Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
Define drug abuse:
|
nonmedical drug use. Any use that deviates from the approved medical or social patters within a culture.
|
|
|
Define compulsive drug use:
|
preoccumpation with use and procurement of a drug. Individual feels that the drug is needed to continue well being.
|
|
|
Define addiction:
|
behavioral pattern of compulsive drug use. Overwhelming involvement with the use of a drug. High tendency to relapse after withdrawal. Should imply extreme compulsive use and phychological dependence. Not just physiological.
|
|
|
Physiological dependence
|
altered physiological state as a result of chronic drug use.
|
|
|
Tolerance
|
more drug is needed to elicit the same response or a reduced response is elicited by the same dose. Could be brought about by pharmacokinetic or delivery issues. Also could be functional tolerance where response is not as great.
|
|
|
Acute tolerance
|
Rapid pharmacodynamic tolerance. Seen in alcohol use.
|
|
|
Reverse tolerance or sensitization
|
Intermittent exposure causes a progressive increase in the sensitivity to drugs.
|
|
|
Phychological dependence
|
individual feels that the effects of a drug or the conditions associated with its use are necessary to maintain an optimal state of well being.
|
|
|
Positive reinforcement
|
drug induces euphoria or other pleasurable effects
|
|
|
Negative reinforcement
|
drug terminates pain, anxiety or withdrawal distress
|
|
|
CNS stimulants receptors
(cocaine, amphetamine, methylphenidate, appetite suppressants) |
Block dopamine and NE reuptake transporter
|
|
|
Nicotine receptor
|
nicotinic acetycholine receptor
|
|
|
Cannabinoids (marijuna)
|
cannabinoid receptor. Use for glaucoma, emmetic effect of ehmo, and analgesic for M.S.
|
|
|
Psychedelic receptors (mescaline, LSD, psilocybin)
|
5-HT receptor
|
|
|
Arylcyclohexylamines receptor (PCP and ketamine)
|
sigma receptor
|
|
|
Inhalants receptor (MDMA- ecstacy)
|
Serotonin recepttor
|
|
|
Drug abuse treatments that cause drugs to have no consequence
|
Methadone and LAAM. Mu agonist. Also nicotin patches and such.
|
|
|
Drug abuse treatment that cause drugs effect to be blocked.
|
Naltrexone and buprenorphine (partial mu agonist that reduces craving)
|
|
|
Drug abuse treatment that causes drug to be a punishment
|
Disulfiram. Inhibits aldehyde dehydrogenase that causes nausea and vomiting while drinking
|
