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52 Cards in this Set

  • Front
  • Back
Controlled Substance
drugs with a high potential for abuse that are controlled by special regulations/may cause physical or psycological dependence
Drug Enforcement Administration
responsible for enforcing the Controlled Substances Act
The United States Food and Drug Administration
responsible for approving new drugs and monitoring drugs for adverse or toxic reactions
study of drugs and their actions on living organisms
active absorption
when a carrier molecule such as a protein or enzyme actively moves the drug across a membrane
adverse reactions
undesirable drug effects
drugs that bind with a receptor to produce a therapeutic response
drugs that join with a receptor and thereby prevent the action of an agonist/produces no pharmacologic effect
ex: Narcan/blocks effects of Morphine
movement of drugs from the blood into the tissues and cells
the removal of waste products of drugs fromt the body
the physical or chemical alteration of the drug in the body
passive absorbtion
drugs particles within the gastrointestinal tract are moved into body fluids by diffusion(movement from a higher concentration to a lower concentration)
complications of drug therapy
Side Effects
Adverse Reactions
Allergic reactions
drug-drug interaction
drug-food interaction
What are the 7 Rights of Medical Adminsitration
Right Dose
Right Drug
Right Time
Right Route
Right Patient
Right Documentation
Right Technique
What are signs of impairment of Health Care Worker
Change in behavior
Change in appearance
Spend alot of time going to their locker or Car
Trouble completing assignments
Change in Friends
Smell like Alcohol
Drowiness, Sleepiness
Federal Pure Food and Drug Act
required drug manufactures to label medication packages to indicate presence of 11 drugs identified as dangerous or addictive, including opium, morphine, heroin and alcohol
* only drugs sold thru interstate commerce were covered in act
*designated the US pharmacopoeia (USP) and the National Formulary(NF) as documents containing the offical standards by which a drug was to be manufactured
Shirley Amendment
prevented fraudulent therapeutic claims by drug manufacturers
Harrison Narcotic Act
*established word narcotic and required a tax stamp on containers of narcotic drugs
*required minimum standards of strength, purity of quality
*dangerous drugs must be included on label
Food, Drug and Cosmetic Act
*provided safety testing for all durgs, with the FDA responsible for enforcement
Durham-Humphrey Admendment
*specified how prescription drugs could be ordered and dispensed
*required warning labels concerning drowsiness, habit-forming etc...
*legend drugs "caution: federal law prohibits dispensing without prescription"
Kefauver-Harris Amendments
*response to thalidomide effect on fetus
*require proof of both safety and efficacy
*drugs must be safe and effective(OTC as well)
*enforced by the FDA
Comprehensive Drug Abuse Prevention and Control Act
*established DEA as part of Justice Dept
*Drugs with potential for abuse needed control
*5 drug schedules established
*Security measures for those handling controlled substances
*Set limitations on use of controlled substances
*prescribers must register and obtain a DEA number
*enforment by DEA
What are the regulation of Medications
Drug Standards
Drug Purity
Drug Strength
Drug Quality
Drug Effcacy
OTC Medication
Drug Standards
ensure that consumers will receive safe medications and that the drugs are those expected
Drug Purity
specifies the type and concentration of a substance that is allowed to be present in a drug
Drug Strength
concentration or active ingredient in a medication
Identify responsibility related to controlled substances
Loss or theft
Schedule 1 Drugs
*high potential for abuse
*severe physical or psychological dependence
*no accepted medical use
ex: heroin, quaalude, pcp, marijuana
Schedule II Drugs
*high potential for abuse
*severe physcial or psychological dependence, accepted medicinal use with specfic restrictions
ex:opium, codeine, morphine, amphetamines, ritalin
Schedule III Drugs
*moderate potential for abuse
*severe physical or psychological dependence
*accepted medicinal uses
ex: paregoric dodeine combinations, seconal
Schedule IV Drugs
*low potential for abuse
*limited psychological and physcial dependence
*accepted medicinal use
ex: darvon, valium, ativan, halcion
Schedule V Drugs
*limited abuse potential
*abuse may lead to limited physical or psychological dependence
*accepted medicinal uses
ex: small amounts of narcotics(codeine) used as antitussives or antidiarrheals
Chemical Name
identifies the exact chemical compound & it's molecular structure
ex: 2-(4-isobutylphenyl)propionic acid
Trade Name
drug name owned by a specific manufacturer
Generic Name
name given when a manufacturer first proposes it it the FDA for approval
ex: ibuprofen
What are the 4 phases of processing a drugs within the body?
How the body processes drugs
Drugs and their action in the body
effects fo drugs to treat disease
Side Effects
usually mild reactions to a drug e.g. drowisness
Adverse Effects
usually severe and unpredictable e.g. respiratory arrest
Allergic Reactions
antigen-antibody reaction causing hypersensitvity e.g. itching , rash
severe, potentially fatal allergic reaction
critical level of a drug in the body which may lead to adverse reactions e.g. digitoxin toxicity
Drug-Drug Interactions
reaction that may potentiate or antagonize drug action
Drug-Food Interactions
interaction with a food that may change drug action
Describe various forms and routes for drug administration
(tablets, liquid, suspension, capsules, caplets)
(lotions, liniments, ointments, trandermal patches, suppositories, eye/ear drops, inhalants, sprays, intramuscular, intravenous, subcutaneous)
Discuss drug abuse and its effects on health professionals
Drug Misuse
Drug Abuse
Drug Habit
Drug Dependency
Drug Addiction
Drug Quality
ensures that the consumer receives drugs meeting the standards published in the National Formulary
Drug Efficacy
ability of the drug to produce the desired chemical change in the body
a drug with no therapeutic effect
OTC medications
must meet the same standards as legend drugs