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5 Cards in this Set
- Front
- Back
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Histamine:
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A compound derived from an amino acid called histidine, stored in small granules in most body tissues & is released in response to allergic reactions and tissue damage from trauma or infection. Reacts w/ H1 receptors (H1 receptor antagonist).
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When large amount of histamine are released:
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1.Extensive arteriolar dilation
2.BP drops 3.Skin becomes flush/edematous 4.Urticaria 5.Constriction/spasm of bronchial tubes. 6.Dyspnea 7.Increased amounts of pulmonary & gastric secretions are released. |
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Rhinitis Medicamentosa
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Drug-induced nasal congestion
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Caution use of antihistamines in pts with?
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DM, HTN, or ischemic heart disease. May also cause urinary retention & caution use in older men w/ enlarged prostate.
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Cromolyn Sodium:
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An antiinflammatory agent that inhibits the release of histamine & other inflammatory agents. Needs to be administered before stimulus activates histamine.
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