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12 Cards in this Set

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Cephalothin
(1st gen)
Cephalosporin of choice in treatment of severe staphylococcal infection (endocarditis).
Cefazolin
-1st generation
-Good against E. coli and Klebsiella.
-Only 1st gen. Ceph. still in use.
Cephalexin
(1st generation)
Less active against penicillinase-producing staph; acid stable.
Cefadroxil
(1st generation)
Oral preperation used for UTIs
Cefaclor
(2nd generation)
To treat sinusitis and otitis media
Cefuroxime
(2nd generation)
Crosses BBB - used for meningitis.
Cefoxitin
(2nd generation)
Used for mixed anaerobic infections such as peritonitis or diverticulitis.
Cefamadole
(2nd generation)
-Broader 2nd gen. cephlasporin; varied usage.
-Bleeding problems due to Vit K metabolism.
Cefotaxime
(3rd generation)
Better at G- bacilli, including many drug-resistant strains.
Cefoperazone
(3rd generation)
Affects Vit K function; Do not use.
Cefixime
(3rd Generation)
Oral preperation
Cefepime
(4th generation)
-excellent penetration into CSF.
-stable to many plasmid-encoded B-lactamases, but susceptible to extended-spectrum B-lactamases.