Pharmacology Ch. 6

Front 1

Chemical name , Generic name , offical name , brand name ?

Back 1

Drug names

Front 2

Plants , animals minerals and Laboratory ?

Back 2

Main sources of drugs

Front 3

How the drug is absorbed , distributed , and eliminated?

Back 3

Pharmacokinetics

Front 4

Enacted to improve the quality and labeling of drugs?

Back 4

Pure food act of 1906

Front 5

Limited the indisriminate use of addicting drugs?

Back 5

The Harrison Narcotic act of 1914

Front 6

Empowered the FDA to enforce standards ?

Back 6

The federal food , drug and cosmetic act of 1938

Front 7

High abuse , no accepted medical indications?

Back 7

Schedule 1

Front 8

High abuse , Accepted medical indications?

Back 8

Schedule 2

Front 9

Less abuse than 1 & 2 , low dependance?

Back 9

Schedule 3

Front 10

Low abuse , limited dependance?

Back 10

Schedule 4

Front 11

Low abuse compared to 4, limited physical dependance?

Back 11

Schedule 5

Front 12

Test that determines the amount and purity of a given chemical in a preparation?

Back 12

Assay

Front 13

Relative effectivness of chemically equivalent drug?

Back 13

Bioequivalence

Front 14

Test to ascertain a drugs availability in a biological model?

Back 14

Bioassay

Front 15

Six Rights of Medication?

Back 15

Right person , right drug , right dose , right time , right route , right documentation.

Front 16

Medications that may deform or kill a fetus?

Back 16

Teratogenic

Front 17

How a drug interacts with the body to cause its effect?

Back 17

Pharmacodynamics

Front 18

Process in which carrier proteins transport large molecules accross the cell membrane?

Back 18

Facilitated diffusion

Front 19

Movement of a substance without energy ?

Back 19

Passive transport

Front 20

Movement of a solute in a solution from a area of higher to lower concentration ?

Back 20

Diffusion

Front 21

Movement of a solute in a solution from an area of lower to higher?

Back 21

Osmosis

Front 22

Movement of molecules accross a membrane from an area of higher pressure to an area of lower pressure?

Back 22

Filtration

Front 23

Amount of a drug that is still active after it reaches its target tissue?

Back 23

Bioavailability

Front 24

Tight junction of capillaries in the central nervous system vasculature?

Back 24

Blood-Brain barrier

Front 25

Special name given to the metabolism of drugs?

Back 25

Biotransformation

Front 26

Medication that is not active when administered but who's biotrans converts it into active metabilites?

Back 26

Prodrug

Front 27

The livers partial of complete inactivation of a drug ?

Back 27

First-pass effect

Front 28

The loss of a hydrogen atom or the acceptance of an o2 atom? Increases positive charge?

Back 28

Oxidation

Front 29

The breakage of a chemical bond by adding water?

Back 29

Hydrolysis

Front 30

Delivery of a medication through the gastrointestinal tract?

Back 30

Enternal route

Front 31

Delivery of medication outside the gastrointestinal tract?

Back 31

Parenternal route

Front 32

Binding of a drug to a target cell or receptor?

Back 32

Down-regulation

Front 33

A drug causes the the formation of more receptors than normal?

Back 33

Up-regulation

Front 34

Drug that binds to a receptor and causes it to initiate the expected response?

Back 34

Agonist

Front 35

Drug that binds to a receptor but does not cause it to initiate the expected response?

Back 35

Antagonist

Front 36

Drug that binds to a receptor and causes some of its effect?

Back 36

Agonist-Antagonist

Front 37

Drug that binds to a receptor and causes the expected efect while blocking another drug?

Back 37

Competitive antagonism

Front 38

The binding of the antagonist causes a deformity of the binding site?

Back 38

Noncompetitive antagonisim

Front 39

A competitive antagonist that permanetly binds to a receptor site?

Back 39

Irreversible antagonism

Front 40

A drug effect that is unique to the individual?

Back 40

Idiosyncrasy

Front 41

Tolerance of a drug that developes after administration of a different drug?

Back 41

Cross tolerance

Front 42

Rapidly occuring tolerance of a drug?

Back 42

Tachyphylaxis

Front 43

Increased effectiveness when a drug is given in serval doses?

Back 43

Cumulative effect

Front 44

The effects of one drug blocks the effects of another?

Back 44

Drug interaction

Front 45

Two drugs that both have the same effect are given ?

Back 45

Summation

Front 46

One drug enhances the effect of another?

Back 46

Potentiation

Front 47

Two drugs , same effect , enhances the effects?

Back 47

Synergism

Front 48

The direct biochemical reaction between two drugs?

Back 48

Interference

Front 49

Correlation of different amounts of a drug to a clinical response?

Back 49

Drug response relationship

Front 50

Desribes the length of onset , duration , and termination of action as well as a drugs minimum effect?

Back 50

Plasma level profile

Front 51

The time a medication reaches its effect concentration?

Back 51

Onset of action

Front 52

Minimum of a drug needed to cause an effect?

Back 52

Minimum effective concentration?

Front 53

Length of time the amount of drug remains above the minimum effective concentration?

Back 53

Duration of action

Front 54

Time from when the drug drops below its minimum concentration till its eliminated from the body?

Back 54

Termination of action

Front 55

Ratio of drugs lethal dose for 50% of the population to is effective dose for 50% of the population?

Back 55

Theraputic index

Front 56

Time the body takes to clear half the drug ?

Back 56

Biologic half-life

Front 57

Factors affecting drug response?

Back 57

Age, body mass, sex, evvironment, time of administration , pathology , genetics , psychology

Front 58

Nerve cell?

Back 58

Neuron

Front 59

Medication that releives the sensation of pain ?

Back 59

Analgesic

Front 60

The absense of the sensation of pain ?

Back 60

Anagesia

Front 61

The absense of all sensation ?

Back 61

Anesthesia

Front 62

Agent that enhances the effects of of other drugs?

Back 62

Adjunct medication

Front 63

Medication that induces a loss of sensation to touch or pain ?

Back 63

Anesthetic

Front 64

Anesthesia that combines decreased sensation of pain with amnesis while the patient remains conscious?

Back 64

Neuroptanesthesia

Front 65

Decreases the the sensory neurons ability to propagate pain impulses? Morphine

Back 65

Opioid Agonist

Front 66

These classes effect the production of prostaglandilins? Aspirin

Back 66

Nonopioid Analgesics

Front 67

Reverses the effects of opioid drugs? Narcan

Back 67

Opioid antagonist

Front 68

Medications are given with others drugs to enhance their effects? Diazepam

Back 68

Adjunct Medications

Front 69

Displays both agonistic and antagonistic properties? Nubain

Back 69

Opioid Agonist-Antagonist

Front 70

State of decreased anxiety and inhibitions?

Back 70

Sedation

Front 71

Instigation of sleep ?

Back 71

Hypnosis

Front 72

Drugs used to treat mental dysfunction?

Back 72

Psychotheraputic medication

Front 73

Common side effects of anti-psychotic meds? Muscle tremors

Back 73

Extrapyramidal symptoms

Front 74

Phenothiazines, Butyrophenones, Atypicals?

Back 74

Major classes of antipsychotics

Front 75

TCA's , SSRI's , MAOI's ?

Back 75

Major classes of antidepressants

Front 76

Nervous system that controls involuntary actions?

Back 76

Autonomic nervous systems

Front 77

Groups of autonomic nerve cells located outside the central nervous system?

Back 77

Autonomic ganglia

Front 78

Nerve fibers that extend from the central nervous system to the autonomic ganglia?

Back 78

Preganglionic nerves

Front 79

Nerves that extend from the autonomic ganglia to the target tissue?

Back 79

Postganglionic nerves

Front 80

Space between nerves?

Back 80

Synapse

Front 81

Specialized synapse between a nerve cell and an organ?

Back 81

Neuroeffector junction

Front 82

Chemical messenger that conducys a nervous impulse?

Back 82

Neurotransmitter

Front 83

Pertaining to the neurotransmitter ACH ?

Back 83

Cholinergic

Front 84

Pertaining to the neurotransmitter Norepi ?

Back 84

Adrenergic

Front 85

Drug that causes effects like those of parasympathetic nervous system?

Back 85

Parasympathomimetic

Front 86

Drug that blocks the action of the Parasympathetic nervous system?

Back 86

Parasympatholytic

Front 87

SLUDGE ?

Back 87

Salivation , Lacrimation , Urination , Defecation , Gastric Motility , EMesis

Front 88

Muscarinic , Nicotinic , Nicotinic N , Nicotinic M ?

Back 88

Types of parasympathetic ACH receptors

Front 89

Hot as Hell , Blind as a bat , Dry as a bone , Red as a beet , Mad as a hatter ?

Back 89

Effects of Atropine Overdose

Front 90

Blocks ACH only at Nicotinic sites ?

Back 90

Nicotinic Cholinergic Antagonists

Front 91

Blocks the effects of ACH at the Muscarinic receptors?

Back 91

Muscarinic Cholinergic Antagonist

Front 92

Drug that causes the effect like those of the Sympathetc Nervous system?

Back 92

Sympathomimetic

Front 93

Drug that blocks the action of the Sympathetic nervous system ?

Back 93

Sympatholytic

Front 94

Natural Catecholamines?

Back 94

Epi , norpi , dopamine

Front 95

Synthetic Catecholamines?

Back 95

Isoproterenol, dobutamine

Front 96

Drug userd to treat and prevent abnormal cardiac rhythm?

Back 96

Antidysrhythmic

Front 97

Constricts arteries and veins? Pupilary dialation?

Back 97

Alpha 1

Front 98

Inhibits NorEpi?

Back 98

Alpha 2

Front 99

Increase heart conductivity , Automicity , Contractivity, Renin Release?

Back 99

Beta 2

Front 100

Bronchodilation, dialates arterioles, inhibit uterine contrtaction, and Muscle tremors?

Back 100

Beta 2

Front 101

Drug that best demonstrates the class's common properties and its particular characteristics?

Back 101

Prototype

Front 102

Drug used to to treat and prevent abnormal cardiac rhytms?

Back 102

Antidysrhythmic

Front 103

Class 1 antidysrhythmic

Back 103

Sodium chanel blocker 1A, 2A , 3A

Front 104

Class 2 anti's

Back 104

Beta-Blockers

Front 105

Class 3 Anti's

Back 105

Potassium blocker

Front 106

Class 4 Anti's

Back 106

CA++ Channel blockers

Front 107

Drug's used to treat Hypertension?

Back 107

Antihypertensive

Front 108

Drug used to reduce blood volume by increasing the amount of urine?

Back 108

Diuretic

Front 109

Stable Angina , Unstable Angina , Prinzmetal's Angina ?

Back 109

3 Basic tpes of Pectoris Angina ( chest pain )

Front 110

The stoppage of bleeding ?

Back 110

Hemostasis

Front 111

Acts directly on thrombi to break them down ?

Back 111

Fibrinolytic

Front 112

Drug used to treat high cholesterol?

Back 112

Antihyperlipidemic

Front 113

CNS simulants that have additional bronchodilatory properties?

Back 113

Methlxanthines

Front 114

Mediator released from mast cells upon contact with allergies?

Back 114

Leukotrienes

Front 115

Substance that decreases surface tension?

Back 115

Surfactant

Front 116

Medication used to prevent vomitting?

Back 116

Antiemetic

Front 117

Drugs used to treat cancer?

Back 117

Antineoplastic

Front 118

Disease causing organism ?

Back 118

Pathogen

Front 119

The body's ability to respond to the presence of a pathogen?

Back 119

immunity

Front 120

Solutions containing whole antibodies for a specific pathogen?

Back 120

Serum