Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/15

Click to flip

15 Cards in this Set

  • Front
  • Back
Trazodone, buproprion
Chemically distinct
Often grouped as “heterocyclics
Older Drug Therapies
Buproprion
MOA poorly understood
High doses associated with seizures
Aid to smoking cessation
Selegiline (Emsam
Monoamine oxidase inhibitor in patch form
Considered 3rd or 4th line in therapy until more data becomes available
Acute phase
6-8 weeks at full therapeutic doses
Aim: remission of symptoms
SSRIs
Fluoxetine (Prozac), Sertraline (Zoloft), Paroxetine (Paxil), Fluvoxamine (Luvox), Citalopram (Celexa),
Escitalopram (Lexapro)
TCAs
Amitriptiyline (Elavil), Nortriptyline (Pamelor),
Imipramine (Tofranil), Desipramine (Norpramin),
Doxepin (Sinequan), Amoxapine (Asendin)
Continuation phase
6-9 months at full dose for all patients
Aim: prevent relapse
MAO Inhibitors
Phenelzine (Nardil), Selegiline patch (Emsam),
Tranylcypromine (Parnate)
Maintenance phase
1- 2 years or lifelong
Aim: prevent occurrence of future depressive episodes
NSRIs
Venlafaxine (Effexor), Duloxetine (Cymbalta), Desvenlafaxine (Pristiq)
Mirtazapine (Remeron), Trazodone (Desyrel),
Nefazodone (Serzone), Buproprion (Wellbutrin)
others
Inhibit enzyme that metabolizes many of neurotransmitters
MAO Inhibitors
Represent the standard to which all new drugs are compared
Mainstay of therapy prior to SSRIs
TCAs
Orthostatic hypotension, mild anticholinergic effects, delayed ejaculation
More common than with any other class
Drug interactions
Tyramine-containing foods [aged cheese, tap beer, sauerkraut]
Sympathomimetics, stimulants, levodopa, meperidine [hypertensive crisis]
MAO Inhibitors SE
Block norepi and serotonin reuptake sites
TCAs