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18 Cards in this Set
- Front
- Back
Classes of drugs to treat HTN: (5) |
1) ACE Inhibitors 2) Beta-Blockers 3) Loop Diuretics 4) Vasodilators 5) Calcium Channel Blockers 6) ARBs (Angiotension II - Receptor - Blockers) |
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ACE Inhibitors |
"-pril" - block conversion of Angiotension I --> Angiotension 2 = reduce aldosterone = reduce sodium and water retention *increase potassium* |
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Lisinopril |
ACE Inhibitor - treats hypertension |
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Side effects: ACE Inhibitor |
- cough*** - dizziness, headache, hypotension - hyperkalimeia** - reduce sodium and water + increase potassium - angioedema |
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Enalapril |
ACE Inhibitor - treats hypertension w/ longer half life* |
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Hydralizine |
direct-acting Vasodilator - treats HTN |
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How do calcium channel blockers reduce HTN? |
- decrease cardiac contractility - vasodilate |
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What would you use for patient with diabetes to treat HTN? |
ACE inhibitor -or- ARBs |
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What would you use for patient with heart failure to treat HTN? |
Beta-Blocker |
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Potassium-sparing diuretic |
Spironolactone (Aldactone) |
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Nefedipine |
Calcium channel blocker |
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Spironolactone (Aldactone) |
- Aldosterone antagonist - potassium sparing diuretic |
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Which drug class protects the kidney? |
ACE Inhibitors |
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Contraindications: ACE Inhibitors |
- diabetes* - renal impairment - hemodialysis* - when used w/ potassium sparing diuretics |
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"-sartan" |
ARBs - increase potassium secretion - no cough* |
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Which Calcium Channel Blocking drugs decrease both BP and cardiac contractility? |
- Diltiazem - Verapamil |
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Which Calcium Channel Blocking drugs decrease only BP? |
- Nifedipine - Amlodipine |
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Adverse effects: Hydralazine |
- reflex tachycardia* - hypotension - lupus-like symptoms* - nausea + diarrhea |