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15 Cards in this Set

  • Front
  • Back
Name five drugs that cause thyroid disorders.
Amiodarone (can cause hypo- and hyper-)
Salicylates (doses >2grams/day --> hypo-)
Anticonvulsants (lower total T4)
Lithium (hypo- and thyrotoxicosis)
Interferon-alpha (mostly hypo-)
Should levothyroxine be taken on a full or empty stomach?
empty stomach
What are two important drug interactions with levothyroxine?
Warfarin - patients need more warfarin
Digoxin - lower doses required
Are different levothyroxine products interchangable?
No.
What is the dosing for levothyroxine?
1.6-1.7 mcg/kg/day (100-125 mcg)
After initiating therapy with levothyroxine, when should you recheck the patients TSH levels?
in 6-8 weeks
In what increments should you adjust levothyroxine?
12.5-25 mcg/day
What happens if you suppress TSH to below normal?
Osteoporosis, cardiac toxicity
In a pregnant patient, how often should you monitor their FT4 and TSH levels?
Monthly during the 1st trimester
True or False:
In a patient with hypothyroidism, concurrent hyperlipidemia gets worse with thyroid treatment.
False: hyperlipidemia often normalizes with treatment.
In a patient who is hyperthyroid, do they need more or less warfarin?
Less because the effects are exaggerated.
In a patient who is hyperthyroid, do they need more or less digoxin?
More because higher amounts are required while thyrotoxic.
What drug is preferred for thyroid storm and in pregnancy?
PTU
What is the preferred drug for hyperthyroidism?
Methimazole
How long do you treat hyperthyroidism?
1-2 years