Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
What effects do NSAIDS have on the body?
|
analgesia, anti-inflammation, anti-coagulant, anti-pyretic (reduces fever)
|
|
|
What drug blocks the leukotriene receptor?
|
Montelukast, zaphirleukast
|
|
|
When aspirin is used, its side effects are most related to what physiologically?
|
COX-1 inhibition (effects:gastric acid production, reanal activity, platelet activity)
|
|
|
What are side effects of aspirin?
|
GI upset, tinnitis, vertigo, kidney & liver damage), Reye's syndrome
|
|
|
What is acetaminophen most effective at reducing?
|
pain & fever. Not anti-inflammatory.
|
|
|
What differs between corticosteroids and NSAIDS?
|
Corticosteroids are beter at inhibiting leukotrienes & more effacious
|
|
|
Which DMARD has the best therapy to toxcity ratio?
|
Methotrexate
|
|
|
What is Leflunomide and what are it's side effects?
|
DMARD that works within 1st month. SE: GI, allergic, hair loss, hepatotoxic
|
|
|
Where would you find nicotinic acetylcholine receptors?
|
neurons, skeletal muscle
|
|
|
What drugs inhibit acetylcholine esterase & are reversible?
|
Neostigmine, physostigmine, edrophonium.
|
|
|
What drugs inhibit acetylcholine esterase and are irreversible?
|
Insecticides, nerve gases.
|
|
|
What are cholinergics used to treat?
|
Glaucoma, Tachycardia, atropine intoxication
|
|
|
SLUD relates to poisoning by cholinergics. What does it stand for?
|
Salivation, lacrimation, urination, defecation
|
|
|
Name the different classes of direct acting cholinergic stimulants and drugs?
|
CHOLINE ESTERS: Bethanechol. Methacholine
ALKALOIDS: Muscarine, Nicotine, Pilocarpine |
|
|
Describe the sympathetic nervous system pre to post ratio, & post ganglionic release?
|
1:20 ratio. 20 dendrites. Norepinephrine to muscle & glands, Ach to sweat glands. EPI and NE from adrenal cells 4:1 ratio.
|
