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10 Cards in this Set
- Front
- Back
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Actions of warfarin are potentiated by... |
Aspirin Sulphonamides NSAIDs |
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Actions of warfarin are decreased by... |
Barbiturates Vitamin K Colestipol |
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Side effects of Warfarin |
Teratogenic (therefore contraindicated in birth) Haemorrhage |
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Limitations of Heparin |
Platelet factor 4 inhibits heparin If Xa is already bound to fibrin it can't interact with Hep/ATIII |
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Side effects of Heparin |
Haemorrage Thrombosis (rare) Occasional osteoporosis Hypersensitivity Hypoaldosteronism |
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Heparin |
Heparin Calciparine Minihep Monoparin |
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LMW Heparin |
Certoparin Dalteparin Enoxaparin |
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Anti-thrombin III Independent |
Hirudin Hirugen Bivalirudin |
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Clinical use of heparin |
Short term for... Prevention of deep vein thrombosis Treatment of deep vein thrombosis Prevention of pulmonary emboli Prevention of thrombosis on prosthetic heart valve |
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Clinical use of warfarin |
Prolonged therapy for... Prevention of deep vein thrombosis Treatment of deep vein thrombosis Prevention of pulmonary emboli Prevention of thrombosis on prosthetic heart valve |
