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5 Cards in this Set

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  • Back
inhibitors of cholesterol synthesis used for hypercholesterolemia, familial hypercholesterolemia, coronary atherosclerosis, prophylaxis for coronary atherosclerosis

side effects: myopathy, rhabdomyolysis,, dermatomyositis, abdominal pain, constipation, diarrhea, nausea, headache

contraindications: active liver disease, pregnancy/lactation
lovastatin, pravastatin, simvastatin, fluvastatin, atorvastatin, rosuvastatin
inhibitors of bile acid absorption used for hypercholesterolemia, pruritis (Cht only)

side effects: increase in triglyceride levels, bloating, dyspepsia, flatulence, bleeding diathesis, secondary to Vit K deficiency

contraindications: complete biliary obstruction, hyperlipidemia types III, IV, or V
cholestyramine, colesevelam, colestipol
inhibitor of cholesterol absorption used for primary hypercholesterolemia, familial hypercholesterolemia, sitosterolemia

side effects: elevated liver function tests, myopathy, dyspepsia, arthralgia, myalgia, headache

contraindications: active liver disease, persistently elevated liver function tests when coadministered with statin
drugs used for isolated hypertriglyceridemia, hypertriglyceridemia with low HDL, type III dysbetalipoproteinemia

side effects: elevated liver function tests, myopathy when coadministered with a statin, arrhythmias, dyspepsia, myalgia, gallstone, xerostomia

contraindications: concomitant gemfibrozil adn cerivastatin, preexisting gall bladder disease, hepatic dysfunction, severe renal impairment
Fibrates: gemfibrozil and fenofibrate
drug used for isolated low HDL, low HDL with mildly elevated LDL or triglycerides, familial combined hyperlipidemia

side effects: hepatotoxicity, GI bleeding, flushing, pruritis, hyperuricemia adn gout, impared insulin sensitivity, myopathy

contraindications: active liver disease, active peptic ulcer, arterial bleeding