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16 Cards in this Set

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  • Back
This antigen is mos most likely to cause the release of Histamine
IgE
What are three types of release of Histamine
Slow endogenous
Fast Endogenous
Exogenous
What is the most important Histamine receptor in allergic reactions
H1
What are 3 affects of an anaphylactic reaction
vasodilatio/hypotension
Bronchconstriction
epithelial cotraction(capillary permeability and edema)
In general what affect does histamine have on small vessels and end arterioles?

Large arteries and veins?
Dilate

Constrict
What is the primary difference between generation 1 and gen. 2 H1 blockers?
H1 blockers cross the blood-brain barrier and cause sedation
What are 3 peripheral acting emetics
Salt – salt poisoning
H2O2 – stimulates CRT
Syrup of ipecac – inc lacrimation, salivation, bronchial secretions
What are some contraindications for antiemetics
GI infection
GI blockage
GI toxicity
Systemic hypotension
Epilepsy
What are 3 H2 receptor antagonists
Cimetidine
Ranitidine
famotidine
What receptor is inhibitory to gastric motility
Opioid receptor
What antisecretory/cytoprotective effects do Prostaglandins provide?
Inhibit acid secretion
Stimulate mucus and bicarbonate
Enhance local blood flow
What is the major indication for giving Misoprostol (prostaglandins) as an antisecretoery/cytoprotedtant?
Mostly used in patients requiring prolonged NSAID or corticosteroid use, or are under undue stress
What are the clinical signs of post-operative ileus?
abdominal pain, nasogastric reflux, absent
borborygmi, lack of feces production, deterioration of
health
What are the 6 types of prokinetic drugs?
Cholinergic
Adrenergic receptor antagonists
Dopamine antagonists
Serotonin agonists
Motilin agonists
Lidocaine
What receptor does Bethanacol act on and what is the preferred method of administration?
Muscarinic
Oral or Sub Q
What two prokinetic drugs act as antagonists to the dopamine receptor and which would have fewer CNS side effects?
Metoclopramide and domperidone

Domperidone does not cross B/B barrier