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84 Cards in this Set

  • Front
  • Back

Therapeutic Actions of Drugs

Palliative, Curative, Supportive, Substitutive, Chemotherapeutic, Restorative

Fundamental Rule of Safe Medication Administration

Never administer an unfamiliar medication

Also need to:

Be familiar with:


1. dosage ranges


2. expected therapeutic effects


3. side effects and potential adverse effects


4. interactions, drug drug, drug food


5. contraindications/precautions


6. special considerations

Misfeasance

Negligence, giving the wrong drug or dose that results in the clients death

Nonfeasance

Omission, omitting a drug dose that results in the clients death

Malfeasance

Giving the correct drug, but by the wrong route that results in the clients death

Nurse Practice Acts

Nurses can generally not prescribe or administer drugs, but some state laws allow it. Nurses should be aware...

Ethics

Nurses must follow ANA's code of ethics



Patients have the right to know?

about their drugs, the expected effects and any potential adverse reactions,

Patients have the right to do what?

refuse drugs

Beneficience

Doing something for the benefit of others

Nonmalfeasance

Doing no harm to patients

6 rights of drug administration

PDDRTD


Patient


Drug


Dose


Route


Time


Documentation

4 other rights of drug administration

right history and assessment


drug approach and right to refuse


right drug drug interaction and evaluation


right education and information

If you dont understand a medication order

Question it

Checking the patients identity

when alert and oriented


=ask name and date of birth




when altered mental staturs or reduced loss of conciousness


=check MAR against bracelet, compare name DOB medical record Number

Medication Error

is any preventable event that may cause or lead to inappropriate medication use or patient harm.

National Council for Medication Error Reporting and Prevention

Medication Error Index

NCC MERP Index

Category System

Category A

No Error, have the capacity to cause error

Category B

Error occured, but did not reach patient

Category C

Error occurred, did reach patient, did not cause harm

Category D

Error occurred, reached patient, patient is being monitored

Category E

Error occurred, temporary harm

Category F

Error occurred, temporary harm, prolonged hospitalization

Category G

Error occurred, permanent harm

Category H

Error occurred, life-sustaining intervention

Category I

Error occured, contributed to or resulted in death of patient

Harm

Impairment of the physical emotional or psychological function or structure of the body

Monitoring

Observe or record relevant physiological/psychological signs

Intervention

Change in therapy or active medical,surgical treatment

Life-sustaining interventions

CV and or respiratory support

types of medication errors

wrong: patient, drug, time, dose, dosaste form, dilutent, strength/concentration, infusion rate, technique, duration of treatment




omitted dose




deteriorated drug error

Medication Reconciliation

Keeping track, when going to other HCP




lists all medications in order to avoid/reduce duplications, omissions, dosing errors or drug interactions


-admissions


-transfer of care


-discharges

Risk Management

Examines risks and minimizes the number of medication errors


-nurses are required to contact wrong publishers

Pharmacology

Clinical Pharmacology


Pharmacokinetics, pharmacodynamics

Pharmacodiagnosis

the use of drugs in diagnosis

Pharmacotherapeutics

the use of drugs in therapeutics

Pharmacoeconomics

the use of economics to compare drug prices

Drug

Any substance that alters physiologic function can be positive or negative

Medication

drug admistered for therapeutic effects

all medications are drugs,

not all drugs are medications

local effects

act mainly at the site of application, dermatological products

systemic effects

absorbed into the bloodstream and circulated

Ideal drug properties

effectiveness, safe, selective, reversible, predictable, easy to administer, absense of itneractions, cheap, stable, simplified generic name

Adverse Effects

any noxious, unintended and undesired effect that occurs at normal drug doses


mild to life threatening


need to determine if relationship between drug and event

Black Box Warning

flags a serious warning so prescribers are aware


placed at the top of drug lable with black border around ti

Side Effects

secondary drug effect, that occurs at therapeutic doses


usually predictable and intensity is dose-dependent


may see immediately or months after drug initiated

Toxicity

ADR caused by excessive dosing


can also be organ-specific even if dose is therapeutic

allergic reaction

immune response


must have had prior sensitization to the medication


most common, penicillins, NSAIDS, and Sulfonamides

Idiosyncratic Effect, paradoxical

has the opposite effect to what is thought

Iatrogenic Disease

Essentially identical to a naturally occuring pathology

physical dependence

psychological need to be dependent on a drug

Carcinogenic Effect

causes cancer

Teratogenic Efffect

affects a developing embryo

Contraindication

a reason to withhold medical treatment

Precaution

treatment is given, but under monitoring

Where do drugs come from?

Plants, animals, inorganic compounds, synthetic, gnetically engineered

drug names

Chemical name, generic name, trade or brande name

drugs that share characteristics are grouped

2 basic, pharmagologic, therapeutic

many drugs can have multiple classifications

depends on clinical use of drug

prototype drug

agent to which other drugs in the class are compared

placebo drug

sugar pill , is not medical

Durham-Humphrey Amendment

1952 seperated drugs into two major classifications


-nonprescription


-prescription, legend

Sources of Drugd Information

People, textbooks, newsletters, reference books, internet

Pure food and Drug Act

1906

Sherley Amendent of

1912

Food, Drug and Cosmetic Act

Requires the manufacturer to submit a New Drug Application to the FDA prior to marketing

Kefauver-Harris Amendment

required advrse reactions and contraindication must be labeled and included in literature

Controlled Substance Act

Schedule 1-5


abuse potential

Childhood Vaccine act

1986

food and drug adminstration

1988 established as an agency of the us dept of health services

prescription drug user free act

1992

dietary supplemental health and education act

1994

FDA Modernization act

1997

Bioterrorism Act

2002

FDA Amendments ACT

critical path initiative

Investigational New Drug

fi drug appears promising

clinical phase trials

drug goes through 3 pahses with huamsn

pahse one

healthy volunteers, goals are to determine pharmokinetics and biologic effectsph

a se two

several hundred patietns with disease


appropriate doasage and therapeutic effectiveness

pahse three

large number of patients with disease


determine patient variability, interactions and ADRS

NDA

FDA examines to see if safe


CDER is oblicated to act on 90% of NDAs

postmarketing surveillance

after NDA review, see if harmful drug effects