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18 Cards in this Set

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Classes of drugs to treat HTN: (5)

1) ACE Inhibitors


2) Beta-Blockers


3) Loop Diuretics


4) Vasodilators


5) Calcium Channel Blockers


6) ARBs (Angiotension II - Receptor - Blockers)

ACE Inhibitors

"-pril"


- block conversion of Angiotension I --> Angiotension 2


= reduce aldosterone


= reduce sodium and water retention


*increase potassium*

Lisinopril

ACE Inhibitor


- treats hypertension

Side effects: ACE Inhibitor

- cough***


- dizziness, headache, hypotension


- hyperkalimeia**


- reduce sodium and water + increase potassium


- angioedema

Enalapril

ACE Inhibitor


- treats hypertension w/ longer half life*

Hydralizine

direct-acting Vasodilator


- treats HTN

How do calcium channel blockers reduce HTN?

- decrease cardiac contractility


- vasodilate

What would you use for patient with diabetes to treat HTN?

ACE inhibitor -or- ARBs

What would you use for patient with heart failure to treat HTN?

Beta-Blocker

Potassium-sparing diuretic

Spironolactone (Aldactone)

Nefedipine

Calcium channel blocker

Spironolactone (Aldactone)

- Aldosterone antagonist


- potassium sparing diuretic



Which drug class protects the kidney?

ACE Inhibitors

Contraindications: ACE Inhibitors

- diabetes*


- renal impairment


- hemodialysis*


- when used w/ potassium sparing diuretics

"-sartan"

ARBs


- increase potassium secretion


- no cough*

Which Calcium Channel Blocking drugs decrease both BP and cardiac contractility?

- Diltiazem


- Verapamil

Which Calcium Channel Blocking drugs decrease only BP?

- Nifedipine


- Amlodipine

Adverse effects: Hydralazine

- reflex tachycardia*


- hypotension


- lupus-like symptoms*


- nausea + diarrhea