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16 Cards in this Set
- Front
- Back
Why is cocaine not a perfect local anesthetic?
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Very short duration of action
Toxicity above 30mg Addicitive if consumed systemically |
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What is the restriction with snorting cocaine?
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Plasma levels are limited by localized cocaine-induced vasoconstriction
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What effect does cocaine have on the vasculature?
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Vasoconstriction (alpha-1)
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How long do acute intoxication signs of crack normally last?
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2 hrs
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How long do acute intoxication signs last in snorted cocaine?
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4-6 hrs
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What sign is generally indicative of cocaine abusers who brush?
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Unilateral abrasions of cervical margins due to vigorous brushing
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How long should treatment be delayed if patient has taken cocaine on the day of treatment?
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At least 6 hrs
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What type of anesthetic should be avoided in cocaine abusers?
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Ester-linked L.A.'s (like Novocaine)
Epinephrine should also be avoided |
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Is Nitrous Oxide safe for cocaine abusers?
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Yes
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What drug is used in a hypertensive emergency and is also used in controlled hypotension during surgery?
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Trimethapan
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What drug is used in the diagnosis of Myasthenia Gravis?
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Edrophonium
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What drug is used in the treatment of Myasthenia Gravis?
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Neostigmine
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What type of NMJ Blocking agent cannot be reverse by AchE inhibitors?
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Non-competitive depolarizing agents (succinylcholine)
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Which non-depolarizing NMB is degraded by Hofmann degradation?
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cis atracurium
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What metabolizes Succinylcholine?
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Pseudocholinesterase
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What is the Drug of Choice for the treatment of Malignant Hyperthermia?
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Dantrolene
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