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26 Cards in this Set
- Front
- Back
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PCN Mechanism of action
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Interfere w/ cell wall synthesis by allowing excess water in which in turn causes the cell to explode
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Natural PCN's
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Penicillin G - for Gram Pos cocci and bacilli
PCN V - Similar to PCN G |
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Extended Spectrum PCN's
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Amoxicillin/Ampicillin - More affective against gram negative bacilli
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Anti Staph PCN's
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Dicolxacillin - Penicillinase resistant. Will not work against MRSA
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PCN Routes of Administration
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PCN G - PO,IV,IM
PCN VK - PO Ampicillin - PO,IM,IV Amoxicillin - PO Augmentin - PO Dicloxacillin - PO |
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Cephalosporin Mechanism of Action
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Bacteriocidal similar to PCN's. More PCNase than PCN's.
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1st Generation Cephalosporin
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Cephalexin (Keflex)
Cefazolin (Ancef) |
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2nd Generation
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Cefotetan (Cefotan)
Cefoxitin (Mefoxin) |
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3rd and 4th Generation
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Ceftriaxone
Cefixime Cefepime Used for wide spectrum gram negative organisms |
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Sulfonamides mechanism of action
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Inhibit growth by retarding folic acid synthesis
Good for gram pos and neg spectrum |
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Sulfonamide routes of Administration
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Silver Sulfadiazine - Topical (Silvadine)
Sulfacetamide sodium- Opthalmic SMZ-TMP - PO,IV Sulfasalazine - PO |
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Macrolides Mechanism of action
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Bacteriostatic through inhibition of protein synthesis
Sometimes bacteriocidal |
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Macrolide Types
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Erythromycin [E-Mycin}(PO,IV,Topical,Opthalmic)
Clarithromycin (PO) [Biaxin] Azithromycin (PO,IV) [Zithromax] |
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Tetracycline Mechanism of action
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Bacteriostatic through inhibition of protein synthesis
Broad spectrum gram pos and neg |
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Tetracycline Types
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Tetracycline (PO,IM,IV)
Doxycycline (PO,IV) Minocycline (PO,IV) |
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Fluoroquinolones MOA
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Bacteriocidal by inhibiting DNA replication of bacteria
Good against gram neg (infectious diarrhea) |
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Fluoroquinolones
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Ciprofloxin (PO,IV) [Cipro]
Levofloxacin (PO,IV) [Levaquin] |
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Misc. antibiotics MOA
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Bacteriostatic that inhibit protein synthesis
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Miscellaneous Types
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Chloramphenicol (IV)
Clindamycin (PO,IV,IM) Gentamycin (Topical,IM,IV,Opthalmic) |
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Amebicides MOA
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microbicidal by inhibiting nucleic acid synthesis
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Amebicide Type
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Metronidazole (Flagyl) [PO,IV]
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Antimalarial MOA
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Disrupts protein synthesis and DNA synthesis
Affects mitochondria |
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Antiviral MOA
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Interfere with viral DNA synthesis
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Antiviral Routes of administration
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Acyclovir- (Topical,PO,IV)
Trifulridine- Ophthalmic |
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Antifungals MOA
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Inhibit ergosterol of fungal cell membranes
Microstatic and microbicidal |
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Antifungal Routes
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Amphoteracin (Topical,IV)
Fluconazole (PO,IV) Itraconazole (Topical,PO) Ketaconazole (PO) Miconazole and Clotrimazole (Topicl) Nystatin (Topical) Terbinafine (Topical,PO) |
