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110 Cards in this Set

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What drug group(s) inhibit cell wall synthesis?
* Beta Lactams
* Glycopeptides (Vancomycin)

“Barrier Lysing Guys”
What drug group(s) inhibit protein synthesis?
* Aminoglycosides (30S)
* Tetracyclines (30S)
* Macrolides (50S)
* Lincosamides (50S)
* Phenicols (50S)

“The Large Protein Mashing Agents”
What drug group(s) inhibit folic acid synthesis?
Sulfonamides
What drug group(s) inhibit DNA gyrase/topoisomerase?
Fluoroquinolones
What drug group(s) disrupt DNA/RNA sythesis?
* Metronidazole
* Rifampin
(The others-that dont have a category)

“Restrict Multiplication”
What drug group(s) are nephrotoxic?
* Sulfonamides
* Tetracyclines
* Aminoglycosides

“So These Are nephrotoxic”
What drug group(s) are hepatotoxic?
* Tetracycline
* Macrolides
* Metronidazole
“These Might Mediate hepatotoxicity”
What drug group(s) cause GI effects?
* Tetracycline
* Macrolides
* Metronidazole
* Rifampin

“These Might Mediate Rumbly tummies”
What drug group(s) are known to cause allergic reactions?
Beta Lactams

“Bring Lots of allergies”
What drug group(s) are known to cause CNS effects?
* Fluoroquinolones
* Metronidazole

“Found to Mediate CNS”
What drugs are Fluoroquinolones?

HInt: MEDCO
1. Marbofloxacin
2. Enrofloxacin
3. Difloxacin
4. Ciprofloxacin
5. Orbifloxacin
What drugs are Aminoglycosides?

HInt: TANG
1.Tobramycin
2. Amikacin
3. Neomycin
4. Gentamicin
What drugs are Macrolides?

HInt: TEATT
1.Tylosin
2.Erythromycin
3.Azithromycin
4.Tulathromycin
5. Tilmicosin
What drugs are Lincosamides?

HInt: Corpus Luteum
1. Clindamycin
2. Lincomycin
What drug groups are the broad spectrum choices?
HINT: “The Broad Spectrum Choices”
*Tetracyclines
* Beta lactams
* Sulfonamides
* Chloramphenicol


“The Broad Spectrum Choices”
Does Metronidazole work on aerobic or anaerobic microbes?
anaerobic only
Do Fluorquinolones work on aerobic or anaerobic microbes?
aerobic only
What type of microbes are Aminoglycosides effective against?
Gram negative aerobes only
What drug groups are effective against Mycoplasma?
* Tetracyclines
* Macrolides
* Fluroquinolones

“mycoplasma are Tough Mother F***ers”
What is the main difference between the generations of Cephalosporins?
* First generation – best Gram (+) spectrum

* Second generation – medium of both

* Third generation – best Gram (-) spectrum
Drug group:Ciprofloxacin
MOA
Fluoroquinolones

Inhibit DNA gyrase/topoisomerase
Drug group:Amikacin
MOA
Aminoglycosides

Inhibit protein synthesis
Drug group:Clindamycin
MOA
Lincosamides

Inhibit protein synthesis
Drug group:Azithromycin
MOA
Macrolides

Inhibit protein synthesis
Drug group:Lincomycin
MOA
Lincosamides

Inhibit protein synthesis
Drug group:Erythromycin
MOA
Macrolides

Inhibit protein synthesis
Drug group:Difloxacin
MOA
Fluoroquinolones

Inhibit DNA gyrase/topoisomerase
Drug group:Gentamicin
MOA
Aminoglycosides

Inhibit protein synthesis
Drug group:Tilmicosin
MOA
Macrolides

Inhibit protein synthesis
Drug group:Tulathromycin
MOA
Macrolides

Inhibit protein synthesis
Drug group: Enrofloxacin
MOA
Fluoroquinolones

Inhibit DNA gyrase/topoisomerase
Drug group: Neomycin
MOA
Aminoglycosides

Inhibit protein synthesis
Drug group:Tylosin
MOA
Macrolides


Inhibit protein synthesis
Drug group:Tobramycin
MOA
Aminoglycosides

Inhibit protein synthesis
Drug group: Marbofloxacin
MOA
Fluoroquinolones

Inhibit DNA gyrase/topoisomerase
Drug group:Orbifloxacin
MOA
Fluoroquinolones

Inhibit DNA gyrase/topoisomerase
What is MIC?
– concentration of drug required to inhibit growth of bacteria
What is MBC?
concentration of drug required to kill bacteria
What is the breakpoint of an antimicrobial?
threshold between susceptible and resistant; different for each drug and organism
7 Aminoglycosides and Aminocyclitols
1. Amikacin
2. Dihydrostrptomycin
3. Gentamicin
4. Neomycin
5. Streptomycin
6. Apramycin
7. Spectinomycin
What drug group do the penicillins fall under?
Beta-lactams
5 categories of penicillins
1. Penicillins
2. Aminopenicillins
3. Penicillinase-Resistant Penicillin
4. Antipseudomonal Penicillin (Carboxypenicillins and Ureidopenicillins)
5. Beta-Lactamase Resistant Penicillin
2 Penicillin drugs
Penicillin G
Penicillin B
3 Aminopenicillins
1. Amoxicillin ( +/- clavulanate)
2. Ampicillin
3. Hetacillin
5 Penicillinase-Resistant Penicillin drugs
1. Oxacillin
2. Methicillin
3. Cloxacillin
4. Dicloxacillin
5. Nafcillin
3 Antipseudomonal Penicillin (Carboxypenicillins and Ureidopenicillins) Drugs
1. Carbenicillin
2. Piperacillin
3. Ticarcillin
The only Beta-Lactamase Resistant Penicillin drug discussed
Temocillin
5 first generation Cephalosporins drugs? Are they oral or parenteral drugs?
1. Cephalothin (Parenteral)
2. Cefazolin (Parenteral)
3. Cephapirin (Parenteral)
4. Cefadroxil (Oral)
5. Cephalexin (Oral)
3 second generation Cephalosporin drugs
1. Cefotetan
2. Cefoxitin
3. Cefuroxime
8 third generation Cephalosporin drugs? Are they oral or parenteral drugs?
1. Cefotaxime (Parenteral)
2. Ceftizoxime (Parenteral)
3. Ceftriaxone (Parenteral)
4. Ceftiofur (Parenteral)
5. Cefovecin (Parenteral)
6. Cefixime (Oral)
7. Cefpodoxime (Oral)
8. Ceftazidime (Parenteral)
2 fourth generation Cephalosporin drugs
1. Cefepime
2. Cefquinome
Diaminopyrimidine drug
Trimethoprim
2 Phenicols
1. Chloramphenicol
2. Florfenicol
6 Fluoroquinolones
1. Ciprofloxacin
2. Danofloxacin
3. Difloxacin
4. Enrofloxacin
5. Marbofloxacin
6. Orbifloxacin
3 Lincosamides
1. Lincomycin
2. Clindamycin
3. Pirlimycin
6 Macrolides
1. Azithromycin
2. Clarithromycin
3. Erythromycin
4. Tilmicosin
5. Tulathromycin
6. Tylosin
7 Sulfonamides
1. Sulfachlorpyridazine
2. Sulfadimethoxine
3. Sulfamerazine
4. Sulfamethazine
5. Sulfanilamide
6. Sulfaquinoxaline
7. Sulfathiazole
Drug type: Enrofloxacin
Fluoroquinolone
Drug type: Lincomycin
Lincosamide
Drug type: Clarithromycin
Macrolide
Drug type: Chloramphenicol
Phenicol
Drug type: Azithromycin
Macrolide
Drug type:Trimethoprim
Diaminopyrimidine
Drug type:Sulfamerazine
Sulfonamide
Drug type: Tylosin
Macrolide
Drug Type: Cephalothin
1st Generation (Parenteral)Cephalosporin
Drug Type: Ceftriaxone
3rd Generation (Parenteral)Cephalosporin
Drug Type: Florfenicol
Phenicol
Drug Type: Danofloxacin
Fluoroquinolone
Drug Type: Clarithromycin
Macrolide
Drug type: Cefazolin
1st Generation (Parenteral)Cephalosporin
Drug type: Cefadroxil
1st Generation (Oral)Cephalosporin
Drug type: Cefotetan
2nd Generation Cephalosporin
Drug type: Ceftizoxime
3rd Generation (Parenteral)Cephalosporin
Drug type: Ceftriaxone
3rd Generation (Parenteral)Cephalosporin
Drug type: Cefepime
4th Generation Cephalosporin
Drug type: Cefquinome
4th Generation Cephalosporin
Drug type: Ceftazidime
3rd Generation (Parenteral)Cephalosporin
Drug type:Cephapirin
1st Generation (Parenteral)Cephalosporin
Drug type: Cephalexin
1st Generation (oral)Cephalosporin
Drug type: Cefadroxil
1st Generation (oral)Cephalosporin
Drug type:Cefpodoxime
3rd Generation (oral)Cephalosporin
Drug type:Cefixime
3rd Generation (oral)Cephalosporin
Drug type: Cefovecin
3rd Generation (Parenteral)Cephalosporin
Drug type: Cefuroxime
2nd Generation Cephalosporin
Drug type: Amoxicillin
Beta-lactam-Penicillin- Aminopenicillin
Drug type: Oxacillin
Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin
Drug type: Carbenicillin
Beta-lactam-Penicillin-
Antipseudomonal Penicillin
Drug type: Temocillin
Beta-lactam-Penicillin-
Beta-Lactamase Resistant Penicillin
Drug type: Piperacillin
Beta-lactam-Penicillin-
Antipseudomonal Penicillin
Drug type: Methicillin
Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin
Drug type: Ampicillin
Beta-lactam-Penicillin-
Aminopenicillin
Drug type: Hetacillin
Beta-lactam-Penicillin-
Aminopenicillin
Drug type: Cloxacillin
Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin
Drug type: Ticarcillin
Beta-lactam-Penicillin-
Antipseudomonal Penicillin
Drug type: Dicloxacillin
Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin
Drug type: Nafcillin
Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin
6 Potentiated Sulfonamides
1. Ormetoprim and Sulfadimethoxine
2. Pyrimethamine and Sulfadiazine
3. Pyrimethamine and Sulfaquinoxaline
4. Sulfadiazine and Trimethoprim
5. Sulfadoxine and Trimethoprim
6. Sulfamethoxazole and Trimethoprim
4 Tetracyclines
1. Chlortetracycline
2. Doxycycline
3. Oxytetracycline
4. Tetracycline
3 Miscillaneous Antibiotics
1. Metronidazole
2. Rifampin
3. Spectinomycin
Drug type: Spectinomycin
Miscillaneous Antibiotic
Drug type: Vancomycin
Glycopeptide
Drug type: Oxytetracycline
Tetracycline
Drug type: Sulfamethoxazole and Trimethoprim
Potentiated Sulfonamide
Drug type: Sulfathiazole
Sulfonamide
Drug type: Tulathromycin
Macrolide
Drug type: Rifampin
Miscillaneous Antibiotic
Drug type: Metronidazole
Miscillaneous Antibiotic
Drug type: Doxycycline
Tetracycline
Drug type: Chlortetracycline
Tetracycline