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18 Cards in this Set

  • Front
  • Back
What are the risks with Clomifene? (a fertility drug)
neural tube defects
What are the effects of fetal alcohol syndrome?
low forehead
sunken bridge of nose
retracted lips
cardiac defects
IURG
What are the physical signs of Warfarin syndrome?
hypoplastic saddle nose
broad short hands, short distal phalanges
opthalmic problems
bone problems
death in utero
When is warfarin contraindicated?
all trimesters of pregnancy
What should be used instead of warfarin?
heparin should be used- doesnt cross placenta
What causes Fetal hydantoin syndrome?
phenytoin
What are the symptoms of phenytoin use during pregnancy?
IUGR, MR
short nose, low nasal bridge
cleft lip/plate
cardiac defects
abnormal genitalia
absent finger/toe nails
What are the abnormalities of Diethylstilbestrol administration during pregnancy?
vaginal/cervical ridges

**adenocarcinoma of the vagina/cervix**
What does Hormonal steroid use in pregnancy cause?
VACTERL

vertebral, anal, cardiac, tracheal, rsophageal, renal, and limb defects
What does Isotretinoin do in pregnancy?
very teratogenic
-hydrocephaly, microcephaly, MR, ear/eye/palate problems, heart defects
What must women taking Isotretinoin do?
use two forms of birth control
What is pregnancy category A?
studies show no risk

levothyroxine/folic acid in here
What is pregnancy category B?
no risk in humans, despite a few adverse findings in animals
What is pregnancy category C?
no well control human studies, may show effects in animals.

use ONLY if needed
What is pregnancy category D?
has fetal risk

ONLY use if benefit outweighs risk for mom
What is pregnancy category X
RISK always outweights benefit.

contraindicated
What two drugs are contraindicated during 1st trimester?
metronidazole

tinidazole
What three drugs are contraindicated in 3rd trimester?
Aspirin/nsaids
bactrim
nitrofurantoin (causes hemolytic anemias)