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18 Cards in this Set
- Front
- Back
What are the risks with Clomifene? (a fertility drug)
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neural tube defects
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What are the effects of fetal alcohol syndrome?
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low forehead
sunken bridge of nose retracted lips cardiac defects IURG |
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What are the physical signs of Warfarin syndrome?
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hypoplastic saddle nose
broad short hands, short distal phalanges opthalmic problems bone problems death in utero |
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When is warfarin contraindicated?
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all trimesters of pregnancy
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What should be used instead of warfarin?
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heparin should be used- doesnt cross placenta
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What causes Fetal hydantoin syndrome?
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phenytoin
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What are the symptoms of phenytoin use during pregnancy?
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IUGR, MR
short nose, low nasal bridge cleft lip/plate cardiac defects abnormal genitalia absent finger/toe nails |
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What are the abnormalities of Diethylstilbestrol administration during pregnancy?
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vaginal/cervical ridges
**adenocarcinoma of the vagina/cervix** |
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What does Hormonal steroid use in pregnancy cause?
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VACTERL
vertebral, anal, cardiac, tracheal, rsophageal, renal, and limb defects |
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What does Isotretinoin do in pregnancy?
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very teratogenic
-hydrocephaly, microcephaly, MR, ear/eye/palate problems, heart defects |
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What must women taking Isotretinoin do?
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use two forms of birth control
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What is pregnancy category A?
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studies show no risk
levothyroxine/folic acid in here |
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What is pregnancy category B?
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no risk in humans, despite a few adverse findings in animals
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What is pregnancy category C?
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no well control human studies, may show effects in animals.
use ONLY if needed |
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What is pregnancy category D?
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has fetal risk
ONLY use if benefit outweighs risk for mom |
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What is pregnancy category X
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RISK always outweights benefit.
contraindicated |
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What two drugs are contraindicated during 1st trimester?
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metronidazole
tinidazole |
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What three drugs are contraindicated in 3rd trimester?
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Aspirin/nsaids
bactrim nitrofurantoin (causes hemolytic anemias) |