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84 Cards in this Set
- Front
- Back
Therapeutic Actions of Drugs |
Palliative, Curative, Supportive, Substitutive, Chemotherapeutic, Restorative |
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Fundamental Rule of Safe Medication Administration |
Never administer an unfamiliar medication |
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Also need to: |
Be familiar with: 1. dosage ranges 2. expected therapeutic effects 3. side effects and potential adverse effects 4. interactions, drug drug, drug food 5. contraindications/precautions 6. special considerations |
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Misfeasance |
Negligence, giving the wrong drug or dose that results in the clients death |
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Nonfeasance |
Omission, omitting a drug dose that results in the clients death |
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Malfeasance |
Giving the correct drug, but by the wrong route that results in the clients death |
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Nurse Practice Acts |
Nurses can generally not prescribe or administer drugs, but some state laws allow it. Nurses should be aware... |
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Ethics |
Nurses must follow ANA's code of ethics |
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Patients have the right to know? |
about their drugs, the expected effects and any potential adverse reactions, |
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Patients have the right to do what? |
refuse drugs |
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Beneficience |
Doing something for the benefit of others |
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Nonmalfeasance |
Doing no harm to patients |
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6 rights of drug administration |
PDDRTD Patient Drug Dose Route Time Documentation |
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4 other rights of drug administration |
right history and assessment drug approach and right to refuse right drug drug interaction and evaluation right education and information |
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If you dont understand a medication order |
Question it |
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Checking the patients identity |
when alert and oriented =ask name and date of birth when altered mental staturs or reduced loss of conciousness =check MAR against bracelet, compare name DOB medical record Number |
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Medication Error |
is any preventable event that may cause or lead to inappropriate medication use or patient harm. |
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National Council for Medication Error Reporting and Prevention |
Medication Error Index |
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NCC MERP Index |
Category System |
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Category A |
No Error, have the capacity to cause error |
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Category B |
Error occured, but did not reach patient |
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Category C |
Error occurred, did reach patient, did not cause harm |
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Category D |
Error occurred, reached patient, patient is being monitored |
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Category E |
Error occurred, temporary harm |
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Category F |
Error occurred, temporary harm, prolonged hospitalization |
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Category G |
Error occurred, permanent harm |
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Category H |
Error occurred, life-sustaining intervention |
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Category I |
Error occured, contributed to or resulted in death of patient |
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Harm |
Impairment of the physical emotional or psychological function or structure of the body |
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Monitoring |
Observe or record relevant physiological/psychological signs |
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Intervention |
Change in therapy or active medical,surgical treatment |
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Life-sustaining interventions |
CV and or respiratory support |
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types of medication errors |
wrong: patient, drug, time, dose, dosaste form, dilutent, strength/concentration, infusion rate, technique, duration of treatment omitted dose deteriorated drug error |
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Medication Reconciliation |
Keeping track, when going to other HCP lists all medications in order to avoid/reduce duplications, omissions, dosing errors or drug interactions -admissions -transfer of care -discharges |
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Risk Management |
Examines risks and minimizes the number of medication errors -nurses are required to contact wrong publishers |
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Pharmacology |
Clinical Pharmacology Pharmacokinetics, pharmacodynamics |
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Pharmacodiagnosis |
the use of drugs in diagnosis |
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Pharmacotherapeutics |
the use of drugs in therapeutics |
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Pharmacoeconomics
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the use of economics to compare drug prices |
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Drug |
Any substance that alters physiologic function can be positive or negative |
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Medication |
drug admistered for therapeutic effects |
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all medications are drugs, |
not all drugs are medications |
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local effects |
act mainly at the site of application, dermatological products |
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systemic effects |
absorbed into the bloodstream and circulated |
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Ideal drug properties |
effectiveness, safe, selective, reversible, predictable, easy to administer, absense of itneractions, cheap, stable, simplified generic name |
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Adverse Effects |
any noxious, unintended and undesired effect that occurs at normal drug doses mild to life threatening need to determine if relationship between drug and event |
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Black Box Warning
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flags a serious warning so prescribers are aware placed at the top of drug lable with black border around ti |
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Side Effects |
secondary drug effect, that occurs at therapeutic doses usually predictable and intensity is dose-dependent may see immediately or months after drug initiated |
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Toxicity |
ADR caused by excessive dosing can also be organ-specific even if dose is therapeutic |
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allergic reaction |
immune response must have had prior sensitization to the medication most common, penicillins, NSAIDS, and Sulfonamides |
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Idiosyncratic Effect, paradoxical |
has the opposite effect to what is thought |
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Iatrogenic Disease |
Essentially identical to a naturally occuring pathology |
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physical dependence |
psychological need to be dependent on a drug |
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Carcinogenic Effect |
causes cancer |
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Teratogenic Efffect |
affects a developing embryo |
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Contraindication |
a reason to withhold medical treatment |
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Precaution |
treatment is given, but under monitoring |
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Where do drugs come from? |
Plants, animals, inorganic compounds, synthetic, gnetically engineered |
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drug names |
Chemical name, generic name, trade or brande name |
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drugs that share characteristics are grouped |
2 basic, pharmagologic, therapeutic |
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many drugs can have multiple classifications |
depends on clinical use of drug |
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prototype drug |
agent to which other drugs in the class are compared |
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placebo drug |
sugar pill , is not medical |
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Durham-Humphrey Amendment |
1952 seperated drugs into two major classifications -nonprescription -prescription, legend |
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Sources of Drugd Information |
People, textbooks, newsletters, reference books, internet |
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Pure food and Drug Act |
1906 |
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Sherley Amendent of |
1912 |
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Food, Drug and Cosmetic Act |
Requires the manufacturer to submit a New Drug Application to the FDA prior to marketing |
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Kefauver-Harris Amendment |
required advrse reactions and contraindication must be labeled and included in literature |
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Controlled Substance Act |
Schedule 1-5 abuse potential |
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Childhood Vaccine act |
1986 |
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food and drug adminstration |
1988 established as an agency of the us dept of health services |
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prescription drug user free act |
1992 |
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dietary supplemental health and education act |
1994 |
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FDA Modernization act |
1997 |
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Bioterrorism Act |
2002 |
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FDA Amendments ACT |
critical path initiative |
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Investigational New Drug |
fi drug appears promising |
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clinical phase trials |
drug goes through 3 pahses with huamsn |
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pahse one |
healthy volunteers, goals are to determine pharmokinetics and biologic effectsph |
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a se two
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several hundred patietns with disease appropriate doasage and therapeutic effectiveness |
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pahse three |
large number of patients with disease determine patient variability, interactions and ADRS |
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NDA |
FDA examines to see if safe CDER is oblicated to act on 90% of NDAs |
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postmarketing surveillance |
after NDA review, see if harmful drug effects |