Pharmii

Front 1

What are the 5 catecholamine drugss?

Back 1

Epinephrine, NE, Isoproterenol, Dopamin, Dobutamine

Hint 1

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Front 2

What is the mechanism/selectivity of Epinephrine?

Back 2

Direct general agonist (a1, a2, b1, b2)

Hint 2

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Front 3

What are the 4 uses of Epienphrine?

Back 3

Anaphylaxis, glaucoma (open angle), asthma, hypotension

Hint 3

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Front 4

What is the mechanism/selectivity of NE?

Back 4

a1, a2, b1 agonist

Hint 4

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Front 5

What is NE used for? When would you avoid it?

Back 5

Hypotension but avoid in pts with renal problems b/c it decreases renal perfusion)

Hint 5

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Front 6

What is the mechanism/selectivity of Isoproterenol?

Back 6

b1=b2 agonist

Hint 6

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Front 7

What is the Isoproterenol used for?

Back 7

AV block (rare)

Hint 7

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Front 8

What is the mechanism/selectivity of Dopamine?

Back 8

D1=D2>b>a agonist

Hint 8

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Front 9

What are the 2 uses for dopamine?

Back 9

Shock (increases renal perfusion), heart failure

Hint 9

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Front 10

What is the mechanism/action of dobutamine?

Back 10

b1>b2 agonist

Hint 10

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Front 11

What are the 2 uses of dobutamine?

Back 11

shock, heart failure

Hint 11

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Front 12

What is the mechanism of Amphetamine?

Back 12

Indirect general agonist that releases stored catecholamines

Hint 12

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Front 13

What are the 3 applications of amphetamines?

Back 13

Narcolepsy, obesity, ADD

Hint 13

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Front 14

What is the mechanism of Ephedrine?

Back 14

Indirect general agonist that releases stored catecholamines

Hint 14

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Front 15

What are the 3 uses of Ephedrine?

Back 15

Nasal congestion, urinary incontinence, hypotension

Hint 15

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Front 16

What is the selectivity of Phenylephrine?

Back 16

a1>a2 agonist

Hint 16

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Front 17

What are the 3 uses of Phenylephrine?

Back 17

Pupil dilator, vasoconstriction, nasal congestion

Hint 17

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Front 18

What is the selectivity of Albuterol?

Back 18

b2>b1 agonist

Hint 18

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Front 19

What is albuterol used for?

Back 19

asthma

Hint 19

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Front 20

What is terbutaline used for?

Back 20

asthma

Hint 20

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Front 21

What is the selectivity of terbutaline?

Back 21

b2>b1 agonist

Hint 21

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Front 22

What is the mechanism of action of cocaine?

Back 22

Indirect general agonist, uptake inhibitor of NE

Hint 22

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Front 23

What are the 2 uses/effects of cocaine?

Back 23

vasoconstriction and local anesthesia

Hint 23

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Front 24

What is the mechanism of actionof clonidine?

Back 24

Centrally acting a-agonist, decreases central adrenergic outflow

Hint 24

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Front 25

What is the mechanism of action of a-methyldopa?

Back 25

Centrally acting a-agonist, decreases central adrenergic outflow

Hint 25

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Front 26

What is clonidine used for?

Back 26

Hypertension, especially with renal disease (no decrease in blood flow to kidney)

Hint 26

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Front 27

What is a-methyldopa used for?

Back 27

Hypertension, especially with renal disease (no decrease in blood flow to kidney)

Hint 27

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Front 28

What happens when NE is given and why?

Back 28

NE has a>b effectws, have rise in systolic and diastolic BP and relfex bradychardia

Hint 28

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Front 29

What happens when Epinephrin is given and why?

Back 29

Epinephrine is non selective, have increase systolic and decrease diastolic pressure, with increase in heart rate

Hint 29

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Front 30

What happens when Isoproterenol is given and why?

Back 30

Isoproterenol has b>a effects so have small rise and then fall in systolic pressure and fall in diastolic pressure with a gradual increase in heart rate.

Hint 30

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