Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
T/F
Electrolytes have a broad range of functioning |
F
electrolytes are rigidly controlled in a narrow range via reabsorption and excretion in the nephron |
|
______is any damage to the nephron
|
nephrotoxicity
|
|
the deposition of a colloid along the basement membrane of the nephron is an example of _____
|
obstructive assault --> nephrotoxicity
|
|
list the 2 types of assault possible to cause nephrotoxicity
|
obstructive
enzymatic |
|
give an example of enzymatic damage on the nephron
|
chemical damage to active transport pumps in the tubular membrane
|
|
T/F
Diuretics work indirectly on the KD and can cause harm if not monitored properly |
F
Diuretics work DIRECTLY on the KD and can cause harm if not monitored properly |
|
weak diuretic action and more known for its stimulant effect
|
xanthines
metab effected by other meds |
|
Particular caution must be taken when prescribing Thiazides to px
a) Post menopausal b) LV Disease c) Diabetics |
Diabetes- thiazides increase release of glucose by the LV and can cause hyperglycemia
|
|
the greatest caution associated with xanthines especially in pill form
a) headache b) insomnia c) easily dehydrated |
easily dehydrated
(also, metab will be affected by other drugs) |
|
The Major side affects of Thiazides are typically due to
a) Renal Failure b) Electrolyte Imbalance c) Volume Depletion |
Electrolyte Imbalance & Volume Depletion
loss of Na+, Cl-, H+, K+, Ca++ Retention (causes KD Stones) esp Hypokalemia!! |
|
Patients on thiazides often complain of achey muscles, why?
|
due to Hypokalemia
px must be on K+ supplements but they are often huge nasty pills that ppl dont want to take |
|
Thiazide like drug
a) methyclothiazide (Duretic) b) acetazolamid (diamox) c) clorthalidone (Hygroton) |
clorthalidone (Hygroton)
methyclothiazide (Duretic)- thiazide acetazolamid (diamox)- carbonic anhydrase inhibitor |
|
Which of the following is not likely to cause KD stones
a) spironolactone (Aldactone) b) acetazolamide (diamox) c) chlorothiazide (Diuril) |
spironolactone (aldactone)
|
|
Will cause Hyperkalemia
a) spironolactone (aldactone) b) indapamide (lozol) c) triamterene (dyrenium) d) furosomid (lasix) |
spironolactone (aldactone)
triamterene (dyrenium) |
|
T/F
loop diuretics are the most powerful but slow acting |
F
loop diuretics are powerful and FAST acting- used as IV for emergency situations |
|
for emergency pulmonary edema and hypervolemia, which drug would be administered?
a) furosemide (lasix) b) indapamide (lozol) c) spironolactone (aldactone) |
furosemide (lasix)
|
|
taken orally for maintenance of congestive HT failure
a) acetazolamide (diamox) b) metolazone (zaroxolyn) c) furosemide (lasix) d) chlorthalidone (hygroton) |
furosemide (lasix)
|
|
diuretic also known for its anti-convulsant properties
a) Thiazides b) loop diuretics c) carbonic anhydrase inhibitors d) xanthines |
carbonic anydrase inhibitors
acetazolamide (diamox) |
|
Diuretic with vasodilating function
a) indapamide (lozol) b) triamrerene (dyrenium) c) metolazone (zaroxolyn) |
inapamide (lozol)
major adverse affects- dehydration and hypokalemia |
|
works by antagonizeing aldosterone
a) indapamide (lozol) b) triamrerene (dyrenium) c) spironolactone (aldactone) |
spironolactone (aldactone)
adverse affects- Hyperkalemia, gynecomastia, menstrual disturbance, dehydration, mycardial flaccidity |
|
causes alkaline urine, and can cause hyperchloremic acidosis
|
carbonic anhydrase inhibtor
acetazolamide (diamox) also causes KD stones |
|
diuretic that can also be used as a treatment for Glaucoma
|
carbonic anhydrase inhibtor
acetazolamide (diamox) HCO3 excretion decreases secretion of aqueous humor in the eye to lower intra-ocular pressure |
|
diuretic that can cause asymptomatic gout
a) chlorthalidone (hygroton) b) acetazolamide (diamox) c) aminophyllin d) triamterene (dyrenium) |
carbonic anhydrase inhibtor causes Hyperuricemia
acetazolamide (diamox) |
|
Diuretic not used frequently bc it causes aplastic anemia and hepatitis
a) metolazone (zaroxolyn) b) chlorthalidone (hygroton) c) trichlormethiazide (naqua) |
metolazone (zaroxolyn)
|