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22 Cards in this Set
- Front
- Back
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Class IA:
What does it do? Adverse effects? |
Slows phase 0 depolarization.
Prolongs action potential. Slows conductance. May aggravate pre-existing arrhythmias. Dizziness, headache, blurred vision. |
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Qunidine?
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Class IA anti-arrhythmic.
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Procainamide?
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Class IA anti-arrhythmic.
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Disopyramide?
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Class IA anti-arrhythmic.
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Class IB:
What does it do? Adverse effects? |
Shortens phase 3 repolarization.
Decreases duration of action potential. May aggravate pre-existing arrhythmias. Agitation, convulsions (if it gets into CNS). Drowsiness, slurred speech. |
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Lidocaine?
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Class IB anti-arrhythmic.
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Mexiletine?
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Class IB anti-arrhythmic.
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Tocainide?
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Class IB anti-arrhythmic.
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Flecainide?
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Class IC anti-arrhythmic.
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Propafenone?
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Class IC anti-arrhythmic.
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Class IC anti-arrhythmic:
What does it do? Adverse effects? |
Block resting sodium channels instead of open channels.
Slows phase 0 depolarization. May aggravate pre-existing arrhythmias and CHF. Contraindicated with CHF. Dizziness, headache, blurred vision (in CNS). May induce ventricular tachycardia. |
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Class II: beta blockers
What do they do? |
Slows phase 4 depolarization.
Prolongs AV conductance. Decreases heart rate and contractility. |
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Pindolol?
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Beta-blocker.
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Metoprolol?
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Beta-blocker.
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Propranolol?
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Beta-blocker.
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Class III: K+ channel blocker:
What do they do? |
Prolong phase 3 repolarization.
Used to treat ventricular tachycardia. Not great (non-specific)--class II and class I effects as well. Find something else first. |
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Sotalol?
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K+ channel blocker.
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Verapamil?
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Calcium channel blocker.
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Diltiazem?
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Calcium channel blocker.
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Class IV: Calcium channel blockers:
What do they do? Adverse effects? |
Decrease phase 4 spontaneous depolarization.
Particularly in AV node. Prolong the effective refractory period. Gingival enlargement. Potentiate opioid analgesia. |
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Digoxin:
What does it do? |
Shortens refractory period in myocardial cells but not in nervous tissue.
Prolongs effective refractory period. Diminishes conduction velocity in Purkinje fibers. Not good for arrhythmias. |
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Name two beta agonists.
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1. Isoproterenol
2. Epinephrine |
