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4 Cards in this Set
- Front
- Back
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(P) HALOPERIDOL
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TYPICAL ANTI-PSYCHOTIC
4: Schizophrenia other psychotic illnesses MECH: blocks DOP (D2), Alpha, serotonin, & histamine receptors - minimal cholinergic blocking CONTRAS: Parkinson's ADVERSES: EPS- (extrapyramidal symptoms ) b/c lack of Dop stimulation NEUROLEPTIC MALIGNANT SYNDROME **Asians = lower dose ** **Young Black Males more @ risk for dystonias** **Older women more @ risk for dyskinesia** *use low dose & DON'T GO ON AND OFF DRUG = more EPS** |
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(P) OLANZAPINE
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ATYPICAL ANTI-PSYCHOTIC
4: Schizophrenia bipolar mania MECH: blocks serotonin, Dop, muscarinic, Histamine (H1) & a1 receptors ADVERSES: sedation / drowsiness hyperglycemia TARTIVE DYSKINESIA (rare) NEUROLEPTIC MALIGNANT SYNDROME (rare) **elderlies more @risk for adverses** **monitor glucose levels** **give at BEDTIME** **NO RISK 4 AGRANULOCYTOSIS!** |
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(P) RIVASTIGMINE
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ALZHEIMER-TYPE DEMENTIA
4: Mild - moderate dementia MECH: inhibits AchE = more ACh in synapses carbamate derivates enhance cholinergic function ADVERSES: GI upset BRADYCARDIA **use small frequent meals** **Rxs with neuromuscular blocks since act at same synapses (succinylchloride)** |
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Atypical anti-psychotics differ from typicals b/c....?
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they only target SPECIFIC dopamine receptors
FEWER adverse effects |
