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110 Cards in this Set
- Front
- Back
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What drug group(s) inhibit cell wall synthesis?
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* Beta Lactams
* Glycopeptides (Vancomycin) “Barrier Lysing Guys” |
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What drug group(s) inhibit protein synthesis?
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* Aminoglycosides (30S)
* Tetracyclines (30S) * Macrolides (50S) * Lincosamides (50S) * Phenicols (50S) “The Large Protein Mashing Agents” |
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What drug group(s) inhibit folic acid synthesis?
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Sulfonamides
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What drug group(s) inhibit DNA gyrase/topoisomerase?
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Fluoroquinolones
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What drug group(s) disrupt DNA/RNA sythesis?
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* Metronidazole
* Rifampin (The others-that dont have a category) “Restrict Multiplication” |
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What drug group(s) are nephrotoxic?
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* Sulfonamides
* Tetracyclines * Aminoglycosides “So These Are nephrotoxic” |
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What drug group(s) are hepatotoxic?
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* Tetracycline
* Macrolides * Metronidazole “These Might Mediate hepatotoxicity” |
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What drug group(s) cause GI effects?
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* Tetracycline
* Macrolides * Metronidazole * Rifampin “These Might Mediate Rumbly tummies” |
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What drug group(s) are known to cause allergic reactions?
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Beta Lactams
“Bring Lots of allergies” |
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What drug group(s) are known to cause CNS effects?
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* Fluoroquinolones
* Metronidazole “Found to Mediate CNS” |
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What drugs are Fluoroquinolones?
HInt: MEDCO |
1. Marbofloxacin
2. Enrofloxacin 3. Difloxacin 4. Ciprofloxacin 5. Orbifloxacin |
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What drugs are Aminoglycosides?
HInt: TANG |
1.Tobramycin
2. Amikacin 3. Neomycin 4. Gentamicin |
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What drugs are Macrolides?
HInt: TEATT |
1.Tylosin
2.Erythromycin 3.Azithromycin 4.Tulathromycin 5. Tilmicosin |
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What drugs are Lincosamides?
HInt: Corpus Luteum |
1. Clindamycin
2. Lincomycin |
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What drug groups are the broad spectrum choices?
HINT: “The Broad Spectrum Choices” |
*Tetracyclines
* Beta lactams * Sulfonamides * Chloramphenicol “The Broad Spectrum Choices” |
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Does Metronidazole work on aerobic or anaerobic microbes?
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anaerobic only
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Do Fluorquinolones work on aerobic or anaerobic microbes?
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aerobic only
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What type of microbes are Aminoglycosides effective against?
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Gram negative aerobes only
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What drug groups are effective against Mycoplasma?
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* Tetracyclines
* Macrolides * Fluroquinolones “mycoplasma are Tough Mother F***ers” |
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What is the main difference between the generations of Cephalosporins?
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* First generation – best Gram (+) spectrum
* Second generation – medium of both * Third generation – best Gram (-) spectrum |
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Drug group:Ciprofloxacin
MOA |
Fluoroquinolones
Inhibit DNA gyrase/topoisomerase |
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Drug group:Amikacin
MOA |
Aminoglycosides
Inhibit protein synthesis |
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Drug group:Clindamycin
MOA |
Lincosamides
Inhibit protein synthesis |
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Drug group:Azithromycin
MOA |
Macrolides
Inhibit protein synthesis |
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Drug group:Lincomycin
MOA |
Lincosamides
Inhibit protein synthesis |
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Drug group:Erythromycin
MOA |
Macrolides
Inhibit protein synthesis |
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Drug group:Difloxacin
MOA |
Fluoroquinolones
Inhibit DNA gyrase/topoisomerase |
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Drug group:Gentamicin
MOA |
Aminoglycosides
Inhibit protein synthesis |
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Drug group:Tilmicosin
MOA |
Macrolides
Inhibit protein synthesis |
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Drug group:Tulathromycin
MOA |
Macrolides
Inhibit protein synthesis |
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Drug group: Enrofloxacin
MOA |
Fluoroquinolones
Inhibit DNA gyrase/topoisomerase |
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Drug group: Neomycin
MOA |
Aminoglycosides
Inhibit protein synthesis |
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Drug group:Tylosin
MOA |
Macrolides
Inhibit protein synthesis |
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Drug group:Tobramycin
MOA |
Aminoglycosides
Inhibit protein synthesis |
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Drug group: Marbofloxacin
MOA |
Fluoroquinolones
Inhibit DNA gyrase/topoisomerase |
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Drug group:Orbifloxacin
MOA |
Fluoroquinolones
Inhibit DNA gyrase/topoisomerase |
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What is MIC?
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– concentration of drug required to inhibit growth of bacteria
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What is MBC?
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concentration of drug required to kill bacteria
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What is the breakpoint of an antimicrobial?
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threshold between susceptible and resistant; different for each drug and organism
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7 Aminoglycosides and Aminocyclitols
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1. Amikacin
2. Dihydrostrptomycin 3. Gentamicin 4. Neomycin 5. Streptomycin 6. Apramycin 7. Spectinomycin |
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What drug group do the penicillins fall under?
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Beta-lactams
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5 categories of penicillins
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1. Penicillins
2. Aminopenicillins 3. Penicillinase-Resistant Penicillin 4. Antipseudomonal Penicillin (Carboxypenicillins and Ureidopenicillins) 5. Beta-Lactamase Resistant Penicillin |
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2 Penicillin drugs
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Penicillin G
Penicillin B |
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3 Aminopenicillins
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1. Amoxicillin ( +/- clavulanate)
2. Ampicillin 3. Hetacillin |
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5 Penicillinase-Resistant Penicillin drugs
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1. Oxacillin
2. Methicillin 3. Cloxacillin 4. Dicloxacillin 5. Nafcillin |
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3 Antipseudomonal Penicillin (Carboxypenicillins and Ureidopenicillins) Drugs
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1. Carbenicillin
2. Piperacillin 3. Ticarcillin |
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The only Beta-Lactamase Resistant Penicillin drug discussed
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Temocillin
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5 first generation Cephalosporins drugs? Are they oral or parenteral drugs?
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1. Cephalothin (Parenteral)
2. Cefazolin (Parenteral) 3. Cephapirin (Parenteral) 4. Cefadroxil (Oral) 5. Cephalexin (Oral) |
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3 second generation Cephalosporin drugs
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1. Cefotetan
2. Cefoxitin 3. Cefuroxime |
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8 third generation Cephalosporin drugs? Are they oral or parenteral drugs?
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1. Cefotaxime (Parenteral)
2. Ceftizoxime (Parenteral) 3. Ceftriaxone (Parenteral) 4. Ceftiofur (Parenteral) 5. Cefovecin (Parenteral) 6. Cefixime (Oral) 7. Cefpodoxime (Oral) 8. Ceftazidime (Parenteral) |
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2 fourth generation Cephalosporin drugs
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1. Cefepime
2. Cefquinome |
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Diaminopyrimidine drug
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Trimethoprim
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2 Phenicols
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1. Chloramphenicol
2. Florfenicol |
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6 Fluoroquinolones
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1. Ciprofloxacin
2. Danofloxacin 3. Difloxacin 4. Enrofloxacin 5. Marbofloxacin 6. Orbifloxacin |
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3 Lincosamides
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1. Lincomycin
2. Clindamycin 3. Pirlimycin |
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6 Macrolides
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1. Azithromycin
2. Clarithromycin 3. Erythromycin 4. Tilmicosin 5. Tulathromycin 6. Tylosin |
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7 Sulfonamides
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1. Sulfachlorpyridazine
2. Sulfadimethoxine 3. Sulfamerazine 4. Sulfamethazine 5. Sulfanilamide 6. Sulfaquinoxaline 7. Sulfathiazole |
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Drug type: Enrofloxacin
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Fluoroquinolone
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Drug type: Lincomycin
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Lincosamide
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Drug type: Clarithromycin
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Macrolide
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Drug type: Chloramphenicol
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Phenicol
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Drug type: Azithromycin
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Macrolide
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Drug type:Trimethoprim
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Diaminopyrimidine
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Drug type:Sulfamerazine
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Sulfonamide
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Drug type: Tylosin
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Macrolide
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Drug Type: Cephalothin
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1st Generation (Parenteral)Cephalosporin
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Drug Type: Ceftriaxone
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3rd Generation (Parenteral)Cephalosporin
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Drug Type: Florfenicol
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Phenicol
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Drug Type: Danofloxacin
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Fluoroquinolone
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Drug Type: Clarithromycin
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Macrolide
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Drug type: Cefazolin
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1st Generation (Parenteral)Cephalosporin
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Drug type: Cefadroxil
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1st Generation (Oral)Cephalosporin
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Drug type: Cefotetan
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2nd Generation Cephalosporin
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Drug type: Ceftizoxime
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3rd Generation (Parenteral)Cephalosporin
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Drug type: Ceftriaxone
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3rd Generation (Parenteral)Cephalosporin
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Drug type: Cefepime
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4th Generation Cephalosporin
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Drug type: Cefquinome
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4th Generation Cephalosporin
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Drug type: Ceftazidime
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3rd Generation (Parenteral)Cephalosporin
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Drug type:Cephapirin
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1st Generation (Parenteral)Cephalosporin
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Drug type: Cephalexin
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1st Generation (oral)Cephalosporin
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Drug type: Cefadroxil
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1st Generation (oral)Cephalosporin
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Drug type:Cefpodoxime
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3rd Generation (oral)Cephalosporin
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Drug type:Cefixime
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3rd Generation (oral)Cephalosporin
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Drug type: Cefovecin
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3rd Generation (Parenteral)Cephalosporin
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Drug type: Cefuroxime
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2nd Generation Cephalosporin
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Drug type: Amoxicillin
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Beta-lactam-Penicillin- Aminopenicillin
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Drug type: Oxacillin
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Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin |
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Drug type: Carbenicillin
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Beta-lactam-Penicillin-
Antipseudomonal Penicillin |
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Drug type: Temocillin
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Beta-lactam-Penicillin-
Beta-Lactamase Resistant Penicillin |
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Drug type: Piperacillin
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Beta-lactam-Penicillin-
Antipseudomonal Penicillin |
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Drug type: Methicillin
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Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin |
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Drug type: Ampicillin
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Beta-lactam-Penicillin-
Aminopenicillin |
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Drug type: Hetacillin
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Beta-lactam-Penicillin-
Aminopenicillin |
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Drug type: Cloxacillin
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Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin |
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Drug type: Ticarcillin
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Beta-lactam-Penicillin-
Antipseudomonal Penicillin |
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Drug type: Dicloxacillin
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Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin |
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Drug type: Nafcillin
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Beta-lactam-Penicillin-
Penicillinase-Resistant Penicillin |
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6 Potentiated Sulfonamides
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1. Ormetoprim and Sulfadimethoxine
2. Pyrimethamine and Sulfadiazine 3. Pyrimethamine and Sulfaquinoxaline 4. Sulfadiazine and Trimethoprim 5. Sulfadoxine and Trimethoprim 6. Sulfamethoxazole and Trimethoprim |
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4 Tetracyclines
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1. Chlortetracycline
2. Doxycycline 3. Oxytetracycline 4. Tetracycline |
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3 Miscillaneous Antibiotics
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1. Metronidazole
2. Rifampin 3. Spectinomycin |
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Drug type: Spectinomycin
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Miscillaneous Antibiotic
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Drug type: Vancomycin
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Glycopeptide
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Drug type: Oxytetracycline
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Tetracycline
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Drug type: Sulfamethoxazole and Trimethoprim
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Potentiated Sulfonamide
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Drug type: Sulfathiazole
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Sulfonamide
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Drug type: Tulathromycin
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Macrolide
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Drug type: Rifampin
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Miscillaneous Antibiotic
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Drug type: Metronidazole
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Miscillaneous Antibiotic
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Drug type: Doxycycline
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Tetracycline
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Drug type: Chlortetracycline
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Tetracycline
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