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42 Cards in this Set

  • Front
  • Back
aspirin
non opiod analgesic
salicylate
inhibits COX
anti pyresis by hypothalamic inhibition
inhibits platelet aggregation
mild to moderate pain
salicylic acid
aka aspirin
acetaminophen
non opioid analgesic
inhibits COX
anti pyresis by hypothalamic inhibition
very weak anti-inflammatory
ibuprofen
non opioid analgesic
inhibits COX
anti pyresis by hypothalamic inhibition
very weak anti-inflammatory
danger of hemolytic anemia & methemoglobinemia
sulindac
NSAI
inhibits COX
analgesic, anti-inflamm, antipyretic
mild to moderate pain
morphine
derived from opium poppy
naturally-occurring narcotic
mu receptor agonist
analgesia, euphoria, respiratory depression, physical dependence
codeine
derived from opium poppy
naturally-occurring narcotic
mu receptor agonist
analgesia, euphoria, respiratory depression, physical dependence
methadone
aliphatic class of synthetic narcotics
acts on mu receptors
naproxen
NSAID
proprionic acid derivative
analgesic, antiinflammatory, antipyretic
meclofenamate sodium
inhibits prostaglandin synthesis
joint and muscle pain
hydroxychloroquine
antimarial agent with some antiarthritic effects
lysosomal membrane stabilizer
methotrexate
antiarthritic, antifolate agent
inhibits adenosine degradation, inhibiting cytokine production
teratogenic
pentazocine
benzomorphan class of synthetic narcotics
partial agonist-antagonist
celecoxib
NSAID used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with FAP
colchicine
relieves acute gouty inflammatory attacks, prophylactic also
inhibits granulocyte migration
GI, renal, and CV problems
probenecid
a uricosuric drug that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia.
allopurinol
anti-gout
inhibits xanthine oxidase at both purine sythesis steps
competitive (low dose) and noncompetitive (high dose) inhibition
hypersensitivity, blood dycrasias
infliximab
monoclonal antibody against TNFα used to treat autoimmune diseases
nalbuphine
synthetic narcotic
equipotent with morphine
parenteral use
lsee psychotomimetic effects than others
CV effects similar to morphine, can use in MI
fentanyl
piperidine class of sythetic narcotic analgesics
mu receptor agonist
diphenoxylate
opioid agonist used for the treatment of diarrhea that acts by slowing intestinal contractions and peristalsis
Benzocaine
local anesthetic topical only
minimal absorption d/t low aqueous solubility
Cocaine
local anesthetic
topical application, esp mucus membranes
high potential for toxicity in CVS or CNS
sympathomimetic
Procaine
first synthetic local anesthetic
relatively slow onset and short duration
Lidocaine
local anesthetic
rapid onset and intermediate duration
Bupivacaine
local anesthetic
more potent, toxic, and longer-acting than lidocaine
slower onset
Thiopental
sedative hypnotic
ultra-short acting barbituate
rapid induction of anesthesia or short procedures w/ little pain
Midazolam
benzodiazepine
pre or intraoperative sedation and amnesia
reversible w/ flumazenil
Fentanyl
short acting opioid, adjunct
rapid onset
profound analgesia w/ incomplete amnesia and no skeletal muscle relaxation
Ketamine
phencyclidine derivative
trance-like dissociative state
induction, sedation, and analgesia
profound analgesia & amnesia but little/no muscle relaxation
minimal respiratory depression
CV stimulation
Etomidate
induction and maintenance of anesthesia; hypnotic
children or patients w/ limited cardiac reserve
minimal CV or resp depression
Propofol
sedation, induction, and maintenance of anesthesia
hypnotic w/ no analgesic properties
antiemetic
fast recovery vs thiopental
CV & resp depression
Nitrous Oxide
inhaled anesthetic
low potency and low solubility
rapid onset and recovery
good analgesic but minimal relaxation
Halogenated Agents
inhaled anesthetic
high potency and low to mod solubility
slight to mod analgesia
variable relxation
dose-dep resp and CV depression
inc intracranial pressure
acetazolamide
carbonic anhydrase inhibitor
furosemide
loop diuretic
hydrochlorothiazide
thiazide diuretic
indapamide
thiazide-like diuretic
spironolactone
Aldosterone receptor antagonist
K+ sparing diuretic
eplerenone
Aldosterone receptor antagonist
K+ sparing diuretic
amiloride
Na+ channel blocker
K+ sparing diuretic
Mannitol
osmotic diuretic