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10 Cards in this Set
- Front
- Back
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the pluriponent hematopoietic stem cell gives rise to
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lymphoid stem cell and trilineage myeloid stem cells
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lymphoid stem cells give rise to
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b cells and t cells
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Trilineage myeloid stem cells give rise to
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neutrophils
eosinophils basophils mast cells monocytes which become macrophages |
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In the blood trilineage myeloid stem cells give rise to
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megakaryocytes which become platelets
erythroblasts which become erythrocytes |
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Describe the innate immune system
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First response
Bacterial and parasitic infections Granulocytes Mast cells Antigen presenting cells Macrophages Dendritic cells |
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antigen presenting cells MHC I are found on and have a?
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nucleated cells and have a CD 8 T-cell binding site
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Antigen presenting cells MHC II are found on and have a ?
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non-nucleated cells and have a CD-4 T-cell binding site
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Describe the adaptive immune system
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Specific response Generated response
MHC protein - B or T cell interaction Native vs. foreign cell recognition Infected cell/agent vs. uninfected cell Humoral immunity Cellular immunity TC cells - CD8 - mediates cell death TH cells - CD4 - regulates cytokines, B-cells |
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Cytotoxic T-cells bind____________ and lead to _____________
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MHC Class I- CD-8
mediated cell death |
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Helper T Cells bind____________ and lead to _____________
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MHC class II CD-4
regulates cytokines, B-cells |
