Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
Trazodone, buproprion
Chemically distinct Often grouped as “heterocyclics |
Older Drug Therapies
|
|
|
Buproprion
|
MOA poorly understood
High doses associated with seizures Aid to smoking cessation |
|
|
Selegiline (Emsam
|
Monoamine oxidase inhibitor in patch form
Considered 3rd or 4th line in therapy until more data becomes available |
|
|
Acute phase
|
6-8 weeks at full therapeutic doses
Aim: remission of symptoms |
|
|
SSRIs
|
Fluoxetine (Prozac), Sertraline (Zoloft), Paroxetine (Paxil), Fluvoxamine (Luvox), Citalopram (Celexa),
Escitalopram (Lexapro) |
|
|
TCAs
|
Amitriptiyline (Elavil), Nortriptyline (Pamelor),
Imipramine (Tofranil), Desipramine (Norpramin), Doxepin (Sinequan), Amoxapine (Asendin) |
|
|
Continuation phase
|
6-9 months at full dose for all patients
Aim: prevent relapse |
|
|
MAO Inhibitors
|
Phenelzine (Nardil), Selegiline patch (Emsam),
Tranylcypromine (Parnate) |
|
|
Maintenance phase
|
1- 2 years or lifelong
Aim: prevent occurrence of future depressive episodes |
|
|
NSRIs
|
Venlafaxine (Effexor), Duloxetine (Cymbalta), Desvenlafaxine (Pristiq)
|
|
|
Mirtazapine (Remeron), Trazodone (Desyrel),
Nefazodone (Serzone), Buproprion (Wellbutrin) |
others
|
|
|
Inhibit enzyme that metabolizes many of neurotransmitters
|
MAO Inhibitors
|
|
|
Represent the standard to which all new drugs are compared
Mainstay of therapy prior to SSRIs |
TCAs
|
|
|
Orthostatic hypotension, mild anticholinergic effects, delayed ejaculation
More common than with any other class Drug interactions Tyramine-containing foods [aged cheese, tap beer, sauerkraut] Sympathomimetics, stimulants, levodopa, meperidine [hypertensive crisis] |
MAO Inhibitors SE
|
|
|
Block norepi and serotonin reuptake sites
|
TCAs
|
