Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
Estrogen Benefit |
control menopause symptoms block bone reabsorption, suppress osteoclast activity, & prevent osteoporosis after menopause Decrease LDL and increase HDL |
|
|
Estrogen ADR |
endometrial hyperplasia & carcinoma, increase risk of endometrial cancer increased risk of breast cancer with prolonged use (>4 yrs) Increased clotting factors *Always use with progestin |
|
|
Progestin Benefit |
Antagonize ADRs of estrogen use if intact uterus (hysterectomy) |
|
|
Progestin ADR |
Breakthrough bleeding spotting amenorrhea |
|
|
HRT patient education |
breast physical examination yearly mammogram yearly if >50 yrs, baseline at 40 yrs take with food reports ADRs to physician |
|
|
Combination oral contraceptive |
Ethinyl estradiol + levonorgestrel OR norethindrone |
|
|
COC Efficacy |
99%, 95-97% in real world (monophasic, biphasic, triphasic & extended) |
|
|
COC MOA |
1. Inhibit ovulation 2. Cervical mucous less favorable to sperm migration 3. Less favorable to implantation |
|
|
COC ADR |
Venous thromboembolism (DVT & PE) arterial thrombosis (MI & stroke) hypertension breakthrough bleeding/spotting amenorrhea nausea breast tenderness headache HTN migraine depression weight gain fatigue |
|
|
COC contradictions |
breast cancer past history of blood clot, CAD, angina, 3 wks postpartum pregnancy |
|
|
COC warnings |
Smoking surgical procedure >35 yrs **Decreases breast milk production |
|
|
Progestin only contraceptive |
Mini Pill |
|
|
Mini Pill ADR/ Contradictions/Warnings |
Same as COC |
|
|
Mini Pill MOA |
1. Sperm migration 2. Prevent implantation 3. Inhibit ovulation |
|
|
Mini Pill Efficacy |
22 hrs after dosing loses efficacy Take same time each day! >3 hrs after dosing is missed dose
|
|
|
Plan B
|
Levonorgestrel (progestin only)
|
|
|
Plan B MOA |
Inhibit ovulation, prevent implantation |
|
|
Plan B ADR |
N/V headache breast tenderness
|
|
|
Plan B Efficacy |
Take within 72 hrs (otc if >18) |
