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30 Cards in this Set

  • Front
  • Back
What are contraindications for Levonorgestrel?
Contraindicated in active thrombophlebitis or thromboembolic disease, undiagnosed abnormal genital bleeding, known or suspected pregnancy, hepatic disease , benign or malignant liver tumors, known or suspected breast cancer.
Oral contraceptives are contraindicated in patients with
in known or suspected neoplasms do not use
Adverse effects or oral contraceptions
breast tenderness, weight gain, dizziness, and headaches
Adverse effects of Tamoxifen
priritus vulvae and dermatitis, pain or inflammation at the tumor site, cause uterine cancer, macular edema and retinopathy, nausea and vomiting, hot flashes
Adverse side effectss of Raloxifene
increased risk of deep-vein thrombosis (DVT), pulmonary embolism, retinal-vein thrombosis
A benefit of Toremifene over Tamoxifen is that it does not increase the risk of ______ cancer.
This drug is a nonsteroidal partial antagoist that induces ovulation presumaby by blocking hypothalamic estrogen receptors.
Clomiphene's MOA
Perogonal and Metodin are associated with what syndrome?
Ovarian hyperstimulation syndrome
Mifepriston is an ______
what class?
Give example of estrogens. Generic names
Diethylstilbestrol, estradiol, estriol,estrone, ethinyl estradiol, Mestranol
Young athletes who abuse andorgens ahould be made aware of the side effects of these drugs.... which are
Increased muscle mass, overly aggressive behavior, decreased spermatogenesis, stunted growth
A 70 year old woman is being treated with raloxifene for osteoporosis. There is an increased risk of her developing...
vein thrombosis
A 23 year old woman has failed to become pregnant after 2 years of unprotected intercourse. Which would be effective in treating infertility due to anovulatory cycles?
Treatments for osteoporosis include...
Dehydroepiandrosterone (DHEA), estradiol, tamoxifen, mestranol
Estrogen replacement therapy in menopausal women
is most effective if institured at the first signs of menopause.
A 66 year old man complained of decreased libido and difficulty maintaining an erection. He is currently taking tamsulosin for benign prostatic hyperplasia. He is concerned about the use of drugs to restore sexual function, particularly about the need to time therapy with anticipated sex. What is this patient's best option.
Tadalafil is indicated because it can be used comcomitantly with tamsulosin.
Which causes osteomalacia and bone pain when administered chronically?
58 yr old male has been effectively treated for Paget disease for approximately six months. He is now beginning to experience renewed bone pain and radiologic evidence of advancing disease. Which drug is most likely to have resulted in this failure of therapy?
Give examples of selective estrogen modulators?
Clomiphene, Raloxifene, Tamoxifen, and Toremifene
Hydroxyprogesterone, Medroxyprogeterone, Norehindrone, and Norgestrel are what class of drugs
Bicalutamide, Cyproterone acetate, Finasteride, Flutamide, Nilutamide are what class of drugs
Danazol, Fluoxymesterone, Nandralone, Stanozolol, and Testosterone cypionate are what class of drugs
What is the MOA of Progestins?
Increase in hepatic glycogen, decrease in Na reabsorption in the kidney due to competition with aldosterone at the mineralcorticoid receptor, increase in body temp, decrease in plasma amino acids, increase in excreation of urinary nitrogen
PMS, dysmenorrhea, and Dysfunctional uterine bleeding you can treat with what drug class?
Hypoventilation, endometriosis, supression of postpartum lactation, and carcinoma use what drug class?
Increased ratioof LDL to HDl is an adverse effect of what drug class?
This drug works by inhibiting ovulation during the follicular phase by blocking hypothlamic-pituitary progesterone receptors, which suppresses midcycle gonadotropin release.
Mifepristone MOA
Metastatic prostate cancer can be treated with ____ and ____
bicalutamide and nilutamide
Side effects of alpha 1 antagonists like terazosin, doxazosin, tamsulosin, and alfuzosin include
orthostatic hypotensin and dizziness
Finasteride is used in the treatment of benign prostatic hypertrophy. It takes how long to work?
6-12 months to improve symptoms