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16 Cards in this Set
- Front
- Back
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This antigen is mos most likely to cause the release of Histamine
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IgE
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What are three types of release of Histamine
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Slow endogenous
Fast Endogenous Exogenous |
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What is the most important Histamine receptor in allergic reactions
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H1
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What are 3 affects of an anaphylactic reaction
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vasodilatio/hypotension
Bronchconstriction epithelial cotraction(capillary permeability and edema) |
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In general what affect does histamine have on small vessels and end arterioles?
Large arteries and veins? |
Dilate
Constrict |
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What is the primary difference between generation 1 and gen. 2 H1 blockers?
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H1 blockers cross the blood-brain barrier and cause sedation
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What are 3 peripheral acting emetics
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Salt – salt poisoning
H2O2 – stimulates CRT Syrup of ipecac – inc lacrimation, salivation, bronchial secretions |
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What are some contraindications for antiemetics
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GI infection
GI blockage GI toxicity Systemic hypotension Epilepsy |
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What are 3 H2 receptor antagonists
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Cimetidine
Ranitidine famotidine |
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What receptor is inhibitory to gastric motility
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Opioid receptor
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What antisecretory/cytoprotective effects do Prostaglandins provide?
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Inhibit acid secretion
Stimulate mucus and bicarbonate Enhance local blood flow |
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What is the major indication for giving Misoprostol (prostaglandins) as an antisecretoery/cytoprotedtant?
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Mostly used in patients requiring prolonged NSAID or corticosteroid use, or are under undue stress
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What are the clinical signs of post-operative ileus?
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abdominal pain, nasogastric reflux, absent
borborygmi, lack of feces production, deterioration of health |
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What are the 6 types of prokinetic drugs?
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Cholinergic
Adrenergic receptor antagonists Dopamine antagonists Serotonin agonists Motilin agonists Lidocaine |
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What receptor does Bethanacol act on and what is the preferred method of administration?
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Muscarinic
Oral or Sub Q |
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What two prokinetic drugs act as antagonists to the dopamine receptor and which would have fewer CNS side effects?
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Metoclopramide and domperidone
Domperidone does not cross B/B barrier |
