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15 Cards in this Set

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  • Back
Name the organs innervated by the alpha-1 receptors.
1. Radial muscle, iris
2. Canal of SChlemm
3. Arterioles
4. Bronchial glands
5. Proximal tubules
6. Trigone
7. Urethra
8. Vas deferens
9. Pilomotor muscle
10. Salivary glands
Name the organs innervated by alpha 2 receptors.
1. Canal of Schlemm
2. Arterioles
3. Stomach and intestine - motility and tone, secretion
4. Platelets
5. Islet cells (insulin)
Name the organs innervated by alpha receptors.
1. Smooth muscle of the eyelid
2. Pregnant uterus
3. Pancreatic acinar cells
Name the organs innervated by Beta 1 receptors.
1. Heart
2. JG cells
3. Adipocytes
Name the organs innervated by Beta 2 receptors.
1. Arterioles
2. Bronchial muscle
3. Pregnant and nonpregnant uterus
4. Gallbladder and ducts.
5. Skeletal muscle
6. Liver
Name the organs innervated by beta receptors?
Islet cells (glucagon)
Name the innervation for sweat glands.
Muscarinic (adrenergic)
Name organs that are innervated by parasympathetics only.
Sphincter muscle, iris
Ciliary m
Esophagus
Acid secretion in stomach
Detrusor muscle
Penis
Urethral and bulbourethral gland
Clitoris and area around introitus
Bartholin's gland
Lacrimal gland
Nasopharyngeal gland.
What happens with older anti-histamine?
They activate histamine receptors and also muscarinic cholinergic receptors.

Therefore the side effects of sleepiness, dry nose, dry mouth.
Describe the parasympathetic innervation in the penis.
NO causes the relaxation of the arterioles therefore allowing the pooling of blood the penis.
What does the NE released from the sympathetic fibers do?
1. Bind alpha 2 receptors on vagal cardiac fiber (inhibitory)

2. Bind Beta 1 receptors on the SA node (excitatory)

3. Bind alpha 2 receptors on itself (autoreceptor) to decrease the release of more NE.
What does the Ach released from the parasympathetic fibers do?
1. bind to M2 receptors on sym fibers (inhibitory)

2. bind to M2 receptors on the SA node (inhibitory)

3. bind to M2 receptors on itself (autoregulation)
What is the MOA of alpha 2 receptors on effector organs?
Increase inhibition of AC therefore decrease cAMP
What is the MOA of alpha 2 receptors on autoreceptors?
Increase K conductance
What is the MOA of alpha 2 receptors on SA node, sphincter muscle of iris and GI tract?
Increase K conductance.