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108 Cards in this Set
- Front
- Back
Amitriptyline
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Antidepressants, Pain
Class: Tricyclics Mechanism: Block reuptake NE which leads to A2 downreg., also works on serotonin receptors Side Effects: sedation, anticholinergic (dry eyes, mouth, constipation, blurred vision) OH, seizures |
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Phenelzine
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Antidepressants
Class: MAO Inhibitors Mechanism: Block degradation of NE in axon terminal which leads to more NE available to release Side Effects: restlesness, agitation, anticholinergic Notes: Used for PARKINSONS Nasty drug Many Contrainds: don’t take w cold meds (CV crisis) or cheese, choc, wine (have tyromine) |
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Paroxetine (Paxil)
Zoloft Prozac |
Antidepressant
Class: SSRI – Selective serotonin reuptake inhibit. Mechanism: Block reuptake Serotonin Side Effects: same as tricyclics, but less severe slight resting tremor Notes: Can be used for OCD and anxiety as well. May be given w sedative b/c tremors. |
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Wellbutrin (Bupropion)
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Antidepressants
Class: others Mechanism: Acts like dopamine Side effects: tremor, seizure, psychosis |
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Xanax
Clonazapam Diazepam (Valium) Lorazepam (Ativan |
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)
Class: Benzodiazepines Mechanism: GABA opens channel to kept open longer to more hyperpolarization Side Effects: Sedation, muscle weakness, dependence Notes: See pt at valley (also used for anti-seizure, anti-anxiety, sedation, spasm, spasticity, and anesthetic) |
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Buspirone (Buspar)
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Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)
Class: Azapirones Mechanism: Serotonin Agonist Side Effects: less sedation, tolerance, dependance Notes: |
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Cymbalta
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Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)
Class: SSRI AND Tricyclic Mechanism: Blocks reuptake NE and Seratonin Side effects: Notes: |
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Antianxiety drugs:
Class: Beta Antagonist |
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)
mechanism: Block B1 receptors, Works more in PNS side effects: Decrease HR notes: When need to reduce anxiety is certain situations (performer) |
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Antianxiety drugs:
Class: Alpha 2 Agonist |
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)
Mechanism: Works more in PNS side effects: Decrease all SNS effects notes: When need to reduce anxiety is certain situations (performer) |
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Lithium
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Treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression
mechanism: mechanism unclear, may mimic Na side effects: Tremor (fine in low dose, course in high) Muscle weakness, respiratory depression Confusion, lack of concentration, nystagmus |
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Resperidone (Risperdal)
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treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression
class: Selective Dopamine Antagonists mechanism: Inhibit DA receptors in limbic system (not ones in basal ganglia) side effects: Progression: anticholinergic (less) Parkinsonism (less) Tardive dyskenesia (less) Sedation (less) notes: increase dose leads to increase risk of side effects |
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Carbamazepine (Tegretol)
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treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression
class: Antiseizure Meds mechanism: blocks Na+ channels to prevent AP |
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Gabapentin (Neurontin)
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treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression
mechanism: GABA release side effects: Sedation, Fatigue, Ataxia notes: Not really a GABA agonist |
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Dopamine Antagonists:
Halodol |
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.
class: High Potency mechanism: Block ALL DA receptors side effects: Mostly motor dysfunction. strongly extrapyramidal , some anticholinergic, sedation, orthostatic hypotension notes: Extrapyramidal = dystonia, akathesia (pacing?), parkinson symptoms, dyskinesias 80’s |
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Dopamine Antagonists:
Chlorpromazine (Thorazine) |
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.
class: Low Potency mechanism: Non-selective side effects: strongly anticholinergic, some extrapyramidal, sedation, orthostatic hypotension notes: 50’s |
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Dopamine Antagonists:
Clozapine (Clozaril), Resperidone (Risperdal), |
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.
class: Atypical Agents mechanism: Selective for DA receptors in limbic system side effects: less frequency and intensity of above notes: Side effects are dose dependent. |
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Sinemet
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Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)
Side effects: arrhythmias, GI dysfunction (peripheral) dyskinesia, psychotic like behavior (central) notes: combination of l-dopa and carbidopa |
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class: dopamine agonists
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Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)
side effects: too many peripheral side effects notes: selective drugs offer fewer side effects: ( Mirapex, ReQuip) |
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Atropine
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Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)
class: Anticholinergic notes: Help reduce resting tremor |
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class: MAO inhibitor
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Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)
mechanism: prevents the break down NE |
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Symmetrel
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Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)
class: Amantadine mechanism: Antiviral agent |
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Triazolam (Halcion)
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Sedatives (relax) and Hypnotics (sleep):
class: Benzodiazepines mechanism: inhibit neurons in reticular formation bind all 3 subunits of GABA A (Alpha 1- sedation Alpha 2 & 3- antianxiety. dependance ) side effects: drowsy, muscle weakness, “hangover” notes: |
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Barbiturates - Phenobarbital
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Sedatives (relax) and Hypnotics (sleep):
class: Non-Benzodiazepines mechanism: bind GABA A (reticular formation, limbic) may increase glycine at high doses, depress neurons in higher brain centers (anesthesia) side effects: “hangover”, muscle weakness, Small Therapeutic Index leads to death if exceed notes: tolerance, dependency |
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Zolpidem (Ambien)
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Sedatives (relax) and Hypnotics (sleep):
class: mechanism: Appear to bind only the Alpha 1 subunit of GABA A side effects: Fewer side effects notes: Newer Dependency not a problem |
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Antihistamines - Benadryl
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Sedatives (relax) and Hypnotics (sleep):
class: mechanism: First Generation drugs enter CNS and decrease Histamine release from nerve terminals side effects: notes: Become desensitized after 3 days |
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FOR SPASMS:
Diazepam (Valium) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: Benzodiazepines mechanism: GABA mechanism side effects: sedation, generalized weakness notes: |
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FOR SPASMS:
Skelaxin, Skelex (don’t need to know) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: Polysynaptic Inhibitors mechanism: side effects: notes: several interneurons involved in reflex at spinal cord |
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FOR SPASTICITY:
Baclofen (oral) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: Binds GABA B- inhibition of alpha motor neurons in spinal cord--keep K+ channels open side effects: muscle weakness, fatigue, drowsiness, in CVA and elderly to confusion and hallucinations notes: |
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FOR SPASTICITY:
Baclofen (pump) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: Intrathecal to delivery to subarachnoid space side effects: less systemic effects, fewer hallucinations in CVA, elderly notes: For severe spasticity lower doses |
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FOR SPASTICITY:
Diazepam (Valium) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: side effects: notes: USED FOR BOTH |
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FOR SPASTICITY:
Gabapentin (Neurontin) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: inhibits alpha motor neuron mechansim unclear- not same receptors as GABA side effects: sedation, fatigue, dizziness, ataxia notes: |
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FOR SPASTICITY:
Tizanidine (Zanaflex) |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: Alpha 2 agonist to Inhibits interneurons that are stimulatory to alpha motor neurons, block NE release side effects: sedation, dizziness, dry mouth less generalized weakness than other relaxants less cardiac effects than clonidine notes: |
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FOR SPASTICITY:
Botulinum Toxin |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: Destroys SNARE proteins at NMJ therefore vesicles can’t release NT side effects: Respiratory depression notes: Direct Acting, Injection into site ~ 3 month intervals, also used for hyperactive bladder with CVA, better fit of orthotics, cosmetic |
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FOR SPASTICITY:
Dantrolene Sodium |
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction
class: mechanism: Blocks release of Ca++ from SR to no contraction side effects: muscle weakness, hepatotoxicity , drowsiness, dizziness notes: Direct Acting, also used for Malignant Hyperthermia (increased Ca release to very strong contractions leads to temp rise) |
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Phenobarbital
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Seizure Meds:
class: Barbiturates mechanism: Increase GABA effects side effects: (tolerance, dependence) Sedation, weakness, hyperactivity in some notes: |
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Clonazepam (klonopin)
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Seizure Meds:
class: Benzodiazepines mechanism: Increase GABA effects side effects: (tolerance, dependence) Sedation, weakness, notes: |
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class: Hydantoins
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Seizure Meds:
class: mechanism: slow recovery of Na+ channels in rapidly firing neurons side effects: Sedation, dizziness, hirsutism, headache notes: often first choice for partial, tonic-clonic |
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Carbamazepine (Tegretol)
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Seizure Meds:
class: Iminostilbenes mechanism: slow recovery of Na+ channels in rapidly firing neurons side effects: Dizziness, drowsiness, water retention (ADH), CHF, arrhythmia notes: Treats all but absence seizure |
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class: Succinimides-
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Seizure Meds:
class: mechanism: slow recovery of Na+ channels in rapidly firing neurons side effects: Sedation, dizziness, hirsutism, headache notes: often first choice for partial, tonic-clonic |
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class: Valproic Acid
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Seizure Meds:
mechanism: Increases GABA at high dose Still works at low dose withouut GABA but ????? side effects: GI distress, hirsutism,wt gain or loss notes: Treats absence or as secondary in tonic/clonic |
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Felbatol
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Seizure Meds:
class: Felbamate- mechanism: blocks actions of glutamate side effects: NOT BETTER, BUT FEWER SIDE EFFECTS? notes: Second Generation Drugs |
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Neurontin
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Seizure Meds:
class: Gabapentin mechanism: GABA agonist? Increases GABA release? side effects: NOT BETTER, BUT FEWER SIDE EFFECTS? notes: Second Generation Drugs |
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Lamictal
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Seizure Meds:
class: Lamotrigine mechanism: stabilizes Na+ channels side effects: NOT BETTER, BUT FEWER SIDE EFFECTS? notes: Second Generation Drugs |
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Topomax
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Seizure Meds:
class: Topirimate mechanism: inhibits Na+. Increases GABA, blocks glutatmate action side effects: NOT BETTER, BUT FEWER SIDE EFFECTS? notes: Second Generation Drugs |
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Benzodiazepines
Phenytoin phenobarbital |
Status Epilepticus Drugs: Series of seizures without recovery period
Caused by Sudden withdrawal of anti-seizure medication, cerebral infarct, Alcohol withdrawal notes: IV |
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Diazepam (Valium), Lorazepem (Ativan)
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General Anesthetics- IV: rapid onset, less control, CNS depressants
class: Benodiazepines- mechanism: side effects: notes: |
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Thiopental (truth serum)
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General Anesthetics- IV: rapid onset, less control, CNS depressants
class: Barbiturates mechanism: side effects: notes: |
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Ketalar
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General Anesthetics- IV: rapid onset, less control, CNS depressants
class: Ketamine mechanism: dissociative anesthesia, inhibits glutamate side effects: notes: for short procedures |
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Fentanyl+Droperidol
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General Anesthetics- IV: rapid onset, less control, CNS depressants
class: Opiate + Antipsych mechanism: dissociative without loss of consciousness side effects: notes: |
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Propofol (Diprivan)
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General Anesthetics- IV: rapid onset, less control, CNS depressants
class: Short acting hypnotic mechanism: GABA mechanism side effects: notes: lots of this in trauma centers |
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Halothane
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General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV! class: Halogenated volatile liquids- mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia) Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli) Interfere with Na+ channel? GABA binding, ACH inhibition? side effects: Confusion, muscle weakness, Lethargy, respiratory depression notes: |
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desflurane
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General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV! class: Halogenated volatile liquids- mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia) Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli) Interfere with Na+ channel? GABA binding, ACH inhibition? side effects: Confusion, muscle weakness, Lethargy, respiratory depression notes: Newer drugs- faster onset, recovery |
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Nitrous oxide
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General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV! class: Gas anesthetic mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia) Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli) Interfere with Na+ channel? GABA binding, ACH inhibition? side effects: Confusion, muscle weakness, Lethargy, respiratory depression notes: shorter procedures |
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Pancuronium, Tubocurrarine
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: Nondepolarizing agents mechanism: Block Nicotinic receptors (competitive antagonists) side effects: Both lead to muscle paralysis, increase histamine release and affect lungs notes: |
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Succinylcholine (Anectine)
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: Depolarizing agents mechanism: Bind N receptor and depolarize muscle, Drug not readily inactivated by cholinesterase side effects: Both lead to muscle paralysis, increase histamine release and affect lungs notes: |
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opiates, benzodiazepins, barbiturates
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: Sedatives mechanism: side effects: notes:depends on type of anesthesia |
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Antihistamines
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: mechanism: side effects: notes: sedate, reduce vomiting |
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Antacids
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: mechanism: side effects: notes: reduce risk of lung injury from aspiration |
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Anti-inflammatory steroids-
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General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS class: mechanism: side effects: notes: help prevent vomiting, pain |
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class: -Caines
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Local Anesthetics leads to peripheral nerve pain, Post-surgical pain, bursitis, tendonitis, trigger points, reflex sympathetic dystrophy syndrome, Minor surgeries
mechanism: Block pain transmission in peripheral nerves Na channel blockers small diameter fibers most susceptible side effects: Drowsiness, Dizziness, Blurred vision, Slurred speech , Poor balance, (Sounds like a good BOC!) Tingling around lips/mouth, arrhythmias, respiratory depression, seizure notes: Administration: Topical, Transdermal (patch) Infiltration- diffuses to sensory nerve ending Peripheral nerve block – close to nerve trunk Central block- epidural or spinal Sympathetic block –in ganglia, Bier block in selected limb (esp. in RSDS) |
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Morphine
Demerol |
Pain drug
Drug class: Opiates Sub class: Stong agonists Mechanism: Bind µ & d side effects: For opiates in general: many & varied Resp depression Constipation notes: resp depression and euphoria , addictive |
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Codeine
Hydracodone(Vicadin) Oxycodone (Percacet) |
Pain drug
Drug class: Opiates Sub class: Moderate agonists Mechanism: Bind µ & d side effects: Sedation ortho hypo nausea vomiting seizures bradycardia notes: resp depression and euphoria , addictive Have acetominophen |
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Butorphanol (Stadol)
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Pain drug
Drug class: Opiates Sub class: Mixed agonist/anagonist Mechanism: Partial agonist at µ & d, full at k side effects: Hallucinations Nightmares Anxiety notes: no resp depression or euphoria , least addictive (? i don't remember from the quiz--not the same chance for adiction because it doesn't cause the type of euphoric effects that the opiates binding the u and d receptors do.) |
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Naloxone
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Pain drug
Drug class: Opiates Sub class: Antagonist |
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Tramadol (Ultraam)
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Pain drug
Drug class: Opiates Sub class: Misc. Mechanism: Block NE and serotonin also side effects: notes: Not addictive |
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Gabapentin (Neurontin)
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drug class: Atypical Analgesics
sub class: GABA Agonist mechanism: Inhibit ascending trasmission of nerve impulse side effects: Dizzy, fatigue, ataxia, impotence, blurred vision, dry mouth, (agression, emotional lability, hyperkinesia – in kids) notes: Anti seizure med, Also used in MS tremors, bipolar, diabetic neropathy |
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Carbamazepine (Tegretol)
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drug class: Atypical Analgesics
sub class: Other mechanism: blocks polysynaptic reflexes side effects: dizziness, drowsiness, confusion, fatigue tinnitus, dry mouth, blurred vision, nausea, constipation, vomiting notes: Also used in bipolar and schizophrenia, restless leg syndrome, diabetic neuropathy |
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Amitriptyline (Elavil)
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drug class: Atypical Analgesics
sub class: Tricyclic Antidepressants mechanism: prevent reuptake of NE side effects: transient sedation orthostatic hypotension arrhythmias, anticholinergic notes: |
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Aspirin
Salicylic Acid |
Pain and Inflammation Drugs
drug class: Non-Opioid Analgesics sub class: NSAID’s Salicylates mechanism: Inhibit COX I and COX II enzymes to block paths, kill platelet enzymes side effects: GI (pain, peptic ulcer?) Reye’s syndrome in children with viral infection May exacerbate renal and/or hepatic disease Reduced tissue healing High doses cause tinnitus, vertigo, increased ventilation – resp. alkalosis Sensitivity in asthmatics, allergies notes: Used for analgesic anti-inflammatory antipyretic anticoagulant |
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Ibuprofen
Naproxen |
Pain and Inflammation Drugs
drug class: Non-Opioid Analgesics sub class: NSAID’s Non-Salicylates mechanism: Inhibit COX I and COX II enzymes to block paths, don’t affect platelets side effects: fewer GI than aspirin notes: Naproxen closest to COX II inhibitor |
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Celecoxib (Celebrex),
Vioxx |
Pain and Inflammation Drugs
drug class: Non-Opioid Analgesics sub class: COX II Inhibitors mechanism: side effects: fewer side effects than other NSAIDs may increase the risk of upper respiratory infection some GI problems (diarrhea, heartburn, stomach, cramps, bleeding) but fewer incidence than others notes: COX II thought to be important in production of Omega-3 fatty acids, to protect against the formation of blood clots and atherosclerosis. |
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Acetominophen
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Pain and Inflammation Drugs
drug class: Non-Opioid Analgesics sub class: mechanism: May work primarily on central prostaglandins side effects: liver toxicity, do not exceed dosage notes: Antipyretic, analgesic NOT anti-inflammatory NOT anticoagulant effects |
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Short acting-Cortisone
Long acting - Dex |
Pain and Inflammation Drugs
drug class: Non-Opioid Analgesics sub class: Steroids mechanism: side effects: 1. skin breakdown 2. muscle breakdown 3. osteoporosis 4. cataracts 5. elevated blood glucose 6. mood swings and psychosis 7. hypertension 8. adrenal insufficiency notes: |
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sub class: NSAIDS
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Rheumatoid Arthritis Drugs
drug class: sub class: drug: mechanism: side effects: notes: |
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sub class: Corticosteroids
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Rheumatoid Arthritis Drugs
drug class: sub class: drug: mechanism: side effects: notes: (4x /yr inection/joint) or oral |
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sub class: Antimalarials
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Rheumatoid Arthritis Drugs
drug class: DMARDs sub class: drug: mechanism: Inhibit immune system (t and B lymphocytes, cytokines, etc) side effects: Can be toxic notes: disease modifiying antirheumatic drugs retard or stop progression |
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sub class: Gold compounds
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Rheumatoid Arthritis Drugs
drug class: sub class: drug: mechanism: side effects: Can be toxic notes: |
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sub class: Tumor Necrosis Factor (TNF) inhibitors
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Rheumatoid Arthritis Drugs
drug class: sub class: drug: mechanism: side effects: Can be toxic notes: Given by IV |
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Methotrexate (Rheumatrex )
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Rheumatoid Arthritis Drugs
drug class: sub class: Others mechanism: side effects: Can be toxic notes: |
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Salbutamol (albuterol)
Epinephrine Isoproternol |
Asthma and COPD drugs
drug class: Bronchodilators sub class: Beta 2 agonists mechanism: side effects: notes: |
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Theophylline (areolate)
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Asthma and COPD drugs
drug class: Bronchodilators sub class: Xanthine Derivatives mechanism: May inhibit Phosphodiesterase side effects: GI, confusion, irritability arrhythmias, seizures notes: |
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Ipratroprium (Atrovent)
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Asthma and COPD drugs
drug class: Bronchodilators sub class: Anticholinergics mechanism: Block M receptors (like atropine) Side effects: Bad b/c block M receptors (can’t see, can’t pee, can’t poop, can’t something else), less with inhaled drug notes: |
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Cortisone (Cortone)
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Asthma and COPD drugs
drug class: Anti-inflammatory sub class: Glucocorticoids mechanism: Side effects: fewer with inhaled notes: |
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Drug Type: Tricyclics
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Amitriptyline
Elavil |
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Trycyclics
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Depression
Analgesia |
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MAO Inhibitors
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Phenelezine
Selegeline |
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MAO Inhibitors Uses
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Depresion (NE)
Parkinsons (DA) |
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SSRI's
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Paroxitine
Sertraline Paxyl Zoloft Welbutrin |
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SSRI's Uses
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Depression
Anxiety |
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Benzodiazepenes
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Xanax
Valium Ativan Klonopin halcion lorazapam |
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Benzo Uses
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Anxiety
Situational Depression Muscle Spasm/Spasticity (valium) Status Epilepticus also other anti seizure sedation adjuvant anesthetic |
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Azapirones
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Buspar
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Azapirones uses
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Anxiety
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Barbituates
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Phenobarbitol
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Barbituates Uses
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seizure
status epilepticus sedation adjuvant anesthetic |
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a-2 agonist
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zanaflex
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a-2 agonist uses
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anxiety
spasticity |
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DA Antagonists
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Haldol (high Potency)
Thorazine (low potency) Risperidal (atypical) |
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DA Antagonsits uses
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bipolar disorder
psychosis antacid |
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antiseizure meds
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iminostilbenes-tegretol
2nd gen.- neurontin succinimides-Zarontin Valproic Acid barbs benzos succinimides hydontoins |
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Anti-seizure meds uses
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bipolar disorder
spasticity seizures (hopefully this was obvious) pain inflammation Investigational: diabetic Neuropathy RLS Schizophrenia |
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anticholinergics uses
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Parkinson's
Asthma/COPD Control Gastric Acidity Antiemetic |
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Antihistamine
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Benadryl
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Antihistamine uses
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sedation
adjuvant antiemetic (H2 receptor) |
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Opiates
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Fentanyl
Morphine Codeine Nubrin Stadol Ultraam |
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Opiates Uses
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Anesthesia
Analgesia Diarrhea |
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Glucocorticoid uses
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analgesic
adjuvant asthma/COPD Rheumatoid Arthritis |
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NSAIDS **
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Analgesic ** (inflammation not controlled c acetomenophin)
anticoag/antipyretic Rheumatoid Arthritis |