Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
Corynebacterium Diphtheriae
|
Typically occurs in immigrants without vaccine.
Since the vaccine, cases have dropped pseudomembrane-Don't touch because of bleeding or slip "bull neck" |
|
|
Medium you test on if you suspect Corynebacterium Diphtheriae
|
Cysterine-tellurite Loeffler's Medium
|
|
|
Diphtheriae Pathogenicity
|
Diptheria secrets a toxin with
A=active domain B=Binding domain T-Translocation domain The A domain halts protein synthesis and kills the cell |
|
|
What is the diptheria vaccine?
|
Slightly denatured A domain= inactive toxin
Toxoid -antibodies against B domain is created. -When antibodies bind the B unit, the toxin cannot bind, preventing Diphtheria toxin B domain still in tact |
|
|
Epstein-Barr Virus
|
Clinical
Tonsillitis/pharyngitis Extreme Malaise!!! Cervical lymphadenopathy Spleenomegaly (avoid contact sport) atypical T-lymphocytes Test monospot test heterophile anitbodies for sheep RBC Treatment Symptomatic |
|
|
Influenza Virus
structure and symptoms |
Orthomyxovirus
Single stranded (-) RNA Virus Haemagglutinin Neuraminidase Symptoms Fever headache cough body ache runny nose sore throat Superbowl |
|
|
Influenze Drift
|
Annual point mutations
Single stranded RNA make it more susceptible to mistakes and variation to the original code This results in H and N which are still like H1N1 but have little variations in antibody binding etc |
|
|
Influenza Shift
|
Every 10 years
mixed infection ressortment of RNA pieces |
|
|
Reyes Syndrome
|
Neurological complication which occurs when aspirin is given to an individual with the FLU.
|
|
|
Adenovirus
|
Sore throat
Pneumonia Conjunctivitis palpable preauricular lymphadenopathy Extremely common (children) |
|
|
Moraxella Catarrhalis
|
Infection of the middle
Connection to throat results in sore throat Noted for antibiotic resistance |
|
|
Neisseria gonorrhoea
|
gross
|
|
|
Coxsackievirus A
Herpangina (vesicles/ulcerations) |
Vesicles and ulcerations
|
|
|
Arcanobacterium hemolyticum
|
sore throat + scarlatine rash
|
|
|
GABS
How does it infect? What are its virulent factors? How does it evade the immune system? |
Group A Refers to the C carbohydrate Lancefield Antigen A
Mechanism Step 1: Adherence •M Protein, lipoteichoic acid, and protein F oMediated attachment to the fatty acid binding sites in fibronectin oFibronectin cover the epithelial cell surface Step 2:Release of Toxins •Streptolysin O- An enzyme that destroys red and white blood cells giving to its beta-hemolytic state oStreptokinase- activates the proteolytic enzyme plamin which breaks up fibrin blood clots oHyaluronidase- breaks down hyaluronic capsule which protects bacteria from immune system. This aids in spread of bacteria Evading Immune system •M-protein inhibits the activation of complement and protects the organism from phagocytosis •C5a peptidase oDegrades complement component C5a (complement attracts phagocytes to the battlefield) oDestroys the chemotactic signals |
