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23 Cards in this Set
- Front
- Back
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drug that interferes with growth process of microbe by substituting itself in place of an essential AA.
Give example |
competitive antagonist
Sulfonomide Drugs -Gantrisin -Bactrim -Septrin |
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Which drug(s) works by inhibition of cell wall synthesis
a) Sulfonomides b) Penicillins c) Cephalosporins d) Aminoglycosides |
penicillins
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which drug(s) acts by having a detergent like effect on the microbes cell membrane
a) tetracyclines b) cephalosporins c) aminoglycosides d) chrolaphenicol |
cephalosporins
similar to penicilin less resistant to staphlycoccla penicillinase broad spectrum higher level of renal damage |
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which drug(s) works by inhibiting essential protein synth
a) aminoglycosides b) sulfonimides c) cephalosporins d) penicillins |
aminoglycosides
gram +/-, tubercle bacillus very strong TOXIC- ototoxocity, nephrotoxicity streptomycin, kanamycin sulfonimides- competitive antag cephalosporins- action on cell membrane penicillins- inhibit cell wall synth |
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this drug inhibits nucleic acid synth, but tends to be bacteriostatic, and should not be taken with dairy products
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tetracyclines
wide spectrum, favorable therapeutic index |
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may cause gray teeth in children whose mothers took these during pregnancy
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tetracycline
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inhibits protein synth via 50s ribosomal subunit
a) chloramphenical b) Aminoglycosides c) microglides d) clindomycin |
microglides
erythromycin- sub for penicillin azithromycin- respiratory/skin infections chlarithromycin- respiratory/skin infections |
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strongest antimicrobial, restricted use for TB cases only
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vancomycin
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Which drug(s) has a host of incompatibilites and may interact with some chinese herbs
a) Carbapenems b) Ketolide c) Oxalidinone d) Quinolones |
Carbapenems
may cause seizure (also monobactam, lipopeptide) |
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used to treat septicemia
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monobactam
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used to treat complex skin infections such as burns, has many incompatibilities and may cause cardiac and renal failure, and diarrhea
a) lipopeptide b) ketolide c) carbapenems d) oxazolidinone |
lipopeptide
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This drug (s) is a synergistic combination but may exacerbate the effects of statin, anticonvulsant, and anti arrhythmic drugs
a) Metronidazole b) Ketolide c) Oxazolidine d) Streptogramin |
streptogramin- tx drug resistant ab/skin infections
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acts against DNA of protozoa, Anaerobic Bacteria, and Amoebae
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Metronidazole- can cause seizure, paresthesia, candida overgrowth
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may cause seizure, paresthesia, and candida overgrowth
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metronidazole
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True about Streptomycin
a) aminoglycoside b) Ototoxicity c) Nephrotoxicity d) reserved for TB |
All true
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T/F
antitubercular drugs are given as a combo over a 1 year span because it takes that long for the px to no longer be contagious |
F
px no longer contagious several days after starting tx |
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tubercular drug that may cause seizure and lupus like symptoms
a) streptomycin b) Rifampin c) Isonaizid d) Quinidine |
Isonaizid
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T/F
Rifampin can be an alternative to ethambutol |
true - for antitubercular
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May cause seratonin syndrom in px taking seratonergic drugs
a) Ketolide b) Streptogramin c) Oxazolidinone d) Lipopeptide |
Oxazolidinone-
tx drug resistant skin , respiratory, ab infections, Host of incompatibilities. works by preventing bacterial cell protein synth |
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CI in px with growing bones, and history of seizures
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quinolones
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prevents DNA replication for most gram (-) bactia and has a wide spectrum of action except is not useful for treating infections of the nervous system
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quinolones
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may cause toxicity of used with other Statin drugs or Anticonvulsants
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Ketolide
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Which is not considered a Microglide
a) Azithromycin b) Clarithromycin c) Erythromycin d) Vancomycin |
Vancomycin- last resort for staph infections - may cause oto/nephrotoxicity, hypersensitivity Red Man Syndrome
(Streptomycin= aminoglycoside reserved for TB) |
