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23 Cards in this Set
- Front
- Back
Orlistat
-Mechanism |
Alters fat metabolism by inhibiting pancreatic lipase
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Orlistat
-Clinical Use |
Long-term obesity management
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Orlistat
-Toxicity |
Steatorrhea, GI Discomfort, reduced absorption of fat-solube vitamin, headache
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Sibutramine
-Mechanism |
Sympathomimetic serotonin and norepinephrine reuptake inhibitor
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Sibutramine
-Clinical Use |
Short-term and long-term obesity management
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Sibutramine
-Toxicity |
Hypertension and Tachycardia
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Propylthiroauracil
-Mechanism |
A. Inhibits organification and coupling of thyroid hormone synthesis. B. Decreases conversion of T4 to T3 (Methimazole only does A)
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Propylthiorauracil
-Clinical use |
Hyperthyroidism
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Methimazole
-Toxicity |
Same as Propylthiouracil
Skin rash, agranulocytosis, aplastic anemia |
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Somatostatin
-Clinical use |
Acromegaly, carcinoid, gastrinoma, glucagonoma
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Growth Hormone
-Clinical Use |
Turner's syndrome and GH deficiency
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Oxytocin
-Clinical Use |
Stimulates labor, uterine contractions, milk let-down; controls uterine hemmorrhage
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Desmopressin
-Clinical Use |
Pituitary (central, not nephrogenic) DI (ADH)
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Levothyroxine
-Mechanism |
Thyroxine replacement
Also triiodothyronine |
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triiolodthyronine
-Clinical use |
Hypothyroidism, myxedema
Same as Levothyroxine |
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Triiodothyronine
-Toxicity |
Tachycardia, heat intolerance, tremors, Arrhythmias
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Glucocorticoids (-thasone)
-Mechanism |
Decreases the production of leukotrienes and prostaglandins by inhibiting phospholipase A2 and the expression of Cox-2
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Hydrocortisone
-Clinical use |
Glucocorticoid
Addison's disease, inflammation, immune suppression, asthma |
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Triamcinolone
-Toxicity |
Iatrogenic cushing's syndrome-->Buffalo hump, moon facies, truncal obesity, muscle wasting, thin skin, easy bruisability, osteoporosis, adrenocortical atrophy, peptic ulcers, diabetes
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Demeclocycline
-Mechanism |
ADH antagonist (tetracycline family)
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Demeclocycline
-Clinical use |
Diabetes Insipidus, SIADH
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Demeclocycline
-Toxicity |
Photosensitivity, abnormalities of bone and teeth
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Megestrone
-Clinical use |
Used for weight gain (synthetic oral progrestin)
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