Pharmacology Test #2A

Front 1

Epinephrine is?

Back 1

Secreted from the adrenal medulla

Front 2

Of drugs or activities used to combat hypertension, which is Poorest choice?

Back 2

Ca++ channel antagonist

Front 3

Diuretics may have all effects Except?

Back 3

Increase the amount of Na+ reabsorbed from the urine

Front 4

In hypertensive dental patients, all statements are correct Except?

Back 4

Administration of opiods for analgesia may increase their BP

Front 5

Class I anti-arrhythmic drugs?

Back 5

Block Na+ Channels

Front 6

All pairs of agents and actions and receptors occur or interact physiologically in normal individuals Except?

Back 6

Epinephrine-dopamine receptors

Epinephrine tends to bind to Beta-2 receptors and dilate smooth muscle.

Front 7

All may be useful in tx of CHF Except?

Back 7

K+ restriction

Front 8

Digoxin exerts its therapeutic effect by inhibiting

Back 8

Heat Na+ K+ ATPase

Front 9

CHF px on digoxin exhibit all of the following Except?

Back 9

They survive longer than px NOT on digoxin
(Avoid Digoxin if you can because it is not a Safe drug)

Front 10

What condition responds to organic nitrates like nitroglycerin?

Back 10

Angina Pectoris

Front 11

In a dental px with angina, all are correct except?

Back 11

The incidence of thrush is increased

Front 12

Ipratropium (ATROVENT)

Back 12

Inhibits muscarinic cholinergic receptors

Front 13

Which property is the major difference between older antihistamines like diphenylhydramine (Benadryl) and the newer antihistamines like laratidine (Claritin)

Back 13

Newer are less sedating

Front 14

Cromolyn sodium (nasalcrom)?

Back 14

Stabilizes mast cells to prevent release of histamine and other inflammatory mediators

Front 15

Niacin at high doses can be used as antihyperlipidemic agent because it?

Back 15

Inhibits lipolysis in adipose tissue

Front 16

With dental px who have airway disease, the practitioner should expect all Except?

Back 16

Increased sensitivity to local anesthetics with or withour epinephrine

Front 17

All are correct statements about px on ACE inhibitors Except?

Back 17

Lower than normal dose should be prescribed if px has hepatic impairment

Front 18

Ion channels have all properties Except?

Back 18

They use ATP to provide energy for ion movement

Front 19

Of following analgesics, which is best for perioperative analgesia in px with CKD?

Back 19

Fentanyl

Front 20

Losartan or Ibesartan administration reduces blood pressure by blocking or inhibiting?

Back 20

Angiotensin II receptors

Front 21

Primary tx for CKD is administration of?

Back 21

Angiotensin receptor antagonist

Front 22

Physiologically, in human, which of the following is Incorrect?

Back 22

Norepinephrine predominantly inhibits B2-adrenergic receptors in the heart

Front 23

All are pairings of drugs with adverse/physiologic effect are correct Except?

Back 23

Beta-blockers --tachycardia
Beta-Blockers are used to treat tachycardia

Front 24

Which drug combo is recommended in most px for initial hypertension treatment?

Back 24

A diuretic and Beta-blocker

Front 25

Diuretics are used to tx CHF because?

Back 25

Decrease plasma volume

Front 26

Statins such as mevacor and lipitor are antihyperlipidemic agents because they directly inhibit?

Back 26

Cholesterol synthesis

Front 27

Which agent is the preferred tx for acute asthmatic attack?

Back 27

Inhalation of albuterol
(**Check on this**)

Front 28

Which statement about diuretics is Incorrect?

Back 28

Diuretic increase blood volume

Front 29

All conditions are significant risk factors for development of CKD Except?

Back 29

Low dietary protein consumption

Front 30

ACE inhibitors have all indicated adverse effects except?

Back 30

Hypokalemia

Front 31

Angiotensin receptor antagonist have all indicated adverse effects Except?

Back 31

Hypokalemia

Front 32

Px on which of the following classes of agents or with indicated conditions do Not have increased risk of orthostatic hypotension?

Back 32

Statins

Front 33

Group II anti-arrythmic drugs?

Back 33

Block Beta-adrenergic receptors

Front 34

Which of the following statements concerning CKD is Not correct?

Back 34

General anesthetics but not local anesthetics are safe to use

Front 35

Which statements about Ca++ channel blockers is Not correct?

Back 35

Relax small veins but constrict larger veins

Front 36

Corticosteroids when used for routine tx of chronic asthma, are best administered by which route?

Back 36

Inhalation

Front 37

All are clinical symptoms of CHF Except?

Back 37

Increased urinary output

Front 38

Which is a Beta-adrenergic antagonist used in tx for CHF?

Back 38

Propranolol

Front 39

Which effect would be observed if binding of angiotensin II to the AT1 receptor were inhibited?

Back 39

Decreased vasoconstriction

Front 40

All are correct statements regarding isoproterenol Except?

Back 40

It binds with high affinity to alpha-adrenergic receptors

Isoproterenol is a Beta Agonist
It can be used in acute cases to speed the heart up

Front 41

Digoxin is used to tx CHF. Which statement about Digoxin is Correct?

Back 41

It directly inhibits Ca++ efflux by the muscle Na+ Ca++ antiporter

Front 42

Cholestramine (Questrin) is used as antihyperlipidemic agent because?

Back 42

Inhibits cholesterol uptake by intestine

Front 43

Of the following drugs, which would be drug of choice for tachycardia?

Back 43

Propanolol

Front 44

All of the cations are important in generating currents Except?

Back 44

Cl-

Front 45

Which of the following receptors is important for sensing short term changes in blood pressure?

Back 45

Baroreceptors

Front 46

Which tissue is responsible for pacemaker potentials that control contraction of the heart?

Back 46

Sinoatrial node

Front 47

Class II anti-arrhythmic have all properties Except?

Back 47

Are Na+ channel antagonists

Front 48

Leukotriene receptor antagonists and antihistamines are both used as tx for allergen-induced asthma. These are best used to?

Back 48

Prophylactically to prevent allergen mediated responses

Front 49

Pseudoephedrine and oxymetazoline are marketed as nasal decongestants. They are alpha-adrenergic agonists. Which effect is more likely after oral administration than intranasal administration?

Back 49

Increased blood pressure

Front 50

Minoxidil is used to treat?

Back 50

Hypertension
Minoxidil is an arteriole vasodilator