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40 Cards in this Set
- Front
- Back
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What are the types and specific coticosteriods?
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Glucocorticoids - cortisol
mineralcorticoids - aldosterone androgens - testosterone, estradiol |
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What are the functions of glucocorticoids?
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fat metabolism
CHO metabolism Protein metabolism anti-inflammatory immunosuppressive |
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What is the function of mineralocorticiods?
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maintain fluid and lyte balance
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What is the function of androgens?
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Sex characteristics
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Corticosteriods are secreted from what part of the adrenal gland?
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The cortex
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What are the types and specific coticosteriods?
|
Glucocorticoids - cortisol
mineralcorticoids - aldosterone androgens - testosterone, estradiol |
|
|
What are the functions of glucocorticoids?
|
fat metabolism
CHO metabolism Protein metabolism anti-inflammatory immunosuppressive |
|
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What is the function of mineralocorticiods?
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maintain fluid and lyte balance
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What is the function of androgens?
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Sex characteristics
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Corticosteriods are secreted from what part of the adrenal gland?
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The cortex
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What are the types and specific coticosteriods?
|
Glucocorticoids - cortisol
mineralcorticoids - aldosterone androgens - testosterone, estradiol |
|
|
What are the functions of glucocorticoids?
|
fat metabolism
CHO metabolism Protein metabolism anti-inflammatory immunosuppressive |
|
|
What is the function of mineralocorticiods?
|
maintain fluid and lyte balance
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What is the function of androgens?
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Sex characteristics
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Corticosteriods are secreted from what part of the adrenal gland?
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The cortex
|
|
|
What are the types and specific coticosteriods?
|
Glucocorticoids - cortisol
mineralcorticoids - aldosterone androgens - testosterone, estradiol |
|
|
What are the functions of glucocorticoids?
|
fat metabolism
CHO metabolism Protein metabolism anti-inflammatory immunosuppressive |
|
|
What is the function of mineralocorticiods?
|
maintain fluid and lyte balance
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What is the function of androgens?
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Sex characteristics
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Corticosteriods are secreted from what part of the adrenal gland?
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The cortex
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Aldosterone tells the body to ___________ to fluids which (exacerbates/inhibits) further renin-angiotension release.
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HOLD ON TO
inhibits |
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What are some of the therapeutic uses of corticosteriods?
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Endocrine disorders, rheumatic disorders, dermatologic disorders, allergic conditions, opthalmic disorders, neoplastic diseases, GI diseases (crohns) rispiratory diseases, immunosuppression, unlabled uses
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What are the implications behind the A/E of adrenal suppression?
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Some pts may see a decreased secretion of endogenous corticosteriods after prolonged use of corticosteriods. This is dose dependent. Watch for s/s of adrenal insufficiency (nausea, fatigue, hypotension, hypoglycenia, myalgia, fever, dizziness.)
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How would musculoskelegal A/E resulting from corticosteriods manifest?
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Muscle wasting and weakness, osteoporosis, vertebral compression fractures.
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Would you see an immune reponse resulting from corticosteriod use?
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Yes, possible suppression of immune responses.
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What endocrine-related a/e might you see in a pt on glucocorticoids?
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cushings syndrome, growth suppression, amenorrhea, hyperglycemia, exacerbate diabetes mellitis
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What are the fluid/lyte imbalance a/e to expect?
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Na and H2O retention->edema, hypokalemia, alkalosis, hypertension, CHF
Hypocalcemia |
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Any ocular a/e?
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increased ocular pressure-->cataracts, glaucoma, optic nerve damage, blindness
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GI a/e?
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Pancreatitis, ulcerative esophagitis, peptic ulcers
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CNS a/e?
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Mental disturbances, headache, vertigo, insomnia, seixures, increased ICP
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Dermatologic a/e?
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impaired wound healing, hirsutism, petechiae and ecchymoses
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hypersensitivity a/e?
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Allergic rxn, hives, itching burning
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cardiovascular a/e?
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hypokalemia -> arrhythmias
worsening htn emboli left ventricular free wall rupture after MI |
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What are precautions and contraindications for glucocorticoids?
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pregnancy
lactation children-->impaired growth infections postMI, infection, hypersensitivity, PUD |
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What are the short acting CS?
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Cortisone
hydrocortisone |
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What are the intermediate acting CS?
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Prednisone
Prednisoline triamcinolone methylprednisolone |
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When should GC be given?
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Prior to 9am
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Dosage depends upon:
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diagnosis
severity of disease patient response |
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Why would one suggest alternate day therapy with GCs?
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For pts on long term therapy it may reduce side effects.
Use intermediate acting ones. |
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When d/cing Gcs, what should one do?
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Gradually taper the dose.
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