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26 Cards in this Set

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PCN Mechanism of action
Interfere w/ cell wall synthesis by allowing excess water in which in turn causes the cell to explode
Natural PCN's
Penicillin G - for Gram Pos cocci and bacilli

PCN V - Similar to PCN G
Extended Spectrum PCN's
Amoxicillin/Ampicillin - More affective against gram negative bacilli
Anti Staph PCN's
Dicolxacillin - Penicillinase resistant. Will not work against MRSA
PCN Routes of Administration
PCN G - PO,IV,IM
PCN VK - PO
Ampicillin - PO,IM,IV
Amoxicillin - PO
Augmentin - PO
Dicloxacillin - PO
Cephalosporin Mechanism of Action
Bacteriocidal similar to PCN's. More PCNase than PCN's.
1st Generation Cephalosporin
Cephalexin (Keflex)
Cefazolin (Ancef)
2nd Generation
Cefotetan (Cefotan)
Cefoxitin (Mefoxin)
3rd and 4th Generation
Ceftriaxone
Cefixime

Cefepime

Used for wide spectrum gram negative organisms
Sulfonamides mechanism of action
Inhibit growth by retarding folic acid synthesis

Good for gram pos and neg spectrum
Sulfonamide routes of Administration
Silver Sulfadiazine - Topical (Silvadine)
Sulfacetamide sodium- Opthalmic
SMZ-TMP - PO,IV
Sulfasalazine - PO
Macrolides Mechanism of action
Bacteriostatic through inhibition of protein synthesis

Sometimes bacteriocidal
Macrolide Types
Erythromycin [E-Mycin}(PO,IV,Topical,Opthalmic)

Clarithromycin (PO) [Biaxin]

Azithromycin (PO,IV) [Zithromax]
Tetracycline Mechanism of action
Bacteriostatic through inhibition of protein synthesis

Broad spectrum gram pos and neg
Tetracycline Types
Tetracycline (PO,IM,IV)
Doxycycline (PO,IV)
Minocycline (PO,IV)
Fluoroquinolones MOA
Bacteriocidal by inhibiting DNA replication of bacteria

Good against gram neg (infectious diarrhea)
Fluoroquinolones
Ciprofloxin (PO,IV) [Cipro]
Levofloxacin (PO,IV) [Levaquin]
Misc. antibiotics MOA
Bacteriostatic that inhibit protein synthesis
Miscellaneous Types
Chloramphenicol (IV)
Clindamycin (PO,IV,IM)
Gentamycin (Topical,IM,IV,Opthalmic)
Amebicides MOA
microbicidal by inhibiting nucleic acid synthesis
Amebicide Type
Metronidazole (Flagyl) [PO,IV]
Antimalarial MOA
Disrupts protein synthesis and DNA synthesis

Affects mitochondria
Antiviral MOA
Interfere with viral DNA synthesis
Antiviral Routes of administration
Acyclovir- (Topical,PO,IV)

Trifulridine- Ophthalmic
Antifungals MOA
Inhibit ergosterol of fungal cell membranes

Microstatic and microbicidal
Antifungal Routes
Amphoteracin (Topical,IV)
Fluconazole (PO,IV)
Itraconazole (Topical,PO)
Ketaconazole (PO)
Miconazole and Clotrimazole (Topicl)
Nystatin (Topical)
Terbinafine (Topical,PO)