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26 Cards in this Set

  • Front
  • Back
Adverse effects
undesired effects of a drug that may be harmful and require reduction in dose or discontinuation of the preparation.
a drug that binds to a receptor to produce an effect.
a drug that binds to a specific receptor to block the action of a chemical body substance or agonist drug from binding to the receptor.
conditions, diseases, situations, or patients where use of a drug is not indicated
exact amount of a drug that is administered to produce a specific effect
dose response curve
condition or disease for which a drug is given
mechanism of action
explanation of how a drug produces its intended therapeautic effect
study of the process of drug absorption, disruption, metabolism, and excretion
the power of strength of a drug at a specified concentration
receptor site
the specific location on the cell membrane where a drug binds to form a drug-receptor complex
side effects
effect of a drug other than the therapeutic effect.
site of action
place in the body where a drug produces a desired therapeutic effect
therapeutic effect
the desired medicinal effect of a drug
time-response curve
mathematical curve that plots the effect of a particular drug dosage over time
toxic effects
undesired effects that produce serious toxicity that usually lead to discontinuation of the drug and alternative therapy
Chemical name
specific chemical description of a drug
generic name
non proprietary name, often a shortened version of the chemical name
trade name
proprietary name, name assigned by the pharmaceutical company marketing a drug
effective dose 50 - does that will produce half of the maximal drug response, determined from a dose -response curve
lethal dose 50 - dose of a drug that will kill 50% of test animals. it is determined from a lethal dose-response curve.
therapeutic index - ratio of the LD50 to the ED50, used to predict drug safety
percentage of a drug dose that is absorbed
drug absorption
entrance of a drug into the bloodstream from its site of administration
drug distribution
passage of a drug from the blood to the tissues of the body
drug metabolism
biotransformation - the chemical alteration of a drug in the body. often occurs prior to excretion of a drug.
drug exrcretion
process by whice substances, including drugs, are removed from the body.