte formation at the joint margin, joint narrowing, subchondral bone sclerosis


- 3 MRI can provide closer look at joint damage




- Some doctors adhere to specific criteria for diagnosis, such as American college of Rheumatology Criteria

How is osteoarthritis medically managed? (7)
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Analgesic agents
- Corticosteroids
- Disease-Modifying Antirheumatic Drugs
- Biological Response Modifiers
- Surgery, such as  joint replacement, arthroscopic joint debridement, cartilage grafts, ...

- Non-steroidal anti-inflammatory drugs (NSAIDs)


- Analgesic agents


- Corticosteroids


- Disease-Modifying Antirheumatic Drugs


- Biological Response Modifiers


- Surgery, such as joint replacement, arthroscopic joint debridement, cartilage grafts, joint fusion


- Ergonomic evaluation

- Define systemic


- Define auto-immune

- Affects more than just one area (ex: joints, heart, eyes, etc.


- Body attacks itself, destroys tissues

-What is rheumatoid arthritis (high level)?


- Who is at the highest risk (2)


- About how many Americans are affected by it?



- Chronic, systemic auto-immune inflammatory condition, where synovial tissue secretes matrix-degrading enzymes "pannus"  into synovial fluids, which attacks the joint lining causing synovitis 
- People between 40-70 years old and females
- 1.5 ...

- Chronic, systemic auto-immune inflammatory condition, where synovial tissue secretes matrix-degrading enzymes "pannus" into synovial fluids, which attacks the joint lining causing synovitis


- People between 40-70 years old and females


- 1.5 million americans per year

- What are symptoms of Rheumatoid arthritis?

- MAIN: Joint swelling due to excess synovial fluid, enlargement of synovium and thickening of joint capsule. This weakens the joint capsule and stretches ligaments and tendons attached.


- Secondary: Fatigue, Red/hot/swollen/stiff joints, symmetrical joint pain (pain in same joint on both sides), fever, anemia, weight loss, limited independence with ADL/IADL, depression, pulmonary hypertension, renal dysfunction, gastrointestinal bleeding, pericarditis, chest pain, SJOGREN's Syndrome, skin rashes

- How is RA diagnosed

- Mostly by Rheumatoid Factor Antibody (70-90% of those with it have it)


- High erythrocyte sedimentation rate (indicates presence of inflammatory process)


X-ray: shows progressive joint destruction

- What is the American College of Rheumatology Criteria for having RA

- Demonstrate 4 of the following:


1. Morning stiffness


2. Arthritis of three or more joint areas


3. Arthritis of hand joints (swelling)


4. Symmetrical arthritis


5. rheumatoid nodules


6. Serum rheumatoid factor


7. Radiographic changes

-How does RA typically affect the joints?
- Who is the best person to refer someone to who may have RA

-How does RA typically affect the joints?


- Who is the best person to refer someone to who may have RA

- Process IS symmetrical, however one side can be affected more than another 
- Joint deformities occur in about 33% of the people diagnosed w/ RA
- Best person is Rheumatologist, not general practitioner

- Process IS symmetrical, however one side can be affected more than another


- Joint deformities occur in about 33% of the people diagnosed w/ RA


- Best person is Rheumatologist, not general practitioner

- What is the process of RA

- Process varries


- 20% have single episode than remission (monocyclic)


- Most experience a series of flares than remission(Polycyclic)


- Some experience unremitting increase in severity of symptoms (progressive)

What are the two stages of disease process that the American College of Rheumatology Classifies RA

- Stage 1: Early: no destructive changes on x-ray but osteoporosis may be present


- Stage 2: Moderate: x-ray shows osteoporosis and possibly subchondral bone and/or cartilage destruction; limited joint mobility, muscle atrophy, possible nodules and tenosynovitis


- Stage 3: Severe: X-ray evidence of cartilage and bone destruction, soft tissue lesions plus stage 2 criteria


- Stage 4: Terminal: Fibrosis or bony anklyosis plus Stage III criteria

What are some common deformities with Rheumatoid Arthritis -late stage (3)

What sort of RA condition are we seeing here?
What sort of RA condition are we seeing here?
Wrist Subluxation (partial dislocation of the wrist)

- Is there a cure for RA?


- What type of medical treatment is given for RA (10)?

- No cure


- Treatment


1.) Reduce pain, swelling, fatigue


2.) Improve joint function/minimize deformity (deformity is hard to correct once its happening)


3.) Prevent disability and morbidity (disease)


4.) Maintain physical, social and emotional function while minimizing long-term toxicity from medications


5.) Medication (managed by rheumatologist)


6.) NSAIDS (rarely used alone, reduce joint pain/swelling, don't alter disease progression)


7.) Corticosteroids - awesome, but bad side effects


8) DMARDS (disease-modifying anti-rheumatic drugs) - used early to alter disease course


9.) Biologic drugs - when DMARDS don't work


10.) Surgery

- What is fibromyalgia


- How many are affected/who is most common group affected/what is peak onset


- What are common symptoms that occur together

- Common musculoskeletal illness


- 5 mill Americans/women/40-55 yrs old


1.) Decreased pain threshold or tender points 2.) incapacitating fatigue 3.) Widespread pain 4.) Anxiety depression

What are other common symptoms of fibromyalgia

What are fibromyalgia points of pain?

- What does the American College of Rheumatology define as the fibromyalgia diagnostic criteria?


- How long may symptoms be present for?


- What are some physical symptoms associated with fibromyalgia? This are what brings a patient to OT, they don't know they have FM/a



- Trigger finger, tendonitis, joint sprains, nerve impingement, bone fractures

- What does the test for fibromyalgia (FM/a) look for?


- What are common medications used for treating it?

- White blood chemokine and cytokine patterns. People with FM/a have deregulated patterns of this.


1.) Lyrica - nerve pain


2.) Cymbalta and Savella (serotonin and norepinephrine reuptake inhibitors SNRIs


3.) Antidepressents

- What theories exist about the etiology of FM/a

unknown- Cause is unknows, many theories exist


- Hormonal or chemical imbalances/neuroendocrine abnormalities disrupt how the nerves signal pain


- Traumatic event or chronic stress can increase susceptibility


- Lack of sleep


- Many call it a "somatization disorder" (mental, in the person's head)


- Probably result of multiple causes



- Might fibromyalgia present itself


- Is there a cure?


- What does an OT look for in their evaluation of someone with a Rheumatic disease?

- Client history with illness and medical mgmt


- Occupational history, degree of debility w/ ADL and IADL


- Activity diary


- Cognitive, psychological and social status


- Clinical status (ex: inflammation, ROM, strength, hand function, stiffness, pain, sensations, joint instability)

OT Intervention: Rheumatic Disease


- What can be done to relax muscle spasm resulting in joint dysfunction


- Can joint mobilization be done?


- Would someone with FM/A want to use a myofascial releases or trigger point release


- Are modalities good for pain relief? What are some precautions?

- Soft tissue mobilization and stretching


- Minimal with OA and FM/a, but not with RA due to disease process


- Myofasical due to hypersensitivity to touch


- Yes, but heat shouldn't be used with significant inflammation, and cold shouldn't be used with RA

- What therapeutic exercise is good for people with rheumatic disease? (what is best type)?


- What is essential for success of therapeutic exercise?


- What is a precaution?

- strengthening and aerobic/AROM is best - with pain tolerance


- Home exercise programs


- Pain lasting 1-2 hours after exercise indicate need to decrease intensity of program

- Is splinting good for people with rheumatic disease? What type?


- What does splinting require?


- What is the wearing schedule?

- Yes, for inflammation and joint immobilization (static)
- Doctors orders
- Varies based on purpose and degree of inflammation

- Yes, for inflammation and joint immobilization (static)


- Doctors orders


- Varies based on purpose and degree of inflammation

- Why is education important for people with rheumatic disease?
- So they know disease progression, can adjust their life based on progression and to know the importance of doing OT
What are important precautions when dealing with rheumatic disease

- Respect pain, balance activity and rest,


- Use larger, stronger, non-affected joints when possible


- Avoid staying in one position for long


- Use joints in good alignment


- Maintain proper weight


- Hands: avoid tight grasp, use both hands, avoid repetitive activities, avoid pressure to tip of thumb


- Simplify daily activities


- Do ergonomic analysis for home and work environment

What works/doesn't work with people with


- Fibromyalgia


- Rheumatoid Arthritis


- Osteoarthritis


- What affects any therapy with these patients?

- Stretching for reduce muscle spasms/manual therapy - cant tolerate


- splinting-prevent deformity/manual therapy or cold packs due to nodules and joint destruction


- strengthening - reduces pain/cold pacs




- inflammation - can make therapy non productive

What does evidence say about


- Fibromyalgia


- Osteoarthritis


- RA

- Aerobic exercise and patient education best


- Increased physical activity and strengthening


- Aerobic capacity - people with RA can increased aerobic capacity but not likely muscle strength