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16 Cards in this Set

  • Front
  • Back
Why is cocaine not a perfect local anesthetic?
Very short duration of action

Toxicity above 30mg

Addicitive if consumed systemically
What is the restriction with snorting cocaine?
Plasma levels are limited by localized cocaine-induced vasoconstriction
What effect does cocaine have on the vasculature?
Vasoconstriction (alpha-1)
How long do acute intoxication signs of crack normally last?
2 hrs
How long do acute intoxication signs last in snorted cocaine?
4-6 hrs
What sign is generally indicative of cocaine abusers who brush?
Unilateral abrasions of cervical margins due to vigorous brushing
How long should treatment be delayed if patient has taken cocaine on the day of treatment?
At least 6 hrs
What type of anesthetic should be avoided in cocaine abusers?
Ester-linked L.A.'s (like Novocaine)

Epinephrine should also be avoided
Is Nitrous Oxide safe for cocaine abusers?
Yes
What drug is used in a hypertensive emergency and is also used in controlled hypotension during surgery?
Trimethapan
What drug is used in the diagnosis of Myasthenia Gravis?
Edrophonium
What drug is used in the treatment of Myasthenia Gravis?
Neostigmine
What type of NMJ Blocking agent cannot be reverse by AchE inhibitors?
Non-competitive depolarizing agents (succinylcholine)
Which non-depolarizing NMB is degraded by Hofmann degradation?
cis atracurium
What metabolizes Succinylcholine?
Pseudocholinesterase
What is the Drug of Choice for the treatment of Malignant Hyperthermia?
Dantrolene