Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/12

Click to flip

12 Cards in this Set

  • Front
  • Back
Pharmacology
study of interaction of chemical substances with living systems
Drug
Any substance that brings change in biologic function through chemical action
Receptor
Specific regulatory molecule in biologic system where drug interacts - activates or inhibits normal body processes
Agonist
Drug that binds to receptor and stimulates cellular activity
Antagonist
Drug that binds to receptor and inhibits action of agonist - can be drug or endogenous agent
Importance of drug size
Lower limit allows specificity of drug action.
Upper limit determines extent of movement within body
Protein targets for drug binding
1. Receptors
2. Enzymes
3. Carrier molecules
4.Ion channels
5. Structural proteins
6. Plasma proteins
Drugs that are not acting through receptors
Chemical antagonists - binding stoichiometrically
Physiologic antagonists - adrenergic beta blockers
Osmotic agents - mannitol for subarachnoid hemorrhage
DNA - chemo drugs for cancer
Pharmacotherapeutic
Refers to clinical condition for which drug is used
Imprecise - antibacterial, antviral
Precise - antitubercular
Pharmacologic
based on mechanism of the action of the drug including action of drug on system
Pharmacodynamic
Action of drug on body
Pharmacokinetic
Action of body on drug