Pharmacology Cards_ Hypothalamic And Pituitary Drugs

Front 1

ACTH agonist and its use

Back 1

Cosyntropin
to dx: CAH and adrenal insufficiency- measure cortisol before and after this drug

Front 2

Somatram and Somatropin

Back 2

GH agonists w/ direct and indirect actions

Front 3

IGF-1 agonist

Back 3

Mecaserpin

Front 4

use of Mecaserpin

Back 4

Laron dwarfism and GH deficiency

Front 5

will dopamine like drugs increase or decrease GH secretion? What are they used for

Back 5

decrease release of GH just pretty much like Pegvisomant - used to tx acromegaly
they are bromocriptine and cabergolin

Front 6

ADH acts on what receptors

Back 6

V1- vasoconstriction
V2 - renal fluid reabsorption-> increase blood volume->increase arterial pressure

Front 7

FSH agonist

Back 7

Urofollitropin and Follitropin

Front 8

Pevisomant

Back 8

GH antagonist tx of acromegaly. Dopamine agonists like cabergoline and bromocriptine can be used in acromegaly.

Hint 8

tx of acromegaly

Front 9

tx of hyperprolactinima

Back 9

bromocriptine or cabergolin

Front 10

oxytocin antagonist

Back 10

Atosibam

Front 11

Menotrophin

Back 11

both FSH and LH agonist

Front 12

LH agonist

Back 12

hChorionic Gonadotropin
use in ovulation induction and male infertility

Front 13

Tx of SIADH

Back 13

Conivaptan-inhibits vasopressin receptor and used in SIADH.
Also other drugs used Lithium, Demeclocyline

Front 14

treatment of nephrogenic
diabetes insipidus

Back 14

Thiazides, Amiloride

Front 15

Octreotide

Back 15

somatostatin analog, which is 45 times more potent in inhibiting the GH secretion.
Used for acromegaly, refractory diarrhea (carcinoid syndrome and VIPoma), esophageal varices.
It is associated with nausea, vomiting, abdominal cramps and gall stones.

Front 16

Corticorelin

Back 16

this is CrH analog
indicated for differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.

Front 17

GnRH agonist

Back 17

Gonadorelin – short acting- to induce ovulation
Leuprolide, Nafarelin, Goserelin – long acting –tx endometriosis

Front 18

GnRH antagonist

Back 18

Ganirelix- NO AE, used in tx of precocious puberty, prostate and breast ca and in endometriosis

Front 19

Cosyntropin

Back 19

synthetic ACTH agonist

Front 20

TX of cental diabetes incipidus

Back 20

Desmopressin

Front 21

drug to tx premature labor

Back 21

Atosiban

Front 22

bromocriptin and caberolin

Back 22

tx of hyperprolactinoma, they are dopamine like drugs
it's also used in tx of acromegaly

Front 23

IGF 1- agonist

Back 23

Mecasermin

Front 24

Ganirelix

Back 24

GnRH antagonist- used in tx of precocious puberty and prostate and breast ca and endometriosis

Front 25

what is Ghrelin

Back 25

it's a GI hormone that induces release of GH

Front 26

used to prevent postpartum hemorrhage

Back 26

oxytocin

Front 27

GH antagonist

Back 27

pegvisomant

Front 28

used to tx nocturnal enuresis in kids

Back 28

desmopressin

Front 29

used to tx von Willenbrand disease

Back 29

desmopressin

Front 30

GHRH agonist

Back 30

sarmorelin

Front 31

CrH agonist

Back 31

corticorelin

Front 32

TrH agonist

Back 32

protirelin

Front 33

Leuprolide

Back 33

GnRH long lasting agonist

Front 34

gonadorelin

Back 34

GnRH short lasting agonist

Front 35

used to tx refractory diarrhea

Back 35

octreotide

Front 36

complication of this drug is carpal tunnel syndrome

Back 36

GH synthetic preparation

Front 37

cause wasting syndrome in AIDS pts

Back 37

GH synthetic hormone

Front 38

causes seizures and hyponitreamia

Back 38

nasal oxytosin if used for tx of milk letdown reflex