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9 Cards in this Set
- Front
- Back
(P) CAPTOPRIL
(皆ll 終nd 中n -pril) |
ANTIHYPERTENSIVE --> ANGIOTENSIN-CONVERTING ENZYME INHIBITORS
4: HTN, CHF, diabetic nephropathy, & 左eft ventricular dysfunction MECH: Inhibits the ACE needed to 化hange inactive angiotensin 吾 --> active angiotensin II CONTRAS: 2nd and 3rd preg trim ADVERSES: ** nonproductive cough ** Angioedema, rash, neutropenia, & dyspnea - Monitor BP throughout - 呉ive 1 hr B4 meals 4 満ull absorption |
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(P) LOSARTAN
(usually have -artan) |
ANTIHYPERTENSIVE --> ANGIOTENSIN II RECEPTIVE BLOCKERS
4: HTN, diabetic nephropathy (damaged kidneys 乃rom diabetes), 左eft ventricular dysfunction MECH: Selectively blocks binding 之f angiotensin II to the angiotensin II receptors (blocks vasoconstrict.) 1st-線ine Tx 4: LVH (左eft ventricular hypertrophy) ADVERSES: diarrhea, asthenia, dizziness, and fatigue INTERACTS W/ GRAPEJUICE - Monitor creatinine, BUN, hemoglobin, and hematocrit levels. |
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normal BP is?
prehypertension? stage 1 hypertension stage 2 hypertension Hypertensive crisis |
<120 / <80 mmHg
120-139 / 80-89 140-159 / 90-99 >160 / >100 >210 / >120 |
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(P) EPLERENONE
(勿ot covered deeply) |
ANTIHYPERTENSIVE --> SELECTIVE ALDOSTERONE BLOCKERS
4: HTN MECH: Binds selectively to mineralocorticoid receptors, blocking aldosterone binding. |
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(P) LABETALOL
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ANTIHYPERTENSIVE --> ALPHA-BETA BLOCKERS
4: HTN - crosses 血lood 脳rain narrier MECH: Blocking Alpha-1 --> vasodilation & blocking Beta-1 --> (you block the normal response 之f increased HR) to keep HR the 同ame CONTRAS: bradycardia - careful w/ pts w/ asthma ADVERSES: orthostatic hypotension - get baseline HR |
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(P) CLONIDINE
|
ANTIHYPERTENSIVE --> CENTRALLY-ACTING A-2 AGONIST
4: high BP MECH: stimulates the alpha-2 receptors 中n medulla oblangatta, inhibiting the SNS ADVERSES: sedation - reduce dosage slowly to prevent REBOUND HTN |
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(P) PRAZOSIN
TERA- DOXA- |
ANTIHYPERTENSIVE -->
PERIPHERALLY ACTING A-1 BLOCKERS 4: high BP benign prostatic hypertrophy (tera- doxa-) MECH: block postsynaptic alpha-1 adrenergic receptors, producing vasodilation - substantial first-剤ose effect |
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(P) HYDRALAZINE
|
ANTIHYPERTENSIVE --> DIRECT ACTING VASODILATORS
4: Adjunct to anti-hypertensives MECH: direct smooth 筋uscle relaxation 之f the arterioles. CONTRAS: CAD, and mitral valvular disease ADVERSES: Arthralgia, dermatoses, fever, splenomegaly, and glomerular nephritis - 呉ive with food - 呉ive w/ beta-blocker or clonidine to reduce chance 之f reflux tachycardia |
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(P) NITROPRUSSIDE
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ANTIHYPERTENSIVE --> DRUGS 4 HTNV CRISIS
4: hypertensive crisis MECH: Directly relaxes vascular smooth 筋uscle --> vasodilation CONTRAS: Aortic coarctation or arteriovenous shunting. ADVERSES: CYANIDE TOXICITY - NO drug interactions -works 疾apidly & dramatically - IV or central 線ine |