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262 Cards in this Set

  • Front
  • Back
arteries
large vessels that carry blood away from heart

lined with connective tissue, muscle tissue, elastic fibers, lined with endothelium
Why are arteries elastic?
To force a steady flow of blood, smoothing out the beating of the heart
arterioles
smaller branches of arteries
capillaries
walls comprised of a single layer of endothelium

thin walls allow passage of oxygen & nutrients & waste to/from tissue cells
venules
collect waste-filled deoxy blood from capillaries
vein
conduct blood to heart

thinner than arteries, less elastic tissue
muscle pump
as muscles contract, blood is milked from tissues, into the veins, and through the veins to the heart
valves
in veins and heart to prevent backflow of blood
pulmonary vs systemic circulation
arteries go away from the heart
pulmonic: heart → lungs (deoxygenated)
systemic: heart → body (oxygenated)

veins conduct blood to the heart
pulmonic: lungs → heart (oxygenated)
systemic: heart → body tissues (deoxygenated)
venae cavae
2 large veins that convey blood from venules to heart
Blood circulation
superior & inferior venae cavae
right atrium
tricuspid valve
right ventricle
pulmonary (semilunar) valve
pulmonary artery
lung capillaries
pulmonary vein
left atrium
mitral (bicuspid) valve
left ventricle
aortic (semilunar) valve
aorta
(coronary arteries branch off)
ascending aorta
aortic arch
descending aorta
arterioles
capillaries
venules
venae cavae
What is the thickest-walled part of the heart?
Left ventricle

must be much stronger to pump with enough force to sustain systemic pressure
atria
upper chambers
right: receive blood from heart
left: receive blood from lungs
ventricles
lower chambers
right: sends blood to lungs
left: sends blood to body
carotid artery
supplies blood to head & neck
pulse
axillary artery
armpit
brachial artery
antecubital space
pulse
radial artery
lateral portion of the front of the wrist
pulse
popliteal artery
popliteal region (back of the knee)
pulse
dorsalis pedis artery
lateral superior foot
pulse
posterior tibial arteriy
near medial malleolus
pulse
femoral artery
groin, in the fold created by hip flexion
pulse
renal artery
to kidneys
abdominal aorta
serves abdomen & lower body
splenic artery
spleen
thoracic aorta
serves chest
semilunar valves
between ventricle & blood vessel

aortic: left ventricle → aorta
pulmonary: right ventricle → pulmonary artery
cuspid valves
between atria & ventricles

tricuspid: right
bicuspid (mitral): left

(t is closer to r, m is closer to l)
septum
partition the heart's chambers
plural: septa
interatrial septum
separates atria into left/right
interventricular septum
muscular wall that separates ventricle into left/right
What are the 3 layers of the heart?
from deep to superficial

endocardium
myocardium
pericardium
endocardium
inner-most layer of the heart
smooth layer of endothelial cells
myocardium
middle layer of the heart
thickest, muscular
pericardium
visceral pericardium adheres to the heart & folds over on itself to form the parietal pericardium

pericardial fluid (serous fluid) secreted between them lubricates to reduce friction as the heart beats
2 phases of heart beat
diastole
systole
diastole
relaxation

as ventricle walls relax & blood flows into heart from venae cavae & pulmonary veins

tricuspid & mitral valves open
systole
contraction

as ventricular walls contract, blood enters pulmonary artery & aorta

aortic & pulmonary valves open
murmur
abnormal swishing sound as blood flows through valves caused by improper valve closure
SA node
sinoatrial node

pacemaker of the heart

small region of specialized muscle tissue in posterior portion of right atrium

originates electrical impulse of the heart

causes atrial walls to contract & force blood through ventricles
AV node
atrioventricular node

receives electrical signal from SA node, passes it to atrioventricular bundle

This book incorrectly states that it transmits the signal immediately. One function of the AV node is to delay the signal by ~0.1 s (Physiology of Sport and Exercise, 5th ed. ISBN: 9780736094092, Human Anatomy & Physiology, 8th ed. ISBN: 9780805395693)

located in inferior interatrial septum
atrioventricular bundle
aka bundle of His ('hiss')

located in interventricular septum

divides bundle into left & right bundle branches
right & left bundle branches
conduction myofibers that extend through ventricular walls

contract on stimulation
ECG
aka EKG
electrocardiogram

detects electrical changes in the heart muscle as it beats
deflection
waves depicted on ECG

P
QRS
T
NSR
normal sinus rhythm

60-100 bpm
P wave
diastole

ventricles filling, atrial contraction, atrial depolarization
QRS complex
ventricular depolarization & contraction

systole
T wave
ventricular repolarization

systole
sphygmomanometer
device to measure BP

rubber bag inside cloth cuff that wraps around upper arm

inflation compresses brachial artery

pressure released slowly

systole measured at first sound
diastole measured when sounds change from loud to soft
blood pressure
force the blood exerts on arterial walls
BP expressed as
systolic / diastolic, in mm Hg
aorta
largest artery in the body

heart → systemic circulation
CO₂
carbon dioxide

waste gas released by body cells
transported via veins to the heart
from heart to lungs via pulmonary artery
exhaled from the lungs
coronary arteries
blood vessels that branch from aorta immediately above aortic valve to carry oxygen-rich blood to the heart
artificial cardiac pacemaker
electronic apparatus implanted in chest to stimulate heart muscle that is weak & not functioning
pulse
heart beat as felt through arterial walls
angi/o
vessel

angiogram, angioplasty
aort/o
aorta

aortic stenosis
arter/o, arteri/o
artery

arteriosclerosis
ather/o
yellowish plaque

atherosclerosis
atherosclerosis
form of arteriosclerosis where atheromas (deposits of yellow plaque) are find within lining of artery
atri/o
atrium
brachi/o
arm

brachial artery
cardi/o
heart

cardiomegaly: enlargement of heart
tachycardia
tachy- fast
cardi/o heart

heart rate > 100 bpm
cardiomyopathy
cardi/o heart
my/o muscle
-pathy disease/emotion

disease of the heart muscle
cholesterol/o
cholesterol

a lipid substance
hypercholesterolemia
hyper- above normal, excessive
cholesterol/o cholesterol
-emia blood condition

condition in which there is excessive cholesterol in the blood
coron/o
heart
coronary arteries
coron/o: heart
-ary: pertaining to

coronary arteries descend over heart like a crown
cyan/o
blue
cyanosis
cyan/o: blue
-osis: condition, usually abnormal

bluish discoloration of skin associated with low blood ox
myx/o
mucus
myxoma
myx/o: mucus
-oma: tumor, mass, fluid collection

benign tumor derived from connective tissue with cells embedded in soft mucoid stromal tissue

rare, most often in left ventricle
ox/o
oxygen
hypoxia
hypo-: below normal, deficient, below, under
ox/o: oxygen
-ia: condition

condition in which blood ox is below normal
pericardi/o
pericardium
pericardiocentesis
pericardi/o: pericardium
-centesis: surgical puncture to remove fluid

removal of pericardial fluid from between the pericardium layers
phleb/o
vein
phlebotomy
phleb/o: vein
-tomy: process of cutting

cutting open vein, usually to remove blood
thrombophlebitis
thromb/o: clot, clotting
phleb/o: vein
-itis: inflammation

inflammation of a vein in conjunction with a clot formation
rrhythm/o
rhythm
arrhythmia
a-: no, not, without
rrhythm/o: rhythm
-ia: condition

condition without normal rhythm

dysrhythmia also used
sphygm/o
pulse
sphygmomanometer
sphygm/o: pulse
manometer: device to measure pressure
steth/o
chest
stethoscope
steth/o: chest
-scope: instrument for visual examination

stethoscope is actually used with the ears rather than the eyes
auscultation
listening to sounds within the body, usually with a stethoscope
thromb/o
clot
thrombolysis
thromb/o: clot
-lysis: breakdown, separation, destruction, loosening

breaking up of a clot
valvul/o, valv/o
valve
valvuloplasty
valvul/o: valve
-plasty: surgical repair

balloon-tipped catheter dilates a cardiac valve
mitral valvulitis
valv/o: valve
-itis: inflammation

inflammation of mitral valve
vas/o
vessel
vasoconstriction
vas/o: vessel
construction: to tighten or narrow

to tighten the vessels
vascul/o
vessel
vascular
vascul/o: vessel
-ar: pertaining to

pertaining to a vessel
ven/o, ven/i
vein
venous
ven/o: vein
-ous: pertaining to

pertaining to a vein
venipuncture
ven/i: vein
puncture:

puncturing a vein for phlebotomy or to start an IV infusion
ventricul/o
ventricle
interventricular septum
inter-: between
ventricul/o: ventricle
-ar: pertaining to

septum that is between the ventricles
bradycardia & heart block
failure of proper conduction of impulses from SA node through AV node to atrioventricular bundle
biventricular pacemaker
treats delays & abnormalities in ventricular contractions

enables ventricular synchrony
flutter
rapid but regular contractions, usually of the atria

up to 300 bpm
fibrillation
very rapid, random, inefficient, irregular contractions of the heart

≥350 bpm
palpitation
uncomfortable sensation in chest from missed heartbeat

symptom of fibrillation
AF
a-fib

atrial fibrillation

most common type of cardiac arrhythmia
types of AF
paroxysmal: periodic & episodic
permanent / persistent: continues indefinitely
VF
v-fib

ventricular fibrillation

electrical impulses move randomly throughout ventricles

may be possible to interrupt with defibrillation (application of electrical shock)
drugs to manage VF
digoxin

beta-blockers

calcium channel blockers
ICD
implantable cardioverter-defibrillator

small electrical device implanted inside chest near clavicle to sense arrthmias & terminate them with an electric shock
AED
automatic external defibrillator

used in emergencies to reverse VF
catheter ablation
destruction of tissue causing arrhythmia via radiofrequency energy delivered from tip of catheter inserted through blood vessel into heart
congenital heart disease
abnormalities in the heart at birth
CoA
coarctation of the aorta

congenital narrowing of aorta
PDA
patent ductus arteriosus

passageway (ductus arteriosus) between aorta & pulmonary artery remains open (patent) after birth
septal defects
congenital defects of the septa

small holes in the walls between the atria or ventriles
heart-lung machine
relieves heart & lungs of pumping & oxygenating functions during heart surgery
tetralogy of Fallot
(Fallot like fallow, but with accent on 2nd syllable)

congenital malformation with four (tetra-) distinct heart defects

pulmonary artery stenosis (pulmonary artery narrow or obstructed)

ventricular septal defect (large hole between ventricles)

shift of aorta to the right (aorta overrides interventricular septum to be filled with blood from right aorta)

hypertrophy of right ventricle (myocardium works harder to pump blood through narrowed pulmonary artery)
TGA
transposition of great arteries

congenital defect in which pulmonary artery arises from left ventricle & aorta from right ventricle
CHF
congestive heart failure

heart is unable to pump its required amount of blood

symptoms: shortness of breath, exercise intolerance, fluid retention, pulmonary edema, swelling of legs & feet
CHF types
systolic, diastolic
systolic CHF
left ventricular dysfunction results in low ejection fraction
diastolic CHF
heart is less compliant when filling with blood

fluid backs up into lungs & other parts of body

hypertension is most common cause
pulmonary edema
fluid accumulation in lungs
LVAD
left ventricular assist device

booster pump implanted into abdomen with a cannula inserted into ventricle
CHF drugs
ACE inhibitors (angiotensin-converting enzymes)
beta-blockers
spironolactone
digoxin

goal is to promote fluid loss
CAD
coronary artery disease

disease of the arteries surrounding the heart
myocardial infarction
heart attack
infarct
dead area of myocardial tissue
ischemia
decreased blood flow
ACS
acute coronary syndrome

conditions caused by myocardial ischemia (not enough blood flow to myocardium)

unstable angina & MI consequential to plaque rupture in coronary arteries
types of ACS
MI: myocardial infarction

Unstable angina
chest pain at rest or chest pain of increasing frequency
drugs for ACS
anticoagulants & antiplatelet agents
nitroglycerin
vasodilator
increases coronary blood flow, reduces BP

venodilator
reduces venous return, decreases myocardial O₂ consumption
aspirin
prevent platelet clumping
beta-blockers
reduce force & speed of heartbeat, lower BP

drug used to treat angina, hypertension, arrhythmias

blocks action of epinephrine at receptor cites on cells, slowing the heartbeat
ACE inhibitors
reduce high BP & risk of future MI

antiotensin-converting enzyme inhibitor

blocks conversion of angiotensin I to angiotensin II, causing blood vessels to dilate
calcium channel blockers
relax muscles in blood vessels

used to treat angina, HTN

dilates blood vessels by blocking influx of Ca²⁺ into muscle cells lining vessels
statins
lower cholesterol
CABG
coronary artery bypass grafting

treatment for CAD involving replacement of occluded vessels

arteries & veins anastomosed to coronary arteries to detour around blockages
PCI
percutaneous coronary intervention

catheterization with balloons & stents to open occluded coronary arteries
endocarditis
endo-: in, within
cardi/o: heart
-itis: inflammation

inflammation of the inner lining (endocardium) of the heart
hypertensive heart disease
high BP affecting the heart

results from narrowed arterioles which increase arterial pressure

left ventricular hypertrophy follows because it has to pump harder to overcome increased resistance
MVP
mitral valve prolapse

improper closure of mitral valve

diagnosed with midsystolic click on auscultation
bruit
abnormal blowing or swishing sound heard on auscultation of an artery or organ
thrill
vibration felt on palpation of chest, often accompanies murmur
pericarditis
pericardi/o: pericardium
-itis: inflammation

inflammation of the pericardium
cardiac tamponade
compression of heart caused by collection of fluid in pericardial cavity
rheumatic heart disease
heart disease caused by rheumatic fever
vegetations
clumps of platelets, clotting proteins, microorganisms, and RBC's on diseased heart valves
mitral stenosis
tightening of mitral valve
aneurysm
aneurysm/o: widened blood vessel

local widening of arterial walls
more common in aorta

As widening occurs, plaque collects & eddies form
plaques & clots may break off to flow downstream to narrower areas, occluding downstream vessels

Stress of eddies causes further widening
widening thins & weakens arterial walls, could rupture
berry aneurysm
aneurysm of small vessels in brain

treated with occlusion of the vessel with small clips
treatment of larger aneurysms
aneursym resected, synthetic graft sewn within affected vessel
DVT
deep vein thrombosis

thrombus forms in large vein, usually a lower limb
pulmonary embolism
clot travels to lung, may result from DVT
HTN
hypertension

essential hypertension: high BP with no identifiable cause
secondary: high BP due to an associated lesion
PAD
peripheral artery disease

blockage of arteries carrying blood to legs, arms, kidneys, other organs
intermittent claudication
pain, tension, and weakness in leg after walking has begun; absent at rest
embolic protection devices
parachute-like filters used to capture embolic debris during stenting
Raynaud disease
(ray-no' long a, long o)

recurrent episodes of pallor & cyanosis primarily in fibers & toes
Raynaud phenomenon
similar to Raynaud disease: condition of arterial insufficiency but secondary to arterial narrowing from other conditions
varicose veins
abnormally swollen or twisted veins, usually in the legs

valves fail, allowing blood to pool in superficial veins
hemorrhoid
hem/o: blood
-rrho: flow
-oid: resembling

varicose vein in anal / rectal region
angina (pectoris)
chest pain due to myocardial ischemia

ischemia
isch/o: hold back, back
-emia: blood condition

myocardium isn't supplied enough blood
cardiac arrest
sudden, unexpected stoppage of heart action
sudden cardiac death
digoxin
drug that treats arrhythmias & strengthens heartbeat
embolus
clot or other substance that travels to a distant location & suddenly blocks a blood vessel

plural: emboli
infarction
area of dead tissue
occlusion
closure of blood vessel due to blockage
PVC
premature ventricular contraction
patent
open

e.g. patent airway
pericardial friction rub
scraping or grating heard on auscultation of heart, suggestive of pericarditis
petechiae
small pinpoint hemorrhages
statins
drugs to lower blood cholesterol
BNP test
measures brain natriuretic peptide in blood

elevated with heart failure
cardiac biomarkers
chemical measured in blood as evidence of heart attack

cTnI: troponin-I
cTnT: troponin-T

troponin is released from heart muscle into circulation after myocardial injury
lipid profile
lipid tests

measures cholesterol & triglycerides (fats) in a blood sample

saturated: increase blood cholesterol
polyunsaturated: decrease blood cholesterol
hyperlipidemia
hyper-: exessive, above normal
lipid/o: fat
-emia: blood condition

too much fat in the blood
lipoprotein electrophoresis
lipoproteins are physically separated & measured in a blood sample

e.g. HDL, LDLd
LDL
low-density lipoprotein

"bad cholesterol"
associated with atherosclerosis

reference level: < 130 mg/dL
HDL
high-density lipoprotein

reference level: 70 mg/dL
angiography
x-ray imaging of blood vessels after injection of contrast material
arteriography
x-ray imaging of arteries after injection of contrast via catheter
CTA
computed tomography angiography

3d x-ray image of heart & coronary arteries using CT
DSA
digital subtraction angiography

video equipment & computer produce x-ray images of blood vessels

x-rays taken before & after injection of contrast material
computer compares them, subtracting digital data from the before from the after
EBCT or EBT
electron beam computed tomography

electron beams & CT identify calcium deposits in and around coronary arteries

diagnoses early CAD

risk
0-99: low
100-399: intermediate
>400: high
Doppler ultrasound studies
sound waves measure blood flow within blood vessels

instrument focuses on sound waves on blood vessels, echoes bounce off the RBC's contained within
Duplex ultrasound
combines Doppler & convential ultrasound so physician can image blood vessel structure & measure speed of flow

diagnosis of
carotid artery occlusion, aneurysm, varicose veins, other vessel disorders
ECHO
echocardiography

echoes generated by high-frequency sound waves produce images of the heart, both structure & movement
TEE
transesophageal echocardiography

transducer in esophagus provides ultrasound & doppler info

diagnoses cardiac masses, prosthetic valve function, aneurysms, pericardial fluid
PET scan
positron emission tomography

images show blood flow & myocardial function following uptake of radioactive glucose

detects: CAD, myocardial function, differences between ischemic HD & cardiomyopathy
techneitium Tc 99m sestamibi scan
Technetium Tc 99m sestamibi injected intravenously, taken up in cardiac tissue, detected by scanning

to assess amount of heart muscle damaged in an MI
used with exercise tolerance test (ETT-MIBI)
thallium 201 scan
concentration of radioactive thallium measured to give info about blood supply to heart muscle

infarctions show as cold spots
cardiac MRI
images of the heart produced using radiowave energy in a magnetic field

provides info about: aneurysms, cardiac output, patency of peripheral & coronary arteries
MRA
magnetic resonance angiography

MRI that gives highly detailed images of blood vessels
cardiac catheterization
thin, flexible tube guided into heart via artery or vein

detects pressures & patterns of blood flow in heart

allows injection of contrast material
ECG
electrocardiography

recording of electricity flowing through heart
telemetry
electronic transmission of data

tel/o: distant
metr/o: uterus, measure
-y: condition, process
Holter monitoring
wearing ECG for 24-hour period to detect cardiac arrhythmias
stress test
ETT to determine heart's response to physical exertion
ETT
exercise tolerance test
catheter ablation
brief delivery of radiofrequency or cryosurgery to destroy areas of heart tissue that may be causing arrhythmias
defibrillation
application of brief discharges of electricity to chest

to stop dysrhythmias (VF)
endarterectomy
surgical removal of plaque from inner layer of an artery

endo-: within
arter/o: artery
-ectomy: removal, excision, resection
extracorporeal circulation
circulation managed outside the body

heart-lung machine diverts blood from heart & lungs while heart is repaired
heart transplantation
donor heart transferred to recipient
stent
expandable slotted tube
thrombolytic therapy
drugs to dissolve clots injected into bloodstream of patient with coronary thrombosis

tPA: tissue plasminogen activator
streptokinase

reduce mortality in MI patients by 25%
AAA
abdominal aortic aneurysm
ACLS
advanced cardiac life support

CPR, drugs, defibrillation
ADP blockers
used to prevent cardiovascular-related death, MI, & strokes after stent procedures
AICD
automatic implantable cardioverter-defibrillator
AMI
acute myocardial infarction
ARVD
arrhythmogenic right ventricular dysplasia
AS
aortic stenosis
ASD
atrial septal defect
AV, A-V
atrioventricular
AVR
aortic valve replacement
BBB
bundle branch block
CCU
coronary care unit
Cath
catheterization
CK
creatine kinase

released into blood after injury to heart or skeletal muscle
CPR
cardiopulmonary resuscitation
CRT
cardiac resynchronization therapy

biventricular pacing
CV
cardiovascular
CTNI,cTnI, CTNT, cTnT
cardiac troponin-I
cardiac troponin-T

muscle protein released to blood after MI
DES
drug-eluting stent

stent that slowly release a drug to block cell proliferation
ECMO
extracorporeal membrane oxygenation
EF
ejection fraction

measure of the amount of blood that pumps out of the heart with each beat
EPS
electrophysiology study

electrode catheters inserted into veins & threaded into heart to measure electrical conduction
ETT-MIBI
exercise tolerance test combined with radioactive tracer (sestamibi) scan
IABP
intra-aortic balloon pump

supports patients in cardiogenic shock

cardi/o: heart
-genic: produced by or in

shock produced by or in the heart
LAD
left anterior descending coronary artery
LMWH
low-molecular-weight heparin
LV
left ventricle
LVH
left ventricular hypertrophy

enlargement of left ventricle
MR
mitral regurgitation
MUGA
multiple-gated acquisition scan

radioactive test of heart function
PAC
premature atrial contraction
PDA
patent ductus arteriosus

posterior descending artery
SCD
sudden cardiac death
SOB
shortness of breath
SPECT
single photon emission computed tomography

used for myocardial imaging with sestamibi scans
SSCP
SubSternal Chest Pain
STEMI
ST elevation MI
SVT
supraventricular tachycardia
UA
unstable angina

chest pain at rest or of increasing frequency
VSD
ventricular septal defect
VT
ventricular tachycardia
WPW
Wolff-Parkinson-White syndrome

abnormal ECG pattern associated with paroxysmal tachycardia
LV aneurysmectomy
surgery to remove protrusion of the wall of a lower heart chamber
left carotid endarterectomy
to treat atherosclerotic occlusion of a main artery leading to the head
sclerosing injections & laser treatment
to treat varicose veins
atrial septal defect repair
to treat congenital hole in wall of upper heart chamber
pericardiocentesis
to treat cardiac tamponade
aortic valve replacement
to treat aortic stenosis
pacemaker implantation
to treat heart block
femoral-popliteal bypass graft
to treat peripheral vascular disease