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30 Cards in this Set

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  • Back
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What are the 5 catecholamine drugss?
Epinephrine, NE, Isoproterenol, Dopamin, Dobutamine
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What is the mechanism/selectivity of Epinephrine?
Direct general agonist (a1, a2, b1, b2)
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What are the 4 uses of Epienphrine?
Anaphylaxis, glaucoma (open angle), asthma, hypotension
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What is the mechanism/selectivity of NE?
a1, a2, b1 agonist
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What is NE used for? When would you avoid it?
Hypotension but avoid in pts with renal problems b/c it decreases renal perfusion)
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What is the mechanism/selectivity of Isoproterenol?
b1=b2 agonist
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What is the Isoproterenol used for?
AV block (rare)
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What is the mechanism/selectivity of Dopamine?
D1=D2>b>a agonist
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What are the 2 uses for dopamine?
Shock (increases renal perfusion), heart failure
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What is the mechanism/action of dobutamine?
b1>b2 agonist
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What are the 2 uses of dobutamine?
shock, heart failure
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What is the mechanism of Amphetamine?
Indirect general agonist that releases stored catecholamines
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What are the 3 applications of amphetamines?
Narcolepsy, obesity, ADD
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What is the mechanism of Ephedrine?
Indirect general agonist that releases stored catecholamines
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What are the 3 uses of Ephedrine?
Nasal congestion, urinary incontinence, hypotension
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What is the selectivity of Phenylephrine?
a1>a2 agonist
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What are the 3 uses of Phenylephrine?
Pupil dilator, vasoconstriction, nasal congestion
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What is the selectivity of Albuterol?
b2>b1 agonist
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What is albuterol used for?
asthma
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What is terbutaline used for?
asthma
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What is the selectivity of terbutaline?
b2>b1 agonist
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What is the mechanism of action of cocaine?
Indirect general agonist, uptake inhibitor of NE
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What are the 2 uses/effects of cocaine?
vasoconstriction and local anesthesia
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What is the mechanism of actionof clonidine?
Centrally acting a-agonist, decreases central adrenergic outflow
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What is the mechanism of action of a-methyldopa?
Centrally acting a-agonist, decreases central adrenergic outflow
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What is clonidine used for?
Hypertension, especially with renal disease (no decrease in blood flow to kidney)
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What is a-methyldopa used for?
Hypertension, especially with renal disease (no decrease in blood flow to kidney)
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What happens when NE is given and why?
NE has a>b effectws, have rise in systolic and diastolic BP and relfex bradychardia
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What happens when Epinephrin is given and why?
Epinephrine is non selective, have increase systolic and decrease diastolic pressure, with increase in heart rate
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What happens when Isoproterenol is given and why?
Isoproterenol has b>a effects so have small rise and then fall in systolic pressure and fall in diastolic pressure with a gradual increase in heart rate.
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