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105 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Common feature of Sulfonamides: |
SULFA |
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Sulfonamides Mechanism of Action: |
Prevents Folic Acid Synthesis |
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Indication of Sulfonamides: |
UTIs OM "travelers diarrhea" |
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Examples/Meds with Sulfonamides: |
Bactrim Septra |
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Sulfonamides DD: |
Sulfonylureas (increase BS) Warfarin (increase bleeding) |
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Sulfonamides AE: |
Photosensivity |
😎 |
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NI of Sulfonamides: |
co-allergens (thiazides, sulfonylureas) |
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PE of Sulfonamides: |
Increase water intake (3-4 L) daily |
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Common feature for Penicillin: |
icillin |
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Penicillin Mechanism of Action: |
Inhibits cell wall synthesis |
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Indications for Penicillin: |
WIDE SPECTRUM |
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Examples/Meds with Penicillin: |
Penicillin G Amoxicillin Ampicillin Zosyn Augmentin Unasyn |
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Penicillin SE: |
urticaria, pruritis, angiodema |
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Penicillin AE: |
Anaphylaxis |
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Penicillin DD: |
OC's anticoagulants (increase bleeding) |
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NI for Penicillin: |
know s/s for anaphylaxis IV: give 1 hr before other antibiotic |
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PE for Penicillin: |
PO - 1 hr before or 2 hrs after meal Take with full glass of water Oral Suspension - Refrigerate |
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Cephalosporins Common Feature: |
CEF CEPHA |
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Cephalosporins Mechanism of Action: |
Inhibits cell wall synthesis |
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Indication of Cephalosporins: |
Surgical prophylaxis (1st gen.) Gonorrhea, PID (3rd gen.) Tx: MRSA (5th gen.) |
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Examples/Meds with Cephalosporins: |
1st - Cephazolin 3rd - Ceftriaxone 4th - Cefepime 5th - Ceftaroline |
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Cephalosporins SE: |
diarrhea, abd cramps, rash, itching, edema. |
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Cephalosporins DF and DD: |
Alcohol intolerance Warfarin (increased bleeding) |
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Cephalosporins PE: |
No alcohol for 3 days eat yogurt to avoid superinfections |
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Carbopenems Common feature: |
-PENEMS |
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Carbopenems Mechanism of Action: |
Inhibits cell wall synthesis |
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Indications of Carbopenems: |
MDR Complicates body and tissue infection Meningitis Pyelonephritis |
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Examples/Meds with Carbopenems: |
Meropenem Ertapenem Impipenem-cilastatin Doripenem |
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Carbopenems AE: |
Seizures respiratory distress death |
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Carbopenems SE: |
N/V D Rashes |
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NI for Carbopenems: |
IM - reconstitute with 1% Lidocaine IV - infuse over 40 - 60 minutes |
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Monobactams Common feature: |
ONAM |
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Monobactams Mechanism of Action: |
Inhibits cell wall sysnthesis |
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Indication of Monobactams: |
WIDE RANGE UTI SEPTICEMIA ABD and GU infection |
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Examples/Meds with Monobactams: |
Aztreonam |
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Monobactams SE: |
N/V D rash |
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Monobactams AE: |
EKG changes Elevated LFT's |
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Tetracyclines Common feature: |
CYCLINE |
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Tetracycline Mechanism of Action: |
Inhibits protein sysnthesis |
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Tetracycline Indicators: |
WIDE SPECTRUM Gonorrhea/Chlamydia RMSF Acne |
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Example/Meds with Tetracyclines: |
Tetracyclines Doxycycline |
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Tetracycline AE: |
Discoloration of teeth Photosensitivity |
😎 |
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Tetracycline C: |
Pregnant women Breastfeeding Children < 8 |
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Tetracycline DD: |
OC's (< effect) |
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NI of Tetracycline: |
Binds with Ca+, Mg, Al |
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PE for Tetracycline: |
No milk, antacid, iron preps within 1 hr before or 2 hrs after |
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Aminoglycosides Common feature: |
CIN |
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Aminoglycosides Mechanism of Action: |
Prevents protein sysnthesis |
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Aminoglycosides Indications: |
E. Coli Klebsiella spp Prophylaxis: GU and GI procedures to prevent endocarditis |
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Examples/Meds with Aminoglycosides: |
Gentamycin Tobramycin Neomycin |
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Aminoglycosides AE: |
Ototoxic Nephrotoxic Thrombocytopenia Agranulocytes |
👂🏽 |
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Aminoglycosides DD: |
Wafarin (do not use) NMBDs (do not use) Loop diuretics (ototoxicity) |
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Aminoglycosides NI: |
Monitor blood levels (BUN & Crea) Hydration (renal function) IM - ice site to reduce pain IV - infuse slowly over 30-60 min |
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Fluoroquinolones Common feature: |
FLOXACIN |
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Fluoroquinolones Mechanism of Action: |
Alters DNA |
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Fluoroquinolones Indications: |
UTI URI Pneumonia Gonorrhea Anthrax (cipro) |
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Examples/Meds with Fluoroquinolones: |
Ciproflaxin Levoflaxin |
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Fluoroquinolones AE: |
Photosensitivity |
😎 |
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Fluoroquinolones PE: |
do not take with acidic foods or antacids Take 2 hrs before or after meals Drink plenty of fluids (crystalluria) |
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Fluoroquinolones W: |
Monitor for CNS effects (driving) |
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Macrolides (z-pack) Common feature: |
ROMYCIN |
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Macrolides Mechanism of Action: |
Prevents protein sysnthesis |
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Macrolides Indications: |
Strep URI LRI Pneumonia |
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Example/Meds with Macrolides: |
Erythromycin Azithromycin |
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Macrolides DD: |
Theophylline (toxicity) |
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Macrolides AE: |
Eosinophilla Anaphylaxis Hepatotoxic |
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Macrolides PE: |
Full of water 1 hr before or 2 hrs after meals Coated can be taken wit meals NO FRUIT JUICE (Acid-sensitive) |
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Macrolides NI: |
Monitor LFT's |
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Cleocin Indications: |
Chronic bone Infection Abd infections GU infections |
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Examples/Meds with Cleocin: |
Clindomycin |
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Cleocin AE: |
C. diff |
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Oxazolidinones Brand Name: |
Zyvox |
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Oxazolidinones Indications: |
VRE MRSA |
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Examples/Meds with Oxazolidinones: |
Linezolid |
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Oxazolidinones AE: |
Hypotension |
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Oxazolidinones DD: |
SSRI (serotonin syndrome) |
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Oxazolidinones DF: |
Tyramines |
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Flagyl Indications: |
Protozoal Abd infections GYN infections |
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Examples/Meds with Flagyl: |
Metronidazole |
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Macrodantin Indications: |
UTI |
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Examples/Meds with Macrodantin: |
Nitrofurantoin |
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Synercid Indications: |
VRE MRSA |
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Examples/Meds with Synercid: |
quinupristin-dalfopristin |
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Synercid AE: |
Myalgia (muscle pain) Arthralgia (joint pain) |
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Macrodantin W: |
Fetal hepatotoxicity |
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Macrodantin CA: |
monitor renal function |
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Vancocin Indications: |
MRSA (DOC) C. diff |
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Examples/Meds with Vancocin: |
Vancomycin |
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Vancocin AE: |
ototoxicity Nephrotoxicity RED MAN SYNDROME |
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Vancocin DD: |
NMBDs (additive effect) |
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Vancocin NI: |
monitor blood level IV: infuse over 60 min |
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Lipopeptides Brand Name: |
Cubicin |
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Lipopeptides Indications: |
MRSA VRE |
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Examples/Meds with Cubicin: |
Daptomycin |
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Vibativ Indications: |
MRSA VRE |
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Examples/Meds with Vibativ: |
Telavancin |
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Vibativ AE: |
Renal Toxicity QT prolongation |
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Dalvance Indications: |
MRSA |
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Examples/Meds with Dalvance: |
Dalbavancin |
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Dalvance NI: |
Long 1/2 life (dosed once a week) |
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Polypeptide Brand Name: |
Coly-Mycin |
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Polypeptide Indications: |
Gram-negative |
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Examples/Meds with Coly-Mycin: |
Colistimethate |
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Polypeptide AE: |
Acute respiratory failure |
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Polypeptide NI: |
Commonly called Colistin |
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