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14 Cards in this Set

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Prednisone is an intermediate acting?
corticosteroid (glucocorticoid)
Brands of prednisone are?
Orasone
Meticorten
Deltasone
Cordrol
Sterapred
Prednisone is the preferred oral glucocorticoid for?
antiinflammation
immunosuppression
Define corticosteroids?

mineralcorticoids
glucocoricoids
gonadocorticoids
androgens
testosterone
well over two dozen STEROID hormones which are synthesized from cholesterol by the adrenal cortex...some examples of corticosteroids are?
What is a glucocorticoid?
an adrenal agents and one of the more than two different dozen corticosteroids found in the adrenal cortex; these metabolic cells are found in zona fasiculata...helps depress antiinflammatory and immune response...ACTH is the major stimulus for glucocoricoid release
What is prednisone used for?
systemically and locally in a wide variety of chronic diseases including?
inflammatory
allergic
asthma
autoimmune disorders
MOA of prednisone?
suppresses what?
inflammation
normal immune response
suppress adrenal function at
chronic doses
Therapeutic effects of prednisone?
suppression of normal immune
response
replacement therapy in
adrenal insufficiency
okay
In the liver, prednisone is converted by the liver to?
prednisolone which is then metabolized by the liver
Adverse reactions with prednisone?
thromboembolism
peptic ulceration
Assess patient for signs of?

hypotension
weight loss
weakness
nausea
vomiting
anorexia
lethargy
confusion
restlessness
adrenal insufficiency before and during therapy

signs of adrenal
insufficiency include?
What else does nurse assess for?
monitor intake and output ratios and daily weights
What is nurse observing for?
peripheral edema
steady weight gain
rales/crackles
dyspnea
What are cerebral edema issues that should be monitored?
assess for LOC and headache during therapy