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108 Cards in this Set

  • Front
  • Back
Amitriptyline
Antidepressants, Pain

Class: Tricyclics
Mechanism: Block reuptake NE which leads to A2 downreg., also works on serotonin receptors
Side Effects: sedation, anticholinergic (dry eyes, mouth, constipation, blurred vision) OH, seizures
Phenelzine
Antidepressants

Class: MAO Inhibitors
Mechanism: Block degradation of NE in axon terminal which leads to more NE available to release
Side Effects: restlesness, agitation, anticholinergic
Notes: Used for PARKINSONS
Nasty drug
Many Contrainds: don’t take w cold meds (CV crisis) or cheese, choc, wine (have tyromine)
Paroxetine (Paxil)
Zoloft
Prozac
Antidepressant

Class: SSRI – Selective serotonin reuptake inhibit.
Mechanism: Block reuptake Serotonin
Side Effects: same as tricyclics, but less severe
slight resting tremor
Notes: Can be used for OCD and anxiety as well. May be given w sedative b/c tremors.
Wellbutrin (Bupropion)
Antidepressants

Class: others
Mechanism: Acts like dopamine
Side effects: tremor, seizure, psychosis
Xanax
Clonazapam
Diazepam (Valium)
Lorazepam (Ativan
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)

Class: Benzodiazepines
Mechanism: GABA opens channel to kept open longer to more hyperpolarization
Side Effects: Sedation, muscle weakness, dependence
Notes: See pt at valley

(also used for anti-seizure, anti-anxiety, sedation, spasm, spasticity, and anesthetic)
Buspirone (Buspar)
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)

Class: Azapirones
Mechanism: Serotonin Agonist
Side Effects: less sedation, tolerance, dependance
Notes:
Cymbalta
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)

Class: SSRI AND Tricyclic
Mechanism: Blocks reuptake NE and Seratonin
Side effects:
Notes:
Antianxiety drugs:

Class: Beta Antagonist
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)

mechanism: Block B1 receptors,
Works more in PNS
side effects: Decrease HR
notes: When need to reduce anxiety is certain situations (performer)
Antianxiety drugs:

Class: Alpha 2 Agonist
Antianxiety drugs: panic disorder, OCD, posttraumatic stress syndrome (biochemical issues)

Mechanism: Works more in PNS
side effects: Decrease all SNS effects
notes: When need to reduce anxiety is certain situations (performer)
Lithium
Treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression

mechanism: mechanism unclear, may mimic Na
side effects: Tremor (fine in low dose, course in high)
Muscle weakness, respiratory depression
Confusion, lack of concentration, nystagmus
Resperidone (Risperdal)
treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression

class: Selective Dopamine Antagonists
mechanism: Inhibit DA receptors in limbic system (not ones in basal ganglia)
side effects: Progression:
anticholinergic (less)
Parkinsonism (less)
Tardive dyskenesia (less)
Sedation (less)
notes: increase dose leads to increase risk of side effects
Carbamazepine (Tegretol)
treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression

class: Antiseizure Meds
mechanism: blocks Na+ channels to prevent AP
Gabapentin (Neurontin)
treats Bipolar Disorder: Mania leads to incr. NT, Depression leads to decr. NT, Tx=stabilize mania neurons, Mania leads to provokes depression

mechanism: GABA release
side effects: Sedation, Fatigue, Ataxia
notes: Not really a GABA agonist
Dopamine Antagonists:

Halodol
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.

class: High Potency
mechanism: Block ALL DA receptors
side effects: Mostly motor dysfunction. strongly extrapyramidal , some anticholinergic, sedation, orthostatic hypotension
notes: Extrapyramidal = dystonia, akathesia (pacing?), parkinson symptoms, dyskinesias
80’s
Dopamine Antagonists:

Chlorpromazine (Thorazine)
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.

class: Low Potency
mechanism: Non-selective
side effects: strongly anticholinergic, some extrapyramidal, sedation, orthostatic hypotension
notes: 50’s
Dopamine Antagonists:

Clozapine (Clozaril), Resperidone (Risperdal),
Antipsychotic Meds: Psychosis = group of mental disorders (thought disturbances (paranoia), impaired perception of reality, schizophrenia (no longer care)). Genetic predisposition. Dopamine Theory = too much Dopamine in limbic system.

class: Atypical Agents
mechanism: Selective for DA receptors in limbic system
side effects: less frequency and intensity of above
notes: Side effects are dose dependent.
Sinemet
Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)

Side effects: arrhythmias, GI dysfunction (peripheral)
dyskinesia, psychotic like behavior (central)
notes: combination of l-dopa and carbidopa
class: dopamine agonists
Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)

side effects: too many peripheral side effects
notes: selective drugs offer fewer side effects:
( Mirapex, ReQuip)
Atropine
Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)

class: Anticholinergic
notes: Help reduce resting tremor
class: MAO inhibitor
Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)

mechanism: prevents the break down NE
Symmetrel
Movement Disorders Meds: Normal Pressure Hydrocephalus(gait, balance, incontinence, cognition), Alzheimer’s (cognition, motor dysfunction), Parkinson’s (tremor, rigidity, bradykinesia, gait, balance)

class: Amantadine
mechanism: Antiviral agent
Triazolam (Halcion)
Sedatives (relax) and Hypnotics (sleep):

class: Benzodiazepines
mechanism: inhibit neurons in reticular formation
bind all 3 subunits of GABA A (Alpha 1- sedation
Alpha 2 & 3- antianxiety. dependance )
side effects: drowsy, muscle weakness, “hangover”
notes:
Barbiturates - Phenobarbital
Sedatives (relax) and Hypnotics (sleep):

class: Non-Benzodiazepines
mechanism: bind GABA A (reticular formation, limbic)
may increase glycine
at high doses, depress neurons
in higher brain centers (anesthesia)

side effects: “hangover”, muscle weakness,
Small Therapeutic Index leads to death if exceed

notes: tolerance, dependency
Zolpidem (Ambien)
Sedatives (relax) and Hypnotics (sleep):

class:
mechanism: Appear to bind only the Alpha 1 subunit of GABA A
side effects: Fewer side effects
notes: Newer
Dependency not a problem
Antihistamines - Benadryl
Sedatives (relax) and Hypnotics (sleep):

class:
mechanism: First Generation drugs enter CNS and decrease Histamine release from nerve terminals
side effects:
notes: Become desensitized after 3 days
FOR SPASMS:

Diazepam (Valium)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class: Benzodiazepines
mechanism: GABA mechanism
side effects: sedation, generalized weakness
notes:
FOR SPASMS:

Skelaxin, Skelex (don’t need to know)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class: Polysynaptic Inhibitors
mechanism:
side effects:
notes: several interneurons involved in reflex at spinal cord
FOR SPASTICITY:

Baclofen (oral)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: Binds GABA B- inhibition of alpha motor neurons in spinal cord--keep K+ channels open
side effects: muscle weakness, fatigue, drowsiness, in CVA and elderly to confusion and hallucinations
notes:
FOR SPASTICITY:

Baclofen (pump)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: Intrathecal to delivery to subarachnoid space
side effects: less systemic effects, fewer hallucinations in CVA, elderly
notes: For severe spasticity
lower doses
FOR SPASTICITY:

Diazepam (Valium)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism:
side effects:
notes: USED FOR BOTH
FOR SPASTICITY:

Gabapentin (Neurontin)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: inhibits alpha motor neuron
mechansim unclear- not same receptors as GABA

side effects: sedation, fatigue, dizziness, ataxia
notes:
FOR SPASTICITY:

Tizanidine (Zanaflex)
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: Alpha 2 agonist to Inhibits interneurons that are stimulatory to alpha motor neurons, block NE release
side effects: sedation, dizziness, dry mouth
less generalized weakness than other relaxants less cardiac effects than clonidine

notes:
FOR SPASTICITY:

Botulinum Toxin
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: Destroys SNARE proteins at NMJ therefore vesicles can’t release NT
side effects: Respiratory depression
notes: Direct Acting, Injection into site ~ 3 month intervals, also used for hyperactive bladder with CVA, better fit of orthotics, cosmetic
FOR SPASTICITY:

Dantrolene Sodium
Muscle Relaxants: brain injury or SCI leads to spasticity leads to exaggerated stretch reflex, orthopedic injury to muscle or peripheral nerve root leads to spasm leads to tonic contraction

class:
mechanism: Blocks release of Ca++ from SR to no contraction
side effects: muscle weakness, hepatotoxicity , drowsiness, dizziness
notes: Direct Acting, also used for Malignant Hyperthermia (increased Ca release to very strong contractions leads to temp rise)
Phenobarbital
Seizure Meds:

class: Barbiturates
mechanism: Increase GABA effects
side effects: (tolerance, dependence)
Sedation, weakness, hyperactivity in some

notes:
Clonazepam (klonopin)
Seizure Meds:

class: Benzodiazepines
mechanism: Increase GABA effects
side effects: (tolerance, dependence)
Sedation, weakness,

notes:
class: Hydantoins
Seizure Meds:

class:
mechanism: slow recovery of Na+ channels in rapidly firing neurons
side effects: Sedation, dizziness, hirsutism, headache
notes: often first choice for partial, tonic-clonic
Carbamazepine (Tegretol)
Seizure Meds:

class: Iminostilbenes
mechanism: slow recovery of Na+ channels in rapidly firing neurons
side effects: Dizziness, drowsiness, water retention (ADH), CHF, arrhythmia
notes: Treats all but absence seizure
class: Succinimides-
Seizure Meds:

class:
mechanism: slow recovery of Na+ channels in rapidly firing neurons
side effects: Sedation, dizziness, hirsutism, headache
notes: often first choice for partial, tonic-clonic
class: Valproic Acid
Seizure Meds:


mechanism: Increases GABA at high dose Still works at low dose withouut GABA but ?????
side effects: GI distress, hirsutism,wt gain or loss
notes: Treats absence or as secondary in tonic/clonic
Felbatol
Seizure Meds:

class: Felbamate-
mechanism: blocks actions of glutamate
side effects: NOT BETTER, BUT FEWER SIDE EFFECTS?
notes: Second Generation Drugs
Neurontin
Seizure Meds:

class: Gabapentin
mechanism: GABA agonist? Increases GABA release?
side effects: NOT BETTER, BUT FEWER SIDE EFFECTS?
notes: Second Generation Drugs
Lamictal
Seizure Meds:

class: Lamotrigine
mechanism: stabilizes Na+ channels
side effects: NOT BETTER, BUT FEWER SIDE EFFECTS?
notes: Second Generation Drugs
Topomax
Seizure Meds:

class: Topirimate
mechanism: inhibits Na+. Increases GABA, blocks glutatmate action
side effects: NOT BETTER, BUT FEWER SIDE EFFECTS?
notes: Second Generation Drugs
Benzodiazepines
Phenytoin
phenobarbital
Status Epilepticus Drugs: Series of seizures without recovery period
Caused by Sudden withdrawal of anti-seizure medication, cerebral infarct, Alcohol withdrawal

notes: IV
Diazepam (Valium), Lorazepem (Ativan)
General Anesthetics- IV: rapid onset, less control, CNS depressants

class: Benodiazepines-
mechanism:
side effects:
notes:
Thiopental (truth serum)
General Anesthetics- IV: rapid onset, less control, CNS depressants

class: Barbiturates
mechanism:
side effects:
notes:
Ketalar
General Anesthetics- IV: rapid onset, less control, CNS depressants

class: Ketamine
mechanism: dissociative anesthesia, inhibits glutamate
side effects:
notes: for short procedures
Fentanyl+Droperidol
General Anesthetics- IV: rapid onset, less control, CNS depressants

class: Opiate + Antipsych
mechanism: dissociative without loss of consciousness
side effects:
notes:
Propofol (Diprivan)
General Anesthetics- IV: rapid onset, less control, CNS depressants

class: Short acting hypnotic
mechanism: GABA mechanism
side effects:
notes: lots of this in trauma centers
Halothane
General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV!

class: Halogenated volatile liquids-
mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia)
Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli)
Interfere with Na+ channel?
GABA binding, ACH inhibition?

side effects: Confusion, muscle weakness,
Lethargy, respiratory depression

notes:
desflurane
General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV!

class: Halogenated volatile liquids-
mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia)
Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli)
Interfere with Na+ channel?
GABA binding, ACH inhibition?

side effects: Confusion, muscle weakness,
Lethargy, respiratory depression

notes: Newer drugs- faster onset, recovery
Nitrous oxide
General Anesthetics- Inhalation: longer onset, better control, Gas or Volatile liquid mixed with air or O2, Lipid Soluble, Widely distributed, Stored in adipose, slow release, elderly affected, Little metabolism of inhalation anesthetics, Excretion of inhalation via lungs
Usually use in combination w IV!

class: Gas anesthetic
mechanism: Inhibit neuronal activity in RAS (unconsciousness, amnesia)
Inhibit neuronal activity in spinal cord (immobility, inhibit painful stimuli)
Interfere with Na+ channel?
GABA binding, ACH inhibition?

side effects: Confusion, muscle weakness,
Lethargy, respiratory depression

notes: shorter procedures
Pancuronium, Tubocurrarine
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class: Nondepolarizing agents
mechanism: Block Nicotinic receptors (competitive antagonists)
side effects: Both lead to muscle paralysis,
increase histamine release and affect lungs

notes:
Succinylcholine (Anectine)
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class: Depolarizing agents
mechanism: Bind N receptor and depolarize muscle, Drug not readily inactivated by cholinesterase
side effects: Both lead to muscle paralysis,
increase histamine release and affect lungs

notes:
opiates, benzodiazepins, barbiturates
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class: Sedatives
mechanism:
side effects:
notes:depends on type of anesthesia
Antihistamines
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class:
mechanism:
side effects:
notes: sedate, reduce vomiting
Antacids
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class:
mechanism:
side effects:
notes: reduce risk of lung injury from aspiration
Anti-inflammatory steroids-
General Anesthetics- Adjuvants: Neuromuscular Junction (NMJ) Blockers (depolarizing or non) to Blocks spontaneous contractions, Intubation easier, Reduces amount of anesthetic
PREOPERATIVE MEDICATIONS

class:
mechanism:
side effects:
notes: help prevent vomiting, pain
class: -Caines
Local Anesthetics leads to peripheral nerve pain, Post-surgical pain, bursitis, tendonitis, trigger points, reflex sympathetic dystrophy syndrome, Minor surgeries

mechanism: Block pain transmission in peripheral nerves
Na channel blockers
small diameter fibers most susceptible

side effects: Drowsiness, Dizziness, Blurred vision, Slurred speech , Poor balance, (Sounds like a good BOC!) Tingling around lips/mouth, arrhythmias, respiratory depression, seizure
notes: Administration:
Topical, Transdermal (patch)
Infiltration- diffuses to sensory nerve ending
Peripheral nerve block – close to nerve trunk
Central block- epidural or spinal
Sympathetic block –in ganglia, Bier block in selected limb (esp. in RSDS)
Morphine
Demerol
Pain drug
Drug class: Opiates
Sub class: Stong agonists
Mechanism: Bind µ & d
side effects: For opiates in general: many & varied
Resp depression
Constipation

notes: resp depression and euphoria , addictive
Codeine
Hydracodone(Vicadin)
Oxycodone (Percacet)
Pain drug
Drug class: Opiates
Sub class: Moderate agonists
Mechanism: Bind µ & d
side effects: Sedation
ortho hypo
nausea
vomiting
seizures
bradycardia

notes: resp depression and euphoria , addictive
Have acetominophen
Butorphanol (Stadol)
Pain drug
Drug class: Opiates
Sub class: Mixed agonist/anagonist
Mechanism: Partial agonist at µ & d, full at k
side effects: Hallucinations
Nightmares
Anxiety

notes: no resp depression or euphoria , least addictive (? i don't remember from the quiz--not the same chance for adiction because it doesn't cause the type of euphoric effects that the opiates binding the u and d receptors do.)
Naloxone
Pain drug
Drug class: Opiates
Sub class: Antagonist
Tramadol (Ultraam)
Pain drug
Drug class: Opiates
Sub class: Misc.
Mechanism: Block NE and serotonin also
side effects:
notes: Not addictive
Gabapentin (Neurontin)
drug class: Atypical Analgesics
sub class: GABA Agonist
mechanism: Inhibit ascending trasmission of nerve impulse
side effects: Dizzy, fatigue, ataxia, impotence, blurred vision, dry mouth, (agression, emotional lability, hyperkinesia – in kids)
notes: Anti seizure med, Also used in MS tremors, bipolar, diabetic neropathy
Carbamazepine (Tegretol)
drug class: Atypical Analgesics
sub class: Other
mechanism: blocks polysynaptic reflexes
side effects: dizziness, drowsiness, confusion, fatigue
tinnitus, dry mouth, blurred vision, nausea, constipation, vomiting

notes: Also used in bipolar and schizophrenia, restless leg syndrome, diabetic neuropathy
Amitriptyline (Elavil)
drug class: Atypical Analgesics
sub class: Tricyclic Antidepressants
mechanism: prevent reuptake of NE
side effects: transient sedation
orthostatic hypotension
arrhythmias, anticholinergic

notes:
Aspirin
Salicylic Acid
Pain and Inflammation Drugs

drug class: Non-Opioid Analgesics
sub class: NSAID’s
Salicylates

mechanism: Inhibit COX I and COX II enzymes to block paths, kill platelet enzymes
side effects: GI (pain, peptic ulcer?)
Reye’s syndrome in children with viral infection
May exacerbate renal and/or hepatic disease
Reduced tissue healing
High doses cause tinnitus, vertigo, increased ventilation – resp. alkalosis
Sensitivity in asthmatics, allergies

notes: Used for analgesic
anti-inflammatory
antipyretic
anticoagulant
Ibuprofen
Naproxen
Pain and Inflammation Drugs

drug class: Non-Opioid Analgesics
sub class: NSAID’s
Non-Salicylates

mechanism: Inhibit COX I and COX II enzymes to block paths, don’t affect platelets
side effects: fewer GI than aspirin
notes: Naproxen closest to COX II inhibitor
Celecoxib (Celebrex),
Vioxx
Pain and Inflammation Drugs

drug class: Non-Opioid Analgesics
sub class: COX II Inhibitors
mechanism:
side effects: fewer side effects than other NSAIDs
may increase the risk of upper respiratory infection
some GI problems (diarrhea, heartburn, stomach, cramps, bleeding) but fewer incidence than others

notes: COX II thought to be important in production of Omega-3 fatty acids, to protect against the formation of blood clots and atherosclerosis.
Acetominophen
Pain and Inflammation Drugs

drug class: Non-Opioid Analgesics
sub class:
mechanism: May work primarily on central prostaglandins
side effects: liver toxicity, do not exceed dosage
notes: Antipyretic, analgesic
NOT anti-inflammatory
NOT anticoagulant effects
Short acting-Cortisone
Long acting - Dex
Pain and Inflammation Drugs

drug class: Non-Opioid Analgesics
sub class: Steroids
mechanism:
side effects:
1. skin breakdown
2. muscle breakdown
3. osteoporosis
4. cataracts
5. elevated blood glucose
6. mood swings and psychosis
7. hypertension
8. adrenal insufficiency

notes:
sub class: NSAIDS
Rheumatoid Arthritis Drugs

drug class:
sub class:
drug:
mechanism:
side effects:
notes:
sub class: Corticosteroids
Rheumatoid Arthritis Drugs

drug class:
sub class:
drug:
mechanism:
side effects:
notes: (4x /yr inection/joint) or oral
sub class: Antimalarials
Rheumatoid Arthritis Drugs

drug class: DMARDs
sub class:
drug:
mechanism: Inhibit immune system (t and B lymphocytes, cytokines, etc)
side effects: Can be toxic
notes: disease modifiying antirheumatic drugs
retard or stop progression
sub class: Gold compounds
Rheumatoid Arthritis Drugs

drug class:
sub class:
drug:
mechanism:
side effects: Can be toxic
notes:
sub class: Tumor Necrosis Factor (TNF) inhibitors
Rheumatoid Arthritis Drugs

drug class:
sub class:
drug:
mechanism:
side effects: Can be toxic
notes: Given by IV
Methotrexate (Rheumatrex )
Rheumatoid Arthritis Drugs

drug class:
sub class: Others

mechanism:
side effects: Can be toxic
notes:
Salbutamol (albuterol)
Epinephrine
Isoproternol
Asthma and COPD drugs

drug class: Bronchodilators
sub class: Beta 2 agonists
mechanism:
side effects:
notes:
Theophylline (areolate)
Asthma and COPD drugs

drug class: Bronchodilators
sub class: Xanthine Derivatives
mechanism: May inhibit Phosphodiesterase
side effects: GI, confusion, irritability
arrhythmias, seizures

notes:
Ipratroprium (Atrovent)
Asthma and COPD drugs

drug class: Bronchodilators
sub class: Anticholinergics
mechanism: Block M receptors (like atropine)
Side effects: Bad b/c block M receptors (can’t see, can’t pee, can’t poop, can’t something else), less with inhaled drug
notes:
Cortisone (Cortone)
Asthma and COPD drugs

drug class: Anti-inflammatory
sub class: Glucocorticoids
mechanism:
Side effects: fewer with inhaled
notes:
Drug Type: Tricyclics
Amitriptyline
Elavil
Trycyclics
Depression
Analgesia
MAO Inhibitors
Phenelezine
Selegeline
MAO Inhibitors Uses
Depresion (NE)
Parkinsons (DA)
SSRI's
Paroxitine
Sertraline
Paxyl
Zoloft
Welbutrin
SSRI's Uses
Depression
Anxiety
Benzodiazepenes
Xanax
Valium
Ativan
Klonopin
halcion
lorazapam
Benzo Uses
Anxiety
Situational Depression
Muscle Spasm/Spasticity (valium)
Status Epilepticus also other anti seizure
sedation
adjuvant
anesthetic
Azapirones
Buspar
Azapirones uses
Anxiety
Barbituates
Phenobarbitol
Barbituates Uses
seizure
status epilepticus
sedation
adjuvant
anesthetic
a-2 agonist
zanaflex
a-2 agonist uses
anxiety
spasticity
DA Antagonists
Haldol (high Potency)
Thorazine (low potency)
Risperidal (atypical)
DA Antagonsits uses
bipolar disorder
psychosis
antacid
antiseizure meds
iminostilbenes-tegretol
2nd gen.- neurontin
succinimides-Zarontin
Valproic Acid
barbs
benzos
succinimides
hydontoins
Anti-seizure meds uses
bipolar disorder
spasticity
seizures (hopefully this was obvious)
pain
inflammation
Investigational:
diabetic Neuropathy
RLS
Schizophrenia
anticholinergics uses
Parkinson's
Asthma/COPD
Control Gastric Acidity
Antiemetic
Antihistamine
Benadryl
Antihistamine uses
sedation
adjuvant
antiemetic (H2 receptor)
Opiates
Fentanyl
Morphine
Codeine
Nubrin
Stadol
Ultraam
Opiates Uses
Anesthesia
Analgesia
Diarrhea
Glucocorticoid uses
analgesic
adjuvant
asthma/COPD
Rheumatoid Arthritis
NSAIDS **
Analgesic ** (inflammation not controlled c acetomenophin)
anticoag/antipyretic
Rheumatoid Arthritis